Identification of Circulating lncRNAs Associated with Gallbladder Cancer Risk by Tissue-Based Preselection, Cis-eQTL Validation, and Analysis of Association with Genotype-Based Expression.

Autor: Blandino A; Statistical Genetics Research Group, Institute of Medical Biometry, Heidelberg University, 69120 Heidelberg, Germany., Scherer D; Statistical Genetics Research Group, Institute of Medical Biometry, Heidelberg University, 69120 Heidelberg, Germany., Rounge TB; Department of Research, Cancer Registry of Norway, 0379 Oslo, Norway.; Department of Informatics, University of Oslo, 0304 Oslo, Norway., Umu SU; Department of Research, Cancer Registry of Norway, 0379 Oslo, Norway., Boekstegers F; Statistical Genetics Research Group, Institute of Medical Biometry, Heidelberg University, 69120 Heidelberg, Germany., Barahona Ponce C; Statistical Genetics Research Group, Institute of Medical Biometry, Heidelberg University, 69120 Heidelberg, Germany., Marcelain K; Department of Basic and Clinical Oncology, Medical Faculty, University of Chile, Santiago 8380000, Chile., Gárate-Calderón V; Statistical Genetics Research Group, Institute of Medical Biometry, Heidelberg University, 69120 Heidelberg, Germany.; Department of Basic and Clinical Oncology, Medical Faculty, University of Chile, Santiago 8380000, Chile., Waldenberger M; Research Unit Molecular Epidemiology and Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany., Morales E; Hospital Regional de Talca, Talca 3460000, Chile.; Facultad de Medicina, Universidad Católica del Maule, Talca 3460000, Chile., Rojas A; Facultad de Medicina, Universidad Católica del Maule, Talca 3460000, Chile., Munoz C; Hospital Regional de Talca, Talca 3460000, Chile.; Facultad de Medicina, Universidad Católica del Maule, Talca 3460000, Chile., Retamales J; Instituto Nacional del Cáncer, Santiago 7500650, Chile., de Toro G; Hospital de Puerto Montt, Puerto Montt 5480000, Chile.; Escuela de Tecnología Médica, Universidad Austral de Chile sede Puerto Montt, Puerto Montt 5480000, Chile., Barajas O; Department of Basic and Clinical Oncology, Medical Faculty, University of Chile, Santiago 8380000, Chile.; Hospital Clínico Universidad de Chile, Santiago 8380456, Chile., Rivera MT; Hospital del Salvador, Santiago 7500922, Chile., Cortés A; Hospital del Salvador, Santiago 7500922, Chile., Loader D; Hospital Padre Hurtado, Santiago 8880456, Chile., Saavedra J; Hospital Padre Hurtado, Santiago 8880456, Chile., Gutiérrez L; Hospital San Juan de Dios, Santiago, 8320000, Chile., Ortega A; Hospital Regional, Arica 1000000, Chile., Bertrán ME; Unidad Registro hospitalario de Cáncer, Hospital Base Valdivia, Valdivia 5090146, Chile., Gabler F; Hospital San Borja Arriarán, Santiago 8320000, Chile., Campos M; Hospital San Borja Arriarán, Santiago 8320000, Chile., Alvarado J; Hospital Regional Guillermo Grant Benavente, Concepcion 4070386, Chile., Moisán F; Hospital Regional Guillermo Grant Benavente, Concepcion 4070386, Chile., Spencer L; Hospital Regional Guillermo Grant Benavente, Concepcion 4070386, Chile., Nervi B; Departamento de Hematología y Oncología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago 8330077, Chile., Carvajal-Hausdorf DE; Facultad de Medicina, Clínica Alemana Universidad del Desarrollo, Santiago 7650568, Chile., Losada H; Hospital de Temuco, Temuco 4780000, Chile., Almau M; Hospital de Rancagua, Rancagua 2820000, Chile., Fernández P; Hospital de Rancagua, Rancagua 2820000, Chile., Gallegos I; Department of Basic and Clinical Oncology, Medical Faculty, University of Chile, Santiago 8380000, Chile.; Hospital Clínico Universidad de Chile, Santiago 8380456, Chile., Olloquequi J; Department of Biochemistry and Physiology, Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.; Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Talca 3460000, Chile., Fuentes-Guajardo M; Departamento de Tecnología Médica, Facultad de Ciencias de la Salud, Tarapacá University, Arica 1000815, Chile., Gonzalez-Jose R; Instituto Patagónico de Ciencias Sociales y Humanas, Centro Nacional Patagónico, CONICET, Puerto Madryn U9120ACD, Argentina., Bortolini MC; Instituto de Biociências, Universidad Federal do Rio Grande do Sul, Puerto Alegre 15053, Brazil., Gallo C; Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima 15102, Peru., Linares AR; Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center of Genetics and Development, School of Life Sciences and Human Phenome Institute, Fudan University, Shanghai 200434, China.; ADES (Anthropologie Bio-Culturelle, Droit, Éthique et Santé), UFR de Médecine, Aix-Marseille University, 13007 Marseille, France.; Department of Genetics, Evolution and Environment, UCL Genetics Institute, University College London, London WC1E 6BT, UK., Rothhammer F; Instituto de Alta Investigación, Tarapacá University, Arica 1000000, Chile., Lorenzo Bermejo J; Statistical Genetics Research Group, Institute of Medical Biometry, Heidelberg University, 69120 Heidelberg, Germany.

Publikováno v: Cancers [Cancers (Basel)] 2022 Jan 27; Vol. 14 (3). Date of Electronic Publication: 2022 Jan 27.

Multiplexed (18-Plex) Measurement of Signaling Targets and Cytotoxic T Cells in Trastuzumab-Treated Patients using Imaging Mass Cytometry.

Autor: Carvajal-Hausdorf DE; Yale School of Medicine, New Haven, Connecticut.; Clínica Alemana-Facultad de Medicina U. del Desarrollo, Santiago, Chile., Patsenker J; Yale School of Medicine, New Haven, Connecticut.; Rensselaer Polytechnic Institute, Troy, New York., Stanton KP; Yale School of Medicine, New Haven, Connecticut., Villarroel-Espindola F; Yale School of Medicine, New Haven, Connecticut., Esch A; Fluidigm Corporation, Markham, Ontario, Canada., Montgomery RR; Yale School of Medicine, New Haven, Connecticut., Psyrri A; Attikon University Hospital, Athens, Greece., Kalogeras KT; Translational Research Section, Hellenic Cooperative Oncology Group, Athens, Greece., Kotoula V; Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece., Foutzilas G; Department of Medical Oncology, 'Papageorgiou' Hospital, Athens, Greece., Schalper KA; Yale School of Medicine, New Haven, Connecticut., Kluger Y; Yale School of Medicine, New Haven, Connecticut., Rimm DL; Yale School of Medicine, New Haven, Connecticut. david.rimm@yale.edu.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2019 May 15; Vol. 25 (10), pp. 3054-3062. Date of Electronic Publication: 2019 Feb 22.

Macrodissection prior to closed system RT-qPCR is not necessary for estrogen receptor and HER2 concordance with IHC/FISH in breast cancer.

Autor: Gupta S; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA., Mani NR; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA., Carvajal-Hausdorf DE; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.; Anatomía Patológica, Clínica Alemana-Facultad de Medicina Universidad del Desarrollo, Santiago, Chile., Bossuyt V; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA., Ho K; Division of Oncology Research and Development, Oncology, Cepheid, Sunnyvale, CA, USA., Weidler J; Medical and Scientific Affairs and Strategy, Oncology, Cepheid, Sunnyvale, CA, USA., Wong W; Division of Oncology Research and Development, Oncology, Cepheid, Sunnyvale, CA, USA., Rhees B; Division of Oncology Research and Development, Oncology, Cepheid, Sunnyvale, CA, USA., Bates M; Medical and Scientific Affairs and Strategy, Oncology, Cepheid, Sunnyvale, CA, USA., Rimm DL; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA. david.rimm@yale.edu.

Publikováno v: Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2018 Aug; Vol. 98 (8), pp. 1076-1083. Date of Electronic Publication: 2018 Jun 01.

High concordance of a closed-system, RT-qPCR breast cancer assay for HER2 mRNA, compared to clinically determined immunohistochemistry, fluorescence in situ hybridization, and quantitative immunofluorescence.

Autor: Wasserman BE; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA., Carvajal-Hausdorf DE; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA., Ho K; Division of Oncology Research and Development, Cepheid, Sunnyvale, CA, USA., Wong W; Division of Oncology Research and Development, Cepheid, Sunnyvale, CA, USA., Wu N; Division of Oncology Research and Development, Cepheid, Sunnyvale, CA, USA., Chu VC; Division of Oncology Research and Development, Cepheid, Sunnyvale, CA, USA., Lai EW; Division of Oncology Research and Development, Cepheid, Sunnyvale, CA, USA., Weidler JM; Division of Oncology Research and Development, Cepheid, Sunnyvale, CA, USA., Bates M; Division of Oncology Research and Development, Cepheid, Sunnyvale, CA, USA., Neumeister V; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA., Rimm DL; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.

Publikováno v: Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2017 Dec; Vol. 97 (12), pp. 1521-1526. Date of Electronic Publication: 2017 Sep 11.

Erratum to: Effect of neoadjuvant chemotherapy on tumor-infiltrating lymphocytes and PD-L1 expression in breast cancer and its clinical significance.

Autor: Pelekanou V; Department of Pathology, Yale University School of Medicine, 310 Cedar St, PO Box 208023, New Haven, CT, 06520-8023, USA. vasiliki.pelekanou@yale.edu., Carvajal-Hausdorf DE; Department of Pathology, Yale University School of Medicine, 310 Cedar St, PO Box 208023, New Haven, CT, 06520-8023, USA., Altan M; Department of Medical Oncology, Yale University School of Medicine, New Haven, CT, USA., Wasserman B; Department of Pathology, Yale University School of Medicine, 310 Cedar St, PO Box 208023, New Haven, CT, 06520-8023, USA., Carvajal-Hausdorf C; Department of Medical Oncology, Yale University School of Medicine, New Haven, CT, USA., Wimberly H; Department of Pathology, Yale University School of Medicine, 310 Cedar St, PO Box 208023, New Haven, CT, 06520-8023, USA., Brown J; Department of Pathology, Yale University School of Medicine, 310 Cedar St, PO Box 208023, New Haven, CT, 06520-8023, USA., Lannin D; Department of Surgery, Yale University School of Medicine, New Haven, CT, USA., Pusztai L; Department of Medical Oncology, Yale University School of Medicine, New Haven, CT, USA., Rimm DL; Department of Pathology, Yale University School of Medicine, 310 Cedar St, PO Box 208023, New Haven, CT, 06520-8023, USA.; Department of Medical Oncology, Yale University School of Medicine, New Haven, CT, USA.

Publikováno v: Breast cancer research : BCR [Breast Cancer Res] 2017 Sep 25; Vol. 19 (1), pp. 109. Date of Electronic Publication: 2017 Sep 25.