Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Carsten Jörn Beese"'
Autor:
Aida Rodríguez López, Maria H. Jørgensen, Jesper F. Havelund, Frederic S. Arendrup, Srinivasa Prasad Kolapalli, Thorbjørn M. Nielsen, Eva Pais, Carsten Jörn Beese, Ahmad Abdul-Al, Anna Constance Vind, Jiri Bartek, Simon Bekker-Jensen, Marta Montes, Panagiotis Galanos, Nils Faergeman, Lotta Happonen, Lisa B. Frankel
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113381- (2023)
Summary: Oncogene-induced senescence (OIS) is a persistent anti-proliferative response that acts as a barrier against malignant transformation. During OIS, cells undergo dynamic remodeling, which involves alterations in protein and organelle homeosta
Externí odkaz:
https://doaj.org/article/194106ee156b484ca5a608d3be2c0d91
Autor:
Paula A. Marin Zapata, Oscar Méndez-Lucio, Tuan Le, Carsten Jörn Beese, Jörg Wichard, David Rouquié, Djork-Arné Clevert
Publikováno v:
Digital Discovery. 2:91-102
Cellular morphology can be used to guide the de novo design of small molecules inducing a desired phenotype.
Autor:
Anne Hamacher-Brady, Carsten Jörn Beese, Anja Jünger, Nathan R. Brady, Paula Andrea Marin Zapata, Giovanni Dalmasso
Publikováno v:
BMC Cancer
Background TFEB (transcription factor EB) regulates metabolic homeostasis through its activation of lysosomal biogenesis following its nuclear translocation. TFEB activity is inhibited by mTOR phosphorylation, which signals its cytoplasmic retention.