Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Carter Barger"'
Autor:
Pavithra Viswanath, Joseph F. Costello, Sabrina M. Ronen, Anne Marie Gillespie, Carter Barger, Nicholas Stevers, Meryssa Tran, Céline Taglang, Georgios Batsios
Supplementary Data from Deuterium Metabolic Imaging Reports on TERT Expression and Early Response to Therapy in Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05496e235a0a55114e1a38818f5b8d89
https://doi.org/10.1158/1078-0432.22486155.v1
https://doi.org/10.1158/1078-0432.22486155.v1
Autor:
Pavithra Viswanath, Joseph F. Costello, Sabrina M. Ronen, Anne Marie Gillespie, Carter Barger, Nicholas Stevers, Meryssa Tran, Céline Taglang, Georgios Batsios
Purpose:Telomere maintenance is a hallmark of cancer. Most tumors maintain telomere length via reactivation of telomerase reverse transcriptase (TERT) expression. Identifying clinically translatable imaging biomarkers of TERT can enable noninvasive a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17635d9cf73cd690ff31f23d406a6c25
https://doi.org/10.1158/1078-0432.c.6532263
https://doi.org/10.1158/1078-0432.c.6532263
Autor:
Abigail Suwala, Carter Barger, Katarzyna M Soczek, Albert S Wang, Min Y Kim, Chibo Hong, Jennifer A Doudna, Susan M Chang, Joanna J Phillips, David A Solomon, Joseph F Costello
Publikováno v:
Neuro-Oncology. 24:vii117-vii117
Mutations in the TERT promoter are the single most common non-coding mutation in cancer and represent the genetic underpinnings of tumor cell immortality. Beyond the two most common point mutations, G228A and G250A, which selectively recruit the ETS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29d511d766d5e87d32b5f130f14378df
https://doi.org/10.1093/neuonc/noac209.443
https://doi.org/10.1093/neuonc/noac209.443
Autor:
Nicholas O. Stevers, Carter Barger, Olivia Lenzo, Chibo Hong, Katarzyna Soczek, Samuel H. Wu, Andrew M. McKinney, Abigail Suwala, Jennifer A. Doudna, Joseph F. Costello
Publikováno v:
Cancer Research. 82:2302-2302
Ninety percent of human tumors reactivate telomerase reverse transcriptase (TERT) to achieve cellular immortality. The route to immortality found in over 50 cancer types is mutation of the TERT promoter (TERTp) mutations. Studies in glioblastoma have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::847a8162b5d27efd587e841f72afe947
https://doi.org/10.1158/1538-7445.am2022-2302
https://doi.org/10.1158/1538-7445.am2022-2302