Optimized ACE2 decoys neutralize antibody-resistant SARS-CoV-2 variants through functional receptor mimicry and treat infection in vivo.

Autor: Torchia JA; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA., Tavares AH; National Emerging Infectious Diseases Laboratories (NEIDL), Boston University, Boston, MA 02118, USA.; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA., Carstensen LS; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA., Chen DY; National Emerging Infectious Diseases Laboratories (NEIDL), Boston University, Boston, MA 02118, USA.; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA., Huang J; Center for Regenerative Medicine of Boston University, Boston Medical Center, and The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA., Xiao T; Division of Pediatrics, Harvard Medical School, Boston, MA 02115, USA., Mukherjee S; Vaccine and Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA., Reeves PM; Vaccine and Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA., Tu H; LakePharma Inc., San Carlos, CA 94070, USA., Sluder AE; Vaccine and Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA., Chen B; Division of Pediatrics, Harvard Medical School, Boston, MA 02115, USA., Kotton DN; Center for Regenerative Medicine of Boston University, Boston Medical Center, and The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA., Bowen RA; Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA., Saeed M; National Emerging Infectious Diseases Laboratories (NEIDL), Boston University, Boston, MA 02118, USA.; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA., Poznansky MC; Vaccine and Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA., Freeman GJ; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA.

Publikováno v: Science advances [Sci Adv] 2022 Dec 09; Vol. 8 (49), pp. eabq6527. Date of Electronic Publication: 2022 Dec 07.

Water usage, hygiene and diarrhea in low-income urban communities-A mixed method prospective longitudinal study.

Autor: Sultana R; Copenhagen Center for Disaster Research, Section for Global Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.; Institute of Health Economics, University of Dhaka, Dhaka, Bangladesh.; icddr,b, Dhaka, Bangladesh., Tamason CC; Copenhagen Center for Disaster Research, Section for Global Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Carstensen LS; Copenhagen Center for Disaster Research, Section for Global Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Ferdous J; Copenhagen Center for Disaster Research, Section for Global Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.; Department of Microbiology, University of Dhaka, Dhaka, Bangladesh., Hossain ZZ; Copenhagen Center for Disaster Research, Section for Global Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.; Department of Microbiology, University of Dhaka, Dhaka, Bangladesh., Begum A; Department of Microbiology, University of Dhaka, Dhaka, Bangladesh., Jensen PKM; Copenhagen Center for Disaster Research, Section for Global Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

Publikováno v: MethodsX [MethodsX] 2019 Nov 19; Vol. 6, pp. 2822-2837. Date of Electronic Publication: 2019 Nov 19 (Print Publication: 2019).