Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Carsten Berges"'
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Allogeneic hematopoietic stem cell transplantation is the only curative treatment option for several hematological malignancies and immune deficiency syndromes. Nevertheless, the development of a graft-versus-host disease (GvHD) after transplantation
Externí odkaz:
https://doaj.org/article/dc2a09bd52f1438aa33ed4a4a0534bfc
Publikováno v:
Molecules, Vol 17, Iss 12, Pp 14685-14699 (2012)
The well-known Ugi reaction of aldehydes with amines, carboxylic acids and isocyanides leads to the formation of acyclic α-acylaminocarboxamides. Replacement of the carboxylic acid derivatives with β-acyl substituted acrylic acids gives access to h
Externí odkaz:
https://doaj.org/article/aa04e6decc134a8fb9f204a15e426748
Publikováno v:
Immunologic Research. 64:687-698
Acute graft-versus-host disease (aGvHD) is still a major cause of transplant-related mortality after allogeneic stem cell transplantation (ASCT). It requires immunosuppressive treatments that broadly abrogate T cell responses including beneficial one
Autor:
Jonathan Schupp, Jennifer Schultze, Nikolas K. Haass, Janine Schlöder, Kaloian Koynov, Henning Weiss, Sven Kurch, Helmut Jonuleit, Andrea Tuettenberg, Markus Mezger, Wolfgang Tremel, Carsten Berges, Arne Kienzle, Svenja Winzen, Robert Ose, Meike Schinnerer
Publikováno v:
Advanced Healthcare Materials. 6
Publikováno v:
International Journal of Molecular Sciences; Volume 18; Issue 2; Pages: 271
Multiple sclerosis (MS) is a chronic autoimmune disease caused by an insufficient suppression of autoreactive T lymphocytes. One reason for the lack of immunological control is the reduced responsiveness of T effector cells (Teff) for the suppressive
Autor:
Carsten, Berges, Thomas, Kerkau, Sandra, Werner, Nelli, Wolf, Nadine, Winter, Thomas, Hünig, Hermann, Einsele, Max S, Topp, Niklas, Beyersdorf
Publikováno v:
Immunity, Inflammation and Disease
Introduction For many patients with leukemia only allogeneic bone marrow transplantion provides a chance of cure. Co‐transplanted mature donor T cells mediate the desired Graft versus Tumor (GvT) effect required to destroy residual leukemic cells.
Publikováno v:
Biologie in unserer Zeit. 38:168-174
Das Ubiquitin-Proteasom-System ist eines der wichtigsten zellularen Regulationssysteme. In weniger als 25 Jahren wurde es systematisch und vollstandig charakterisiert. Heute bietet es eine umfassende molekulare Basis fur die Therapie bosartiger, entz
Autor:
Heinrich Haberstock, Volker Daniel, Mahmoud Sadeghi, Carsten Berges, Dominik Fuchs, Cord Naujokat, Marion Miltz, Gerhard Opelz
Publikováno v:
Immunology. 124:234-246
The proteasome constitutes the central proteolytic component of the highly conserved ubiquitin-proteasome system, which is required for the maintenance and regulation of basic cellular processes, including differentiation, proliferation, cell cycling
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1773:1389-1397
The highly conserved ubiquitin–proteasome system is the principal machinery for extralysosomal protein degradation in eukaryotic cells. The 26S proteasome, a large multicatalytic multisubunit protease that processes cell proteins by limited and con
Publikováno v:
Transplantation. 83:485-497
BACKGROUND The polyclonal rabbit antithymocyte and anti-T-cell immunoglobulins (ATGs) Thymoglobulin (TG) and ATG-Fresenius S (ATG-F) have been widely used for the prevention and therapy of allograft rejection and graft versus host disease in transpla