Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Carsten Kirschning"'
Autor:
Maja Wyczanska, Jana Rohling, Ursula Keller, Marcus R. Benz, Carsten Kirschning, Bärbel Lange-Sperandio
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/a03ad202a5914eed97ffde1e153dc298
Autor:
Qian Li, Jun Wang, Heba Islam, Carsten Kirschning, Hongzhou Lu, Daniel Hoffmann, Ulf Dittmer, Mengji Lu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Host immune control plays a pivotal role in resolving primary hepatitis-B-virus (HBV) infections. The complex interaction between HBV and host immune cells, however, remains unclear. In this study, the transcriptional profiling of specimens
Externí odkaz:
https://doaj.org/article/e290f8c78e7344028250f567770e8611
Autor:
Xiaoli Yang, Shafaqat Ali, Manman Zhao, Lisa Richter, Vanessa Schäfer, Julian Schliehe-Diecks, Marian Frank, Jing Qi, Pia-Katharina Larsen, Jennifer Skerra, Heba Islam, Thorsten Wachtmeister, Christina Alter, Anfei Huang, Sanil Bhatia, Karl Köhrer, Carsten Kirschning, Heike Weighardt, Ulrich Kalinke, Rainer Kalscheuer, Markus Uhrberg, Stefanie Scheu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Beauvericin (BEA), a mycotoxin of the enniatin family produced by various toxigenic fungi, has been attributed multiple biological activities such as anti-cancer, anti-inflammatory, and anti-microbial functions. However, effects of BEA on dendritic c
Externí odkaz:
https://doaj.org/article/e7db736d19e84cc1b3620305b013c974
Autor:
Holger Kleinertz, Monika Hepner-Schefczyk, Sabrina Ehnert, Maren Claus, Rebecca Halbgebauer, Lea Boller, Markus Huber-Lang, Paolo Cinelli, Carsten Kirschning, Sascha Flohé, André Sander, Christian Waydhas, Sonja Vonderhagen, Marcus Jäger, Marcel Dudda, Carsten Watzl, Stefanie B. Flohé
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 380-391 (2019)
Background: Systemic inflammation induced by sterile or infectious insults is associated with an enhanced susceptibility to life-threatening opportunistic, mostly bacterial, infections due to unknown pathogenesis. Natural killer (NK) cells contribute
Externí odkaz:
https://doaj.org/article/4ca31e8a7d634af59a4318c77a8f7f16
Autor:
Qian Li, Yan Yan, Jia Liu, Xuan Huang, Xiaoyong Zhang, Carsten Kirschning, Haifeng C. Xu, Philipp A. Lang, Ulf Dittmer, Ejuan Zhang, Mengji Lu
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The activation of TLR7 signaling in T cells accelerates antigen-specific responses. Such responses play an essential role in eliminating viral infections and can be anti-tumorigenic. However, the underlying mechanisms of how TLR7 can promote the opti
Externí odkaz:
https://doaj.org/article/c0fd1dadd583432e942e6b3f03ce4c00
Autor:
Rebecca Heß, Michael Storcksdieck genannt Bonsmann, Dennis Lapuente, Andre Maaske, Carsten Kirschning, Jürgen Ruland, Bernd Lepenies, Drew Hannaman, Matthias Tenbusch, Klaus Überla
Publikováno v:
Viruses, Vol 11, Iss 2, p 153 (2019)
The envelope protein (Env) is the only surface protein of the human immunodeficiency virus (HIV) and as such the exclusive target for protective antibody responses. Experimental evidences from mouse models suggest a modulating property of Env to stee
Externí odkaz:
https://doaj.org/article/90e6b244a6a44491b6d80bc42f5bcd08
Autor:
Christiane Desel, Kerstin Werninghaus, Manuel Ritter, Katrin Jozefowski, Jens Wenzel, Norman Russkamp, Ulrike Schleicher, Dennis Christensen, Stefan Wirtz, Carsten Kirschning, Else Marie Agger, Clarissa Prazeres da Costa, Roland Lang
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53531 (2013)
Successful vaccination against intracellular pathogens requires the generation of cellular immune responses. Trehalose-6,6-dibehenate (TDB), the synthetic analog of the mycobacterial cord factor trehalose-6,6-dimycolate (TDM), is a potent adjuvant in
Externí odkaz:
https://doaj.org/article/07f3cc05683f4995b5ef612e67c6f3be
Autor:
Else Marie Agger, Ida Rosenkrands, Jon Hansen, Karima Brahimi, Brian S Vandahl, Claus Aagaard, Kerstin Werninghaus, Carsten Kirschning, Roland Lang, Dennis Christensen, Michael Theisen, Frank Follmann, Peter Andersen
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3116 (2008)
BACKGROUND: It is now emerging that for vaccines against a range of diseases including influenza, malaria and HIV, the induction of a humoral response is insufficient and a substantial complementary cell-mediated immune response is necessary for adeq
Externí odkaz:
https://doaj.org/article/f7a3d3c923cf4956b513c2cd03d643c7
Autor:
Viktor Umansky, Peter Altevogt, Jochen Utikal, Vincenzo Bronte, Carsten Kirschning, Vasyl Nagibin, Qian Sun, Laura Hüser, Zeno Riester, Christopher Groth, Rebekka Weber, Céline Weller, Xiaoying Hu, Viktor Fleming
Tumor cell–derived extracellular vesicles (EV) convert normal myeloid cells into myeloid-derived suppressor cells (MDSC), inhibiting antitumor immune responses. Here, we show that EV from Ret mouse melanoma cells upregulate the expression of progra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30134e5df523fa5d595f477cc6671751
https://doi.org/10.1158/0008-5472.c.6511317.v1
https://doi.org/10.1158/0008-5472.c.6511317.v1
Autor:
Viktor Umansky, Peter Altevogt, Jochen Utikal, Vincenzo Bronte, Carsten Kirschning, Vasyl Nagibin, Qian Sun, Laura Hüser, Zeno Riester, Christopher Groth, Rebekka Weber, Céline Weller, Xiaoying Hu, Viktor Fleming
Figure S1 shows PD-L1 upregulation induced by EV that is mediated by NF-kB activation; Figure S2 shows an induction of PD-L1 and immunosuppressive capacity of myeloid cells through TLR signaling; Figure S3 presents characterization of EV derived from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15cecab5e60228f0bc40f6e2d39a8b7d
https://doi.org/10.1158/0008-5472.22422705
https://doi.org/10.1158/0008-5472.22422705