Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Carsten Voss"'
Publikováno v:
Current Protein & Peptide Science. 20:65-74
Background:Mixed-mode chromatography is becoming an important tool for downstream process purification, as it provides the selectivity and robustness unmatched by conventional singlemode chromatographic methods. The joint action of multiple functiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e5968c7f827361f137b933fba5275d
https://doi.org/10.2174/1389203718666171017130506
https://doi.org/10.2174/1389203718666171017130506
Publikováno v:
Chemie Ingenieur Technik. 80:831-837
Die Verteilung von RNA und Plasmid-DNA wurde in einem inversmizellaren Zweiphasensystem bestehend aus Trioctylmethylammoniumchlorid (TOMAC) und Isooctan untersucht. Die Auswirkung verschiedener Salze und Alkohole auf den Transfer der Nukleinsauren wu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b766ec53a734aaf654a3ac64c58cef6b
https://doi.org/10.1002/cite.200800037
https://doi.org/10.1002/cite.200800037
Autor:
Carsten Voß
Publikováno v:
Chemie Ingenieur Technik. 80:795-802
Plasmid-DNA wird als Klonierungsvektor zum Einbringen rekombinanter Gene in Mikroorganismen genutzt. Seit den 1990er Jahren wird dieses Prinzip auch zur Ubertragung therapeutischer Gene in der Gentherapie und der genetischen Impfung verwendet. Diese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d418a478c82e96470e28b1656dd0cf8e
https://doi.org/10.1002/cite.200800032
https://doi.org/10.1002/cite.200800032
Publikováno v:
CHEMKON. 15:19-24
Der Begriff „Thermochromie”T leitet sich aus den griechischen Bezeichnungen fur Warme („thermos”) und Farbe („chroma”) ab. Bezeichnet wird damit das Auftreten reversibler Farbanderungen von Stoffen in Abhangigkeit von der Temperatur. Ents
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https://explore.openaire.eu/search/publication?articleId=doi_________::4b923c10519ff4d1b8cbc117065dd1b0
https://doi.org/10.1002/ckon.200810068
https://doi.org/10.1002/ckon.200810068
Publikováno v:
Journal of Biotechnology. 131:188-196
Plasmid DNA as an active pharmaceutical ingredient (API) is gaining more and more importance. For the production of multigram quantities of this substance robust and scalable processes comprising several purification steps have to be designed. One ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dab594d6784149bb87700f65bf42d62
https://doi.org/10.1016/j.jbiotec.2007.06.011
https://doi.org/10.1016/j.jbiotec.2007.06.011
Publikováno v:
Journal of Chemical Technology & Biotechnology. 79:57-62
In this paper the influence of ammonium salt concentration on the production of pharmaceutical grade plasmid DNA from unfed high cell density batch culture on synthetic glycerol media is presented. Ammonium chloride in different concentrations (0 mmo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5eaba6bbce2e57ccbeb7d61ad9513ee
https://doi.org/10.1002/jctb.941
https://doi.org/10.1002/jctb.941
Publikováno v:
Journal of Biotechnology. 105:205-213
Production of nucleic acids as an active pharmaceutical ingredient (API) in gene therapy and genetic vaccination is gaining more and more importance. Non-viral vectors like plasmid DNA are currently investigated in various clinical trials. Supercoile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce024826d2d1692d6d3790667244b25d
https://doi.org/10.1016/j.jbiotec.2003.07.004
https://doi.org/10.1016/j.jbiotec.2003.07.004
Autor:
Thomas Nellessen, Iduna Fichtner, Carsten Voss, Peter M. Schlag, Wolfgang Walther, Ulrike Stein, Martin Schleef, Torsten Schmidt
Publikováno v:
Molecular Biotechnology. 21:105-116
Jet-injection has become an applicable technology among other established nonviral delivery systems, such as particle bombardment or in vivo electroporation. The low-volume jet injector employed in this study uses compressed air to inject solutions o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f9a88c770096932510cd7bef26d581
https://doi.org/10.1385/mb:21:2:105
https://doi.org/10.1385/mb:21:2:105
The separation of structurally related impurities from pharmaceutical plasmid DNA by highly scalable purification techniques is a challenge for biochemical engineering. Next to RNA, proteins, and lipopolysaccharides, the chromosomal DNA of the plasmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496ff0b1ab0595567d60e9d9bd4b36e1
https://doi.org/10.1007/s00253-009-2088-3
https://doi.org/10.1007/s00253-009-2088-3
Autor:
Carsten, Voss
Publikováno v:
Biotechnology annual review. 13
The concept of curing diseases at the genetic level was already introduced in the 1970s, but only the evolution of molecular biology and tools for genetic manipulation brought the idea into labs and clinics during the last 16 years. Viral and non-vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::813a82de07b521511f4f9d0a48cf0525
https://pubmed.ncbi.nlm.nih.gov/17875478
https://pubmed.ncbi.nlm.nih.gov/17875478