Zobrazeno 1 - 10
of 292
pro vyhledávání: '"Carsten B Schmidt-Weber"'
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0259914 (2021)
In real life, humans are exposed to whole pollen grains at the air epithelial barrier. We developed a system for in vitro dosing of whole pollen grains at the Air-Liquid Interface (ALI) and studied their effect on the immortalized human bronchial epi
Externí odkaz:
https://doaj.org/article/7cc60923349d4046b961c4eca45b762e
Autor:
Anna-Lena Geiselhöringer, Daphne Kolland, Arisha Johanna Patt, Linda Hammann, Amelie Köhler, Luisa Kreft, Nina Wichmann, Miriam Hils, Christiane Ruedl, Marc Riemann, Tilo Biedermann, David Anz, Andreas Diefenbach, David Voehringer, Carsten B. Schmidt-Weber, Tobias Straub, Maria Pasztoi, Caspar Ohnmacht
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Dendritic cells (DCs) are crucial for initiating protective immune responses and have also been implicated in the generation and regulation of Foxp3+ regulatory T cells (Treg cells). Here, we show that in the lamina propria of the small inte
Externí odkaz:
https://doaj.org/article/4cfef856783040f8968990d1cb8edde1
Autor:
Antonio Aguilar-Pimentel, Anke Graessel, Francesca Alessandrini, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Dennis Russkamp, Adam Chaker, Markus Ollert, Simon Blank, Jan Gutermuth, Carsten B Schmidt-Weber
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178563 (2017)
Allergen-specific immunotherapy (AIT) is the only curative treatment for type-1 allergies, but sometimes shows limited therapeutic response as well as local and systemic side effects. Limited control of local inflammation and patient symptoms hampers
Externí odkaz:
https://doaj.org/article/5e4f609812d2479e9eafcd871cbbd527
Autor:
Evelyn Schneider, Yacine Amar, Katja Butter, Katja Steiger, Stephanie Musiol, Manuel Garcia-Käufer, Inga Marie Hölge, Benjamin Schnautz, Silvia Gschwendtner, Andrea Ghirardo, Richard Gminski, Bernadette Eberlein, Julia Esser von Bieren, Tilo Biedermann, Stefan Haak, Martin Ohlmeyer, Carsten B. Schmidt-Weber, Stefanie Eyerich, Francesca Alessandrini
Publikováno v:
Environment International, Vol 192, Iss , Pp 109035- (2024)
Pinewood, increasingly used in construction and interior fittings, emits high amounts of volatile organic compounds (VOCs), which tend to accumulate in indoor air. Whether indoor VOCs affect the development of atopic dermatitis (AD) is a matter of de
Externí odkaz:
https://doaj.org/article/8a82eb47bdf24aeb8e7e4d0f66c7b79b
Autor:
Maria Quaranta, Stefanie Eyerich, Bettina Knapp, Francesca Nasorri, Claudia Scarponi, Martina Mattii, Natalie Garzorz, Anna T Harlfinger, Teresa Jaeger, Martine Grosber, Davide Pennino, Martin Mempel, Christina Schnopp, Fabian J Theis, Cristina Albanesi, Andrea Cavani, Carsten B Schmidt-Weber, Johannes Ring, Kilian Eyerich
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101814 (2014)
Psoriasis is characterized by an apoptosis-resistant and metabolic active epidermis, while a hallmark for allergic contact dermatitis (ACD) is T cell-induced keratinocyte apoptosis. Here, we induced ACD reactions in psoriasis patients sensitized to n
Externí odkaz:
https://doaj.org/article/4b174f302fb14f9f952431eeeaa8e6ee
Autor:
Johannes Grosch, Bernadette Eberlein, Sebastian Waldherr, Mariona Pascal, Britta Dorn, Clara San Bartolomé, Federico De La Roca Pinzón, Maximilian Schiener, Ulf Darsow, Tilo Biedermann, Jonas Lidholm, Maria Beatrice Bilò, Thilo Jakob, Carsten B. Schmidt-Weber, Simon Blank
Publikováno v:
Toxins, Vol 16, Iss 11, p 498 (2024)
Sensitization to cross-reactive allergens complicates identifying the culprit insect in Hymenoptera venom allergy via diagnostic tests. This study evaluates sensitization to hyaluronidases (Api m 2 from honey bee (Apis mellifera) venom, HBV; Pol d 2
Externí odkaz:
https://doaj.org/article/dbab6879640c47e9aaf3b272aae159c8
Autor:
Pierre-Yves Mantel, Harmjan Kuipers, Onur Boyman, Claudio Rhyner, Nadia Ouaked, Beate Rückert, Christian Karagiannidis, Bart N Lambrecht, Rudolf W Hendriks, Reto Crameri, Cezmi A Akdis, Kurt Blaser, Carsten B Schmidt-Weber
Publikováno v:
PLoS Biology, Vol 5, Iss 12, p e329 (2007)
Transcription factors act in concert to induce lineage commitment towards Th1, Th2, or T regulatory (Treg) cells, and their counter-regulatory mechanisms were shown to be critical for polarization between Th1 and Th2 phenotypes. FOXP3 is an essential
Externí odkaz:
https://doaj.org/article/03963e8e757c468da3c9f6952ff93200
Autor:
Sonja Heine, Francesca Alessandrini, Johannes Grosch, Carina Graß, Alexander Heldner, Benjamin Schnautz, Johanna Grosch, Jeroen Buters, Benjamin O. Slusarenko, Daniel Krappmann, Francesca Fallarino, Caspar Ohnmacht, Carsten B. Schmidt-Weber, Simon Blank
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundAllergen-specific immunotherapy (AIT) is able to restore immune tolerance to allergens in allergic patients. However, some patients do not or only poorly respond to current treatment protocols. Therefore, there is a need for deeper mechanis
Externí odkaz:
https://doaj.org/article/fe94fdc4bd5542aab76f32ed88e01c5d
Autor:
Ann-Marie Maier, Karsten Huth, Francesca Alessandrini, Fiona Henkel, Benjamin Schnautz, Anela Arifovic, Fabien Riols, Mark Haid, Anja Koegler, Katrin Sameith, Carsten B. Schmidt-Weber, Julia Esser-von-Bieren, Caspar Ohnmacht
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/1bba138179a24574a574047fc20a89fb
Autor:
Ann-Marie Maier, Karsten Huth, Francesca Alessandrini, Fiona Henkel, Benjamin Schnautz, Anela Arifovic, Fabien Riols, Mark Haid, Anja Koegler, Katrin Sameith, Carsten B. Schmidt-Weber, Julia Esser-von-Bieren, Caspar Ohnmacht
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Allergic inflammation of the airways such as allergic asthma is a major health problem with growing incidence world-wide. One cardinal feature in severe type 2-dominated airway inflammation is the release of lipid mediators of the eicosanoid family t
Externí odkaz:
https://doaj.org/article/a132a1e60ce440eea344aaf3afe6ac7f