The Janus Role of Adhesion in Chondrogenesis

Autor: Ezequiel Perez-Inestrosa, Ignasi Casanellas, Anna Lagunas, Josep Samitier, Yolanda Vida, José A. Andrades, José Becerra

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
International Journal of Molecular Sciences
Volume 21
Issue 15
International Journal of Molecular Sciences, Vol 21, Iss 5269, p 5269 (2020)

Tackling the first stages of the chondrogenic commitment is essential to drive chondrogenic differentiation to healthy hyaline cartilage and minimize hypertrophy. During chondrogenesis, the extracellular matrix continuously evolves, adapting to the t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a7cac3b461ce6a76b5cbf7dff24ad2
https://hdl.handle.net/10668/16013

Development of a Three-Dimensional Bioengineered Platform for Articular Cartilage Regeneration

Autor: Lourdes Recha-Sancho, Soledad Pérez-Amodio, Miguel A. Mateos-Timoneda, Gerard Rubí-Sans, Carlos E. Semino, Elisabeth Engel

Publikováno v: Biomolecules, Vol 10, Iss 1, p 52 (2019)
Biomolecules
Volume 10
Issue 1
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)

Degenerative cartilage pathologies are nowadays a major problem for the world population. Factors such as age, genetics or obesity can predispose people to suffer from articular cartilage degeneration, which involves severe pain, loss of mobility and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813275ade99b599080f9a35d124d7639
https://www.mdpi.com/2218-273X/10/1/52

In vivo effect of opticin deficiency in cartilage in a surgically induced mouse model of osteoarthritis

Autor: Johanne Martel-Pelletier, Jordi Monfort, Gladys Valverde-Franco, Laura Tío, Bertrand Lussier, Aina Farran, Hassan Fahmi, Jean-Pierre Pelletier, Paul N. Bishop

Publikováno v: Farrán, A, Valverde-Franco, G, Tío, L, Lussier, B, Fahmi, H, Pelletier, J-P, Bishop, P N, Monfort, J & Martel-Pelletier, J 2018, ' In vivo effect of opticin deficiency in cartilage in a surgically induced mouse model of osteoarthritis ', Scientific Reports, vol. 8, no. 1, pp. 457 . https://doi.org/10.1038/s41598-017-18047-w
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports

The SLRP opticin (OPTC) has been demonstrated to be produced and degraded in osteoarthritic (OA) human cartilage. Here, we investigated the in vivo effect of OPTC deficiency in OA cartilage. OA was induced in 10-week-old Optc−/− and Optc+/+ mice.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac41d39af6c5a9d598a98114a38eb5ab
https://doi.org/10.1038/s41598-017-18047-w

Dedifferentiated Human Articular Chondrocytes Redifferentiate to a Cartilage-Like Tissue Phenotype in a Poly(ε-Caprolactone)/Self-Assembling Peptide Composite Scaffold

Autor: Farshid Guilak, Jordi Abella, Lourdes Recha-Sancho, Franklin T. Moutos, Carlos E. Semino

Publikováno v: Materials
RECERCAT (Dipòsit de la Recerca de Catalunya)
Recercat. Dipósit de la Recerca de Catalunya
instname
Materials, Vol 9, Iss 6, p 472 (2016)
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Materials; Volume 9; Issue 6; Pages: 472

Adult articular cartilage has a limited capacity for growth and regeneration and, with injury, new cellular or biomaterial-based therapeutic platforms are required to promote repair. Tissue engineering aims to produce cartilage-like tissues that recr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218d117898eca157d6645b55096eb205
https://pubmed.ncbi.nlm.nih.gov/28773609

Implantation of a polycaprolactone scaffold with subchondral bone anchoring ameliorates nodules formation and other tissue alterations

Autor: José Luis Gómez Ribelles, José A. Gómez-Tejedor, L. Vikingsson, Santos Martínez Díaz, María Sancho-Tello, Joan Carles Monllau, Amparo Ruiz-Sauri, Gloria Gallego Ferrer, Carmen Carda

Publikováno v: RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname

Purpose: Articular cartilage has limited repair capacity. Two different implant devices for articular cartilage regeneration were tested in vivo in a sheep model to evaluate the effect of subchondral bone anchoring for tissue repair. Methods: The imp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e7cfacf23f8665440d38d49f40c09d
https://hdl.handle.net/10251/74862