Zobrazeno 1 - 10
of 298
pro vyhledávání: '"Carsten Sticht"'
Autor:
Raisatun Nisa Sugiyanto, Carmen Metzger, Aslihan Inal, Felicia Truckenmueller, Kira Gür, Eva Eiteneuer, Thorben Huth, Angelika Fraas, Ivonne Heinze, Joanna Kirkpatrick, Carsten Sticht, Thomas Albrecht, Benjamin Goeppert, Tanja Poth, Stefan Pusch, Arianeb Mehrabi, Peter Schirmacher, Junfang Ji, Alessandro Ori, Stephanie Roessler
Publikováno v:
Cell Death and Disease, Vol 15, Iss 10, Pp 1-15 (2024)
Abstract Gallbladder cancer (GBC) presents as an aggressive malignancy with poor patient outcome. Like other epithelial cancers, the mechanisms of GBC cancer progression remain vague and efforts in finding targeted therapies fall below expectations.
Externí odkaz:
https://doaj.org/article/df85100152ce447f8f594f4c06a2e153
Autor:
Michael Albrecht, Carsten Sticht, Tabea Wagner, Steffen A. Hettler, Carolina De La Torre, Jiedong Qiu, Norbert Gretz, Thomas Albrecht, Benito Yard, Jonathan P. Sleeman, Boyan K. Garvalov
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract In diabetic nephropathy (DN), glomerular endothelial cells (GECs) and podocytes undergo pathological alterations, which are influenced by metabolic changes characteristic of diabetes, including hyperglycaemia (HG) and elevated methylglyoxal
Externí odkaz:
https://doaj.org/article/5f11865b1b404ee3a36eeb1be0df89ad
Autor:
Seddik Hammad, Christoph Ogris, Amnah Othman, Pia Erdoesi, Wolfgang Schmidt-Heck, Ina Biermayer, Barbara Helm, Yan Gao, Weronika Piorońska, Christian H. Holland, Lorenza A. D’Alessandro, Carolina de la Torre, Carsten Sticht, Sherin Al Aoua, Fabian J. Theis, Heike Bantel, Matthias P. Ebert, Ursula Klingmüller, Jan G. Hengstler, Steven Dooley, Nikola S. Mueller
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-13 (2023)
Abstract The human liver has a remarkable capacity to regenerate and thus compensate over decades for fibrosis caused by toxic chemicals, drugs, alcohol, or malnutrition. To date, no protective mechanisms have been identified that help the liver tole
Externí odkaz:
https://doaj.org/article/51b08471f4314fc5a23b5a9f8fd9aea5
Autor:
Erika Rendra, Adriana Torres Crigna, Cristina Daniele, Carsten Sticht, Maike Cueppers, Mark Andreas Kluth, Christoph Ganss, Markus H. Frank, Norbert Gretz, Karen Bieback
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Acute kidney injury (AKI) is characterized by a rapid reduction in renal function and glomerular filtration rate (GFR). The broadly used anti-cancer chemotherapeutic agent cisplatin often induces AKI as an adverse drug side effect. Therapies targeted
Externí odkaz:
https://doaj.org/article/eda2ae136f194118a0671792b264cd29
Autor:
Xin Qian, Stephan Klatt, Katrin Bennewitz, David Philipp Wohlfart, Bowen Lou, Ye Meng, Michael Buettner, Gernot Poschet, Jakob Morgenstern, Thomas Fleming, Carsten Sticht, Ingrid Hausser, Ingrid Fleming, Julia Szendroedi, Peter Paul Nawroth, Jens Kroll
Publikováno v:
Advanced Science, Vol 11, Iss 4, Pp n/a-n/a (2024)
Abstract Omega‐6 fatty acids are the primary polyunsaturated fatty acids in most Western diets, while their role in diabetes remains controversial. Exposure of omega‐6 fatty acids to an oxidative environment results in the generation of a highly
Externí odkaz:
https://doaj.org/article/d3e9abcfffc843caa8b54bf9e9a82f24
Autor:
Christopher Groth, Jovana Maric, Irene Garcés Lázaro, Tomáš Hofman, Zhenfeng Zhang, Yi Ni, Franziska Keller, Isabelle Seufert, Maike Hofmann, Christoph Neumann-Haefelin, Carsten Sticht, Karsten Rippe, Stephan Urban, Adelheid Cerwenka
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Background and aimsThe co-infection of hepatitis B (HBV) patients with the hepatitis D virus (HDV) causes the most severe form of viral hepatitis and thus drastically worsens the course of the disease. Therapy options for HBV/HDV patients are still l
Externí odkaz:
https://doaj.org/article/69f06fc2d2344f00ab63a7b560570dad
Autor:
Bianca Dietsch, Céline Weller, Carsten Sticht, Carolina de la Torre, Martin Kramer, Sergij Goerdt, Cyrill Géraud, Sebastian A. Wohlfeil
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Background Liver metastasis is a poor prognostic factor for treatment of advanced cutaneous melanoma with either immunotherapy or targeted therapies. In this study we focused on NRAS mutated melanoma, a cohort with high unmet clinical need.
Externí odkaz:
https://doaj.org/article/ef731503ce0e4d28b81d40a5d89c4f70
Autor:
Anna Sophia Jauch, Sebastian A. Wohlfeil, Céline Weller, Bianca Dietsch, Verena Häfele, Ana Stojanovic, Maximilian Kittel, Hendrik Nolte, Adelheid Cerwenka, Michael Neumaier, Kai Schledzewski, Carsten Sticht, Philipp-Sebastian Reiners-Koch, Sergij Goerdt, Cyrill Géraud
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background Hyaluronan receptor LYVE-1 is expressed by liver sinusoidal endothelial cells (LSEC), lymphatic endothelial cells and specialized macrophages. Besides binding to hyaluronan, LYVE-1 can mediate adhesion of leukocytes and cancer cel
Externí odkaz:
https://doaj.org/article/7e8fd3d8dbfa4f958989dc52cbddebc7
Autor:
Sabine Heumüller-Klug, Kristina Maurer, María Á. Tapia-Laliena, Carsten Sticht, Anne Christmann, Handan Mörz, Rasul Khasanov, Elvira Wink, Steven Schulte, Wolfgang Greffrath, Rolf-Detlef Treede, Lucas M. Wessel, Karl-Herbert Schäfer
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Impairment of both the central and peripheral nervous system is a major cause of mortality and disability. It varies from an affection of the brain to various types of enteric dysganglionosis. Congenital enteric dysganglionosis is chara
Externí odkaz:
https://doaj.org/article/0f6353f60cbc4231843e2f54d8222b42
Autor:
Jian Zhang, Vytaute Starkuviene, Holger Erfle, Zhaohui Wang, Manuel Gunkel, Ziwei Zeng, Carsten Sticht, Kejia Kan, Nuh Rahbari, Michael Keese
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract In response to vascular injury vascular smooth muscle cells (VSMCs) alternate between a differentiated (contractile) and a dedifferentiated (synthetic) state or phenotype. Although parts of the signaling cascade regulating the phenotypic swi
Externí odkaz:
https://doaj.org/article/a7ab47dfccb9422cbc7f1f64a29359f7