Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Carsten Gründker"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13705 (2023)
Whether G protein-coupled estrogen receptor 1 (GPER1) is tumor-promoting or tumor-suppressive depends in part on tumor entity. Little is known about the function of GPER1 in vulvar carcinoma. In this work, we aim to clarify what role GPER1 plays in v
Externí odkaz:
https://doaj.org/article/feeac7c9649e4972ab9e1b23ea3a9c76
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 5050 (2022)
Despite all precautionary actions and the possibility of using vaccinations to counteract infections caused by human papillomaviruses (HPVs), HPV-related cancers still account for approximately 5% of all carcinomas. Worldwide, many women are still ex
Externí odkaz:
https://doaj.org/article/5a2cc2b697424a29ac2a6789d9518adf
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Since the earliest findings of Otto Warburg, who discovered the first metabolic differences between lactate production of cancer cells and non-malignant tissues in the 1920s, much time has passed. He explained the increased lactate levels with dysfun
Externí odkaz:
https://doaj.org/article/3c9c524c2867430799d5cdeb8ecc43d6
Publikováno v:
Anticancer Research. 42:5187-5194
G protein-coupled estrogen receptor 1 (GPER1) is often over-expressed in triple negative breast cancer (TNBC). GPER1 is responsible for many of the non-genomic, membrane-initiated effects of estrogens. Therefore, we have analyzed the effects of GPER1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5129d9724f96effb777ddf929dac84c4
https://doi.org/10.21873/anticanres.16025
https://doi.org/10.21873/anticanres.16025
Publikováno v:
Cells, Vol 10, Iss 9, p 2398 (2021)
Cancer cells have an increased need for glucose and, despite aerobic conditions, obtain their energy through aerobic oxidation and lactate fermentation, instead of aerobic oxidation alone. Glutamine is an essential amino acid in the human body. Gluta
Externí odkaz:
https://doaj.org/article/8f2c8cbfc852411ba83a4221c20cd834
Autor:
Johanna W. Hellinger, Silke Hüchel, Lena Goetz, Gerd Bauerschmitz, Günter Emons, Carsten Gründker
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Background and Objective: Matricellular proteins modulate the micro environment of tumors and are recognized to contribute to tumor cell invasion and dissemination. The cysteine-rich angiogenic inducer 61 (CYR61) is upregulated in mesenchymal transfo
Externí odkaz:
https://doaj.org/article/027b2ed8a09a497286b894840efd14e2
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2019)
Estrogen receptors are important regulators of the growth of breast tumors. Three different receptors for estrogens have been identified in breast tumors, two nuclear receptors, ERα and ERβ, and a G-protein coupled estrogen receptor 1 (GPER) that i
Externí odkaz:
https://doaj.org/article/25ce9b08c9b1491fb7801611fcfff9e5
Publikováno v:
Cells, Vol 10, Iss 3, p 714 (2021)
Cervical cancer is responsible for around 5% of all human cancers worldwide. It develops almost exclusively from an unsolved, persistent infection of the squamocolumnar transformation zone between the endo- and ecto-cervix with various high-risk (HR)
Externí odkaz:
https://doaj.org/article/17d44c4447054a73a48e3901eadee178
Autor:
Günter Emons, Carsten Gründker
Publikováno v:
Cells, Vol 10, Iss 2, p 292 (2021)
Endometrial cancer (EC) is one of the most common gynecological malignancies. Gonadotropin releasing hormone (GnRH) is a decapeptide first described to be secreted by the hypothalamus to regulate pituitary gonadotropin secretion. In this systematic r
Externí odkaz:
https://doaj.org/article/e7e2766b22324ce0b97df9e11b319abc
Autor:
Carsten Gründker, Günter Emons
Publikováno v:
Cells, Vol 10, Iss 2, p 437 (2021)
The hypothalamus–pituitary–gonadal (HPG) axis is the endocrine regulation system that controls the woman’s cycle. The gonadotropin-releasing hormone (GnRH) plays the central role. In addition to the gonadotrophic cells of the pituitary, GnRH re
Externí odkaz:
https://doaj.org/article/a51a066e65a441dbb6ddf5ee32f36528