Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Carsten Gnewuch"'
Autor:
Thorsten Kaiser, Benedict Kinny-Köster, Carsten Gnewuch, Diana Karailieva, Michael Kiehntopf, Anja Kessler, Christina Ritter-Sket, Michael Schmidt, Korbinian Brand, Joachim Thiery, Ralf Lichtinghagen
Publikováno v:
Practical Laboratory Medicine, Vol 8, Iss , Pp 41-48 (2017)
Background & aim: Patients with end-stage liver disease require valid estimations of mortality for organ allocation and risk stratification. The model of end-stage liver disease (MELD) score is used for this purpose in most countries and incorporates
Externí odkaz:
https://doaj.org/article/e5fbb0d37c0245e58c650ac31c69132b
Autor:
Wilmar Igl, Afaf Kamal-Eldin, Åsa Johansson, Gerhard Liebisch, Carsten Gnewuch, Gerd Schmitz, Ulf Gyllensten
Publikováno v:
International Journal of Circumpolar Health, Vol 72, Iss 0, Pp 1-7 (2013)
Background . The high intake of game meat in populations with a subsistence-based diet may affect their blood lipids and health status. Objective . To examine the association between diet and circulating levels of blood lipid levels in a northern Swe
Externí odkaz:
https://doaj.org/article/82edff725b304dcdbd0e2cd35fa586fe
Autor:
Ayşe Demirkan, Cornelia M van Duijn, Peter Ugocsai, Aaron Isaacs, Peter P Pramstaller, Gerhard Liebisch, James F Wilson, Åsa Johansson, Igor Rudan, Yurii S Aulchenko, Anatoly V Kirichenko, A Cecile J W Janssens, Ritsert C Jansen, Carsten Gnewuch, Francisco S Domingues, Cristian Pattaro, Sarah H Wild, Inger Jonasson, Ozren Polasek, Irina V Zorkoltseva, Albert Hofman, Lennart C Karssen, Maksim Struchalin, James Floyd, Wilmar Igl, Zrinka Biloglav, Linda Broer, Arne Pfeufer, Irene Pichler, Susan Campbell, Ghazal Zaboli, Ivana Kolcic, Fernando Rivadeneira, Jennifer Huffman, Nicholas D Hastie, Andre Uitterlinden, Lude Franke, Christopher S Franklin, Veronique Vitart, DIAGRAM Consortium, Christopher P Nelson, Michael Preuss, CARDIoGRAM Consortium, Joshua C Bis, Christopher J O'Donnell, Nora Franceschini, CHARGE Consortium, Jacqueline C M Witteman, Tatiana Axenovich, Ben A Oostra, Thomas Meitinger, Andrew A Hicks, Caroline Hayward, Alan F Wright, Ulf Gyllensten, Harry Campbell, Gerd Schmitz, EUROSPAN consortium
Publikováno v:
PLoS Genetics, Vol 8, Iss 2, p e1002490 (2012)
Phospho- and sphingolipids are crucial cellular and intracellular compounds. These lipids are required for active transport, a number of enzymatic processes, membrane formation, and cell signalling. Disruption of their metabolism leads to several dis
Externí odkaz:
https://doaj.org/article/1056cf3c6b034729babb9ff6cf53a034
Autor:
Wilmar Igl, Asa Johansson, James F Wilson, Sarah H Wild, Ozren Polasek, Caroline Hayward, Veronique Vitart, Nicholas Hastie, Pavao Rudan, Carsten Gnewuch, Gerd Schmitz, Thomas Meitinger, Peter P Pramstaller, Andrew A Hicks, Ben A Oostra, Cornelia M van Duijn, Igor Rudan, Alan Wright, Harry Campbell, Ulf Gyllensten, EUROSPAN Consortium
Publikováno v:
PLoS Genetics, Vol 6, Iss 1, p e1000798 (2010)
Genome-wide association studies (GWAS) have identified 38 larger genetic regions affecting classical blood lipid levels without adjusting for important environmental influences. We modeled diet and physical activity in a GWAS in order to identify nov
Externí odkaz:
https://doaj.org/article/2c8e3e6d842c430892f9814d0afc6139
Autor:
Andrew A Hicks, Peter P Pramstaller, Asa Johansson, Veronique Vitart, Igor Rudan, Peter Ugocsai, Yurii Aulchenko, Christopher S Franklin, Gerhard Liebisch, Jeanette Erdmann, Inger Jonasson, Irina V Zorkoltseva, Cristian Pattaro, Caroline Hayward, Aaron Isaacs, Christian Hengstenberg, Susan Campbell, Carsten Gnewuch, A Cecilej W Janssens, Anatoly V Kirichenko, Inke R König, Fabio Marroni, Ozren Polasek, Ayse Demirkan, Ivana Kolcic, Christine Schwienbacher, Wilmar Igl, Zrinka Biloglav, Jacqueline C M Witteman, Irene Pichler, Ghazal Zaboli, Tatiana I Axenovich, Annette Peters, Stefan Schreiber, H-Erich Wichmann, Heribert Schunkert, Nick Hastie, Ben A Oostra, Sarah H Wild, Thomas Meitinger, Ulf Gyllensten, Cornelia M van Duijn, James F Wilson, Alan Wright, Gerd Schmitz, Harry Campbell
Publikováno v:
PLoS Genetics, Vol 5, Iss 10, p e1000672 (2009)
Sphingolipids have essential roles as structural components of cell membranes and in cell signalling, and disruption of their metabolism causes several diseases, with diverse neurological, psychiatric, and metabolic consequences. Increasingly, varian
Externí odkaz:
https://doaj.org/article/630ba93c59ca4f4f8f8c46c77baec03e
Autor:
Florian Zeman, Bernhard M. Graf, Joshua Riedel, Hans J. Schlitt, Tobias Bergler, Carsten Gnewuch, Birgit Tege, Laszlo Halmy, Volker Linder, Ivan Göcze
Publikováno v:
Journal of Clinical Medicine
Volume 10
Issue 21
Journal of Clinical Medicine, Vol 10, Iss 5122, p 5122 (2021)
Volume 10
Issue 21
Journal of Clinical Medicine, Vol 10, Iss 5122, p 5122 (2021)
Background: The facilitation of early recovery of acute kidney injury (AKI) is an important step to improve outcome, particularly because of the limited therapeutic interventions currently available for AKI. The combination of an electronic alert and
Autor:
Ivan Göcze, Florian Zeman, Bernhard Banas, Carsten Gnewuch, Dominik Jauch, Pascal Kennedy, Bernhard M. Graf, Hans J. Schlitt, Markus Götz, Thomas Bein, Wolfgang Gnann, Tobias Bergler, Bettina Jung
Publikováno v:
Annals of Surgery. 267:1013-1020
To determine the impact of renal biomarker-guided implementation of the Kidney Disease Improving Global Outcomes (KDIGO) care bundle on the incidence of acute kidney injury (AKI) after major noncardiac surgery in a single-center unblinded randomized
Autor:
Ralf Lichtinghagen, Thorsten Kaiser, Korbinian Brand, Michael Kiehntopf, Diana Karailieva, Christina Ritter-Sket, Anja Kessler, Carsten Gnewuch, Benedict Kinny-Köster, Michael Schmidt, Joachim Thiery
Publikováno v:
Practical Laboratory Medicine
Practical Laboratory Medicine, Vol 8, Iss, Pp 41-48 (2017)
Practical Laboratory Medicine, Vol 8, Iss, Pp 41-48 (2017)
Background & aim: Patients with end-stage liver disease require valid estimations of mortality for organ allocation and risk stratification. The model of end-stage liver disease (MELD) score is used for this purpose in most countries and incorporates
Publikováno v:
The Journal of nutritional biochemistry. 52
Apolipoprotein E (ApoE) plays a central role in lipid transport and cholesterol metabolism, with surplus cholesterol being removed from the liver through bile acid (BA) synthesis. Furthermore, BAs are of critical importance in fat absorption by formi
Autor:
J Borlak, Arun Kumar, Gerhard Liebisch, Prafull Kumar Singh, Philip G. Hewitt, Gerd Schmitz, Carsten Gnewuch
Publikováno v:
Reproductive Toxicology. 47:89-101
The calcium sensitizer and PDEIII inhibitor EMD82571 caused exencephaly, micrognathia, agnathia and facial cleft in 58% of fetuses. In pursue of mechanisms and to define adverse outcome pathways pregnant Wistar rats were dosed daily with either EMD82