Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Carsten Boesler"'
Autor:
Carsten Boesler, Norbert Rigo, Maria M. Anokhina, Marcel J. Tauchert, Dmitry E. Agafonov, Berthold Kastner, Henning Urlaub, Ralf Ficner, Cindy L. Will, Reinhard Lührmann
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The assembly of the splicesome involves several distinct stages that require the sequential action of DExD/H-box RNA helicases. Here, the authors uncover a new intermediate, the pre-B complex, that accumulates in the presence of an inactive form of t
Externí odkaz:
https://doaj.org/article/e7d1d18e40824533a67b9650add6c83c
Autor:
John L. Perez, Isabel Vogler, Evelyna Derhovanessian, Gábor Boros, David A. Cooper, Camila R. Fontes-Garfias, Kristen E. Pascal, Armin Schultz, Alexander Muik, Martin Bexon, Pei Yong Shi, Peter Koch, Ann Kathrin Eller, Verena Lörks, Mark Cutler, Daniel Maurus, Ludwig Heesen, Philip R. Dormitzer, Ugur Sahin, Kathrin U. Jansen, Manuel Tonigold, Jan Grützner, Azita J. Mahiny, Corinna Rosenbaum, Stefanie Bolte, Mathias Vormehr, Marie Cristine Kühnle, Sybille Baumann, Asaf Poran, Alexander Ulges, Alexandra Kemmer-Brück, Christos A. Kyratsous, Dirk Becker, Özlem Türeci, Alina Baum, Sebastian Brachtendorf, Lena M. Kranz, Carsten Boesler, Rolf Hilker, Tania Palanche, Julian Sikorski, Nicole Bidmon, Ulrich Luxemburger, David J. Langer, Jesse Z. Dong, Gábor Szabó, Jasmin Quandt, Katalin Karikó, Jonas Reinholz
Publikováno v:
Nature. 595:572-577
BNT162b2, a lipid nanoparticle (LNP) formulated nucleoside-modified messenger RNA (mRNA) that encodes the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike glycoprotein (S) stabilized in the prefusion conformation, has demonstrated 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0154147b441b18af735efb00657c62f
https://doi.org/10.1038/s41586-021-03653-6
https://doi.org/10.1038/s41586-021-03653-6
Autor:
Rolf Hilker, Jasmin Quandt, Boris Fischer, Jan Grützner, Kena A. Swanson, Sebastian Brachtendorf, Julian Sikorski, Mark Cutler, Kristen E. Pascal, Alexandra Kemmer-Brück, Lena M. Kranz, Dirk Becker, Katalin Karikó, Philip R. Dormitzer, Corinna Rosenbaum, Ulrich Luxemburger, Tania Palanche, Ugur Sahin, Camila R. Fontes-Garfias, Özlem Türeci, David A. Cooper, Armin Schultz, Alexander Muik, Ingrid L. Scully, Marie Cristine Kühnle, Jakob Loschko, Pei Yong Shi, Warren Kalina, Daniel Maurus, Verena Lörks, David J. Langer, Stefanie Bolte, Isabel Vogler, Mathias Vormehr, Christos A. Kyratsous, Carsten Boesler, Ann Kathrin Eller, Martin Bexon, Alina Baum, John L. Perez, Kathrin U. Jansen, Evelyna Derhovanessian
Publikováno v:
Nature
An effective vaccine is needed to halt the spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic. Recently, we reported safety, tolerability and antibody response data from an ongoing placebo-controlled, observer-blinded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e759c17cfd365c57e05fc7d355e9a4f
https://doi.org/10.1038/s41586-020-2814-7
https://doi.org/10.1038/s41586-020-2814-7
Autor:
Warren Kalina, Evelyna Derhovanessian, David J. Langer, Alexander Muik, Jakob Loschko, Kristen E. Pascal, Daniel Maurus, Corinna Rosenbaum, Katalin Karikó, Mark Cutler, Stefanie Bolte, Armin Schultz, Christos A. Kyratsous, Isabel Vogler, Ingrid L. Scully, Ann Kathrin Eller, Dirk Becker, David A. Cooper, Jan Grützner, Pei Yong Shi, Julian Sikorski, Tania Palanche, Martin Bexon, Alexandra Kemmer-Brück, Rolf Hilker, Ulrich Luxemburger, Kathrin U. Jansen, Mathias Vormehr, Philip R. Dormitzer, Verena Lörks, Sebastian Brachtendorf, Lena M. Kranz, John L. Perez, Marie Cristine Kühnle, Jasmin Quandt, Boris Fischer, Kena A. Swanson, Özlem Türeci, Ugur Sahin, Camila R. Fontes-Garfias, Carsten Boesler, Alina Baum
Publikováno v:
Nature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a440c230522e2d8f68ee1727420d6386
Autor:
Kristen E. Pascal, Jasmin Quandt, Boris Fischer, Verena L Loerks, Corinna Rosenbaum, Kena A. Swanson, David J. Langer, Oezlem Tuereci, Katalin Karikó, Carsten Boesler, Stefanie Bolte, Kathrin U. Jansen, Ugur Sahin, Julian Sikorski, Daniel Maurus, Alina Baum, Armin Schultz, Philip R. Dormitzer, Christos A. Kyratsous, Ingrid L. Scully, Pei Yong Shi, Dirk Becker, Ulrich Luxemburger, Mark Cutler, Rolf Hilker, David A. Cooper, Sebastian Brachtendorf, Lena M. Kranz, Alexandra Kemmer-Brueck, Isabel Vogler, Alexander Muik, Martin Bexon, Jakob Loschko, John L. Perez, Mathias Vormehr, Tania Palanche, Ann-Kathrin Eller, Marie-Cristine Kuehnle, Warren Kalina, Evelyna Derhovanessian, Camila R. Fontes-Garfias, Jan Gruetzner
An effective vaccine is needed to halt the spread of the SARS-CoV-2 pandemic. Recently, we reported safety, tolerability and antibody response data from an ongoing placebo-controlled, observer-blinded phase 1/2 COVID-19 vaccine trial with BNT162b1, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1454e40303d144ca37fcfc60bdb1bf4
Autor:
Henning Urlaub, Maria Anokhina, Dmitry E. Agafonov, Norbert Rigo, Ralf Ficner, Berthold Kastner, Carsten Boesler, Cindy L. Will, Reinhard Lührmann, Marcel J. Tauchert
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The precise role of the spliceosomal DEAD-box protein Prp28 in higher eukaryotes remains unclear. We show that stable tri-snRNP association during pre-catalytic spliceosomal B complex formation is blocked by a dominant-negative hPrp28 mutant lacking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5cc982b6462a9ad3610572e134f074c
http://resolver.sub.uni-goettingen.de/purl?gs-1/13548
http://resolver.sub.uni-goettingen.de/purl?gs-1/13548
Autor:
Cindy L. Will, Reinhard Lührmann, Henning Urlaub, Carsten Boesler, Norbert Rigo, Berthold Kastner, Dmitry E. Agafonov
Publikováno v:
RNA
Exon definition is the predominant initial spliceosome assembly pathway in higher eukaryotes, but it remains much less well-characterized compared to the intron-defined assembly pathway. Addition in trans of an excess of 5′ss containing RNA to a sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46680bf63a98f9cf5feaf079ca49c620
https://pubmed.ncbi.nlm.nih.gov/26385511
https://pubmed.ncbi.nlm.nih.gov/26385511
The amoeba Dictyostelium discoideum is a well established model organism for studying numerous aspects of cellular and developmental functions. Its ribosomal RNA (rRNA) is encoded in an extrachromosomal palindrome that exists in ∼100 copies in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c82c0d9474093c12f911bdf12dc73c6
https://europepmc.org/articles/PMC3093845/
https://europepmc.org/articles/PMC3093845/