Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Carsten Culmsee"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 8, Pp 1-12 (2024)
Abstract Mitochondria are highly dynamic organelles which undergo constant fusion and fission as part of the mitochondrial quality control. In genetic diseases and age-related neurodegenerative disorders, altered mitochondrial fission-fusion dynamics
Externí odkaz:
https://doaj.org/article/0ee62282a2e54ecda2b8cc09fa06f8dd
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/caa87cb6375a41e49852201ae4a5f181
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Polypharmacy is common among patients with antithrombotic medication, giving rise to concerns about Drug-Related Problems (DRPs). Therefore, these patients would benefit from a Medication Review (MR) along with pharmacist counselling to reduce the ri
Externí odkaz:
https://doaj.org/article/02a66d13c5b8411f91f4423fbb7f3d51
Autor:
Wei Han, Eva-Maria Meißner, Stefanie Neunteibl, Madeline Günther, Jörg Kahnt, Amalia Dolga, Cuicui Xie, Nikolaus Plesnila, Changlian Zhu, Klas Blomgren, Carsten Culmsee
Publikováno v:
Cell Death and Disease, Vol 14, Iss 3, Pp 1-11 (2023)
Summary Neural stem and progenitor cell (NSPC) transplants provide neuroprotection in models of acute brain injury, but the underlying mechanisms are not fully understood. Here, we provide evidence that caspase-dependent apoptotic cell death of NSPCs
Externí odkaz:
https://doaj.org/article/83f1e396304f48eb9d728d896a1d6a89
Autor:
Florian Schindler, Timo Schinkoethe, Sven Mahner, Thomas Kolben, Rachel Wuerstlein, Carsten Culmsee, Nadia Harbeck, Tanja K. Eggersmann
Publikováno v:
Therapeutic Advances in Drug Safety, Vol 14 (2023)
Background: Modern oral antineoplastic and immune-modulating drugs offer an array of therapeutic advantages, and yet pose challenges in daily use for patients, physicians and pharmacists. In contrast to intravenous administration, these drugs are not
Externí odkaz:
https://doaj.org/article/5cc9960574534755b9dd798a7f3e2185
Autor:
Madeline Günther, Peter Schnierle, Thorsten Rose, Jonathan Schlegel, Georg Boonen, Jürgen Drewe, Eduardo Muñoz, Bernd L. Fiebich, Carsten Culmsee
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 393 (2024)
Cimicifuga racemosa extracts (CREs) have gained well-established use for the treatment of menopausal symptoms such as hot flushes and excessive sweating, and weight gain. While the clinical effects of CREs have been well documented, the mechanisms un
Externí odkaz:
https://doaj.org/article/c3416edf27ab48769dd4450a78b86212
Autor:
Madeline Günther, Samentha Dabare, Jennifer Fuchs, Sandra Gunesch, Julian Hofmann, Michael Decker, Carsten Culmsee
Publikováno v:
Antioxidants, Vol 13, Iss 1, p 44 (2023)
Cinnamic acid, ferulic acid, and the flavonoids quercetin and taxifolin (dihydroquercetin) are naturally occurring compounds found in plants. They are often referred to as polyphenols and are known, among others, for their pharmacological effects sup
Externí odkaz:
https://doaj.org/article/7f6bb55a2448400eb8f6cd2311832146
Autor:
Melanie Merkel, Bjarne Goebel, Moritz Boll, Aasha Adhikari, Viktoria Maurer, Dieter Steinhilber, Carsten Culmsee
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1590 (2023)
Ferroptosis is a form of oxidative cell death that is characterized by enhanced lipid peroxidation and mitochondrial impairment. The enzymes acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase (LPCAT) pl
Externí odkaz:
https://doaj.org/article/1792ec0e9c5948659abba7dfd4a872e5
Autor:
Lena Hoffmann, Marcel S. Waclawczyk, Stephan Tang, Eva-Maria Hanschmann, Manuela Gellert, Marco B. Rust, Carsten Culmsee
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-13 (2021)
Abstract Many cell death pathways, including apoptosis, regulated necrosis, and ferroptosis, are relevant for neuronal cell death and share common mechanisms such as the formation of reactive oxygen species (ROS) and mitochondrial damage. Here, we pr
Externí odkaz:
https://doaj.org/article/e23bdc3146454104a8cb6b7d540c28e4
Autor:
Antonia Clarissa Wehn, Igor Khalin, Marco Duering, Farida Hellal, Carsten Culmsee, Peter Vandenabeele, Nikolaus Plesnila, Nicole Angela Terpolilli
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-18 (2021)
Abstract Traumatic brain injury (TBI) causes acute and subacute tissue damage, but is also associated with chronic inflammation and progressive loss of brain tissue months and years after the initial event. The trigger and the subsequent molecular me
Externí odkaz:
https://doaj.org/article/a7508595efbf478288b4b0d810f4d914