Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Carsten, Krantz"'
Autor:
Ian Robinson, Simon Moore, Jo Kilgour, Sidney Mukaratirwa, Mark Price, David Jones, Annick Cauvin, Carsten Krantz, Mark C Freke, Andrew Allen, Alison Wolfreys, Jeffrey S Tepper, Scott Manetz, Sherri Dudal, George Karantabias
Publikováno v:
Toxicologic pathology. 49(2)
The inhaled route is still a relatively novel route for delivering biologics and poses additional challenges to those encountered with inhaled small molecules, further complicating the design and interpretation of toxicology studies. A working group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b786789bd9a095944ef7cb606fe84aff
https://pubmed.ncbi.nlm.nih.gov/33535023
https://pubmed.ncbi.nlm.nih.gov/33535023
Autor:
Surinder Kaur, Susan Spitz, Jan Welink, Fabio Garofolo, John Kadavil, Christopher P. Evans, Jianing Zeng, Shaolian Zhou, Laurent Cocea, Linzhi Chen, Timothy V Olah, Kara Scheibner, Ronald Bauer, An Song, Carsten Krantz, Mark Bustard, Jason Wakelin-Smith, Nicola Hughes, Yoshiro Saito, Keyang Xu, Lorella Di Donato, Barry R Jones, Rafiq Islam, Joe Palandra, Stephanie Croft, Akiko Ishii-Watabe, Sam Haidar, Anita Lee, Ludovicus Staelens, Nilufer Tampal, João Pedras-Vasconcelos, Fabrizio Galliccia, Natasha Savoie, Jeff Duggan, Eric Thomas, Stephen Vinter, Gustavo Mendes Lima Santos
Publikováno v:
Bioanalysis. 8:2457-2474
The 2016 10th Workshop on Recent Issues in Bioanalysis (10th WRIB) took place in Orlando, Florida with participation of close to 700 professionals from pharmaceutical/biopharmaceutical companies, biotechnology companies, contract research organizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fb35a664f83e035f78e6f60a0e830b
https://doi.org/10.4155/bio-2016-4988
https://doi.org/10.4155/bio-2016-4988
Autor:
Meike Scharenberg, Serge Côté, Carsten Krantz, Craig T. Basson, Keith DiPetrillo, Stefan Ewert, Janeen M Salter, Brian Stoll, Geraldine Horny, Simone Schleeger, Yu-Hsin Chiu, Julie DeGagne, Peter Hoffmann, Andreas Hein, Jianying Yu, Peter McCormack, Zhiping Chen, Paul Ramage, Nikolaus Schiering, Frederic Villard, Yasser Khder, Samu Melkko, Jörg Eder, Ulrich Hassiepen, Yiming Zhang, Lionel Muller, Xueming Huang, Robert J. A. Frost, Kenneth Kulmatycki, Alexander W. Koch, David Louis Feldman
Publikováno v:
Blood. 133(13)
A large unmet medical need exists for safer antithrombotic drugs because all currently approved anticoagulant agents interfere with hemostasis, leading to an increased risk of bleeding. Genetic and pharmacologic evidence in humans and animals suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f8d1cd3f39c4c75c6b009bf317a08d
https://pubmed.ncbi.nlm.nih.gov/30923107
https://pubmed.ncbi.nlm.nih.gov/30923107
Autor:
Carsten Krantz, Morty Razavi, Andrew Paul Warren, Richard Yip, Simon Meier, N. Leigh Anderson, Terry W. Pearson, Filip K Sucharski, Christian Miess, Matthew E. Pope
Publikováno v:
Bioanalysis. 10(13)
Aim: Hybrid LC–MS/MS assays are increasingly used to quantitate proteins in biological matrices. These assays involve analyte enrichment at the protein level. Although suitability has been demonstrated, they are limited by the lack of appropriate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12cd3a7512d99855abd3dd43ab604a5e
https://pubmed.ncbi.nlm.nih.gov/29972312
https://pubmed.ncbi.nlm.nih.gov/29972312
Autor:
Peter Lloyd, Andrej Skerjanec, Sherri Dudal, A Cordier, Jennifer Sims, Stewart Jones, Sarah Taplin, Carsten Krantz, Aline Piequet, G Jarai, Frank R. Brennan, Thierry Flandre, Andrew Paul Warren, K Subramanian, M Duval, J-C Genin, WS Law, G Van Heeke, Philip J. Lowe
Publikováno v:
mAbs. 7:829-837
QBP359 is an IgG1 human monoclonal antibody that binds with high affinity to human CCL21, a chemokine hypothesized to play a role in inflammatory disease conditions through activation of resident CCR7-expressing fibroblasts/myofibroblasts. The pharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15e2f7cb75d37828b9cacf97a7bcd18
https://doi.org/10.1080/19420862.2015.1060384
https://doi.org/10.1080/19420862.2015.1060384
Autor:
Sherri Dudal, Christian Miess, Wai Siang Law, Gwenola Treton, Jean-Christophe Genin, Peter Lloyd, Andrew Paul Warren, Carsten Krantz
Publikováno v:
Bioanalysis. 6:3225-3235
Background: The fully human monoclonal antibody mAb123, which binds to and neutralizes chemokine motif ligand-21 (CCL21) displays a faster clearance in cynomolgus monkey compared with typical IgG kinetics. A direct and an immunoaffinity LC–MS/MS as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3fb8797e348290a77763ff61c149b2
https://doi.org/10.4155/bio.14.167
https://doi.org/10.4155/bio.14.167
Autor:
Carsten Krantz, Jimmy Flarakos, Arlette Garnier, Hui Lin, Francis L. S. Tse, Wenkui Li, Xinliu Gao
Publikováno v:
Bioanalysis. 8(5)
Aim: Factor P (Properdin), an endogenous glycoprotein, plays a key role in innate immune defense. Its quantification is important for understanding the pharmacodynamics (PD) of drug candidate(s). Results: In the present work, an immunoaffinity captur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6229e5bab9e2b8a78c141ecf97c62d44
https://pubmed.ncbi.nlm.nih.gov/26891810
https://pubmed.ncbi.nlm.nih.gov/26891810
Autor:
Michael Bahr, Andreas Striebinger, Ulrich Ebert, John E. Harlan, Eve H. Barlow, Patrick Keller, Heinz Hillen, Carsten Krantz, Volker Nimmrich, Bodo Janson, Stefan Barghorn, Robert S. Bitner, Martin Schmidt
Publikováno v:
Journal of Neurochemistry. 95:834-847
Amyloid b-peptide (Ab)1)42 oligomers have recently been discussed as intermediate toxic species in Alzheimer’s disease (AD) pathology. Here we describe a new and highly stable Ab1)42 oligomer species which can easily be prepared in vitro and is pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64f5af21a80973eb18cd6911a3aecdef
https://doi.org/10.1111/j.1471-4159.2005.03407.x
https://doi.org/10.1111/j.1471-4159.2005.03407.x
Autor:
Lothar Brecker, Carsten Krantz, Gerald Wagner, Jean-Luc Mieusset, Vladimir B. Arion, Udo H. Brinker
Publikováno v:
Organic letters. 11(14)
Phenyl azide (1) has been encapsulated within cavitand 2 to form a 1:1 complex of 1@2 in the solid state. Subsequent irradiation affords two diastereomeric nitrene addition products 5 and 7. The ratio of 5 and 7 can be reversed by thermally induced v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f7499a253496783389bead46622d79
https://pubmed.ncbi.nlm.nih.gov/19537769
https://pubmed.ncbi.nlm.nih.gov/19537769
Autor:
Stefan, Barghorn, Volker, Nimmrich, Andreas, Striebinger, Carsten, Krantz, Patrick, Keller, Bodo, Janson, Michael, Bahr, Martin, Schmidt, Robert S, Bitner, John, Harlan, Eve, Barlow, Ulrich, Ebert, Heinz, Hillen
Publikováno v:
Journal of neurochemistry. 95(3)
Amyloid beta-peptide (Abeta)(1-42) oligomers have recently been discussed as intermediate toxic species in Alzheimer's disease (AD) pathology. Here we describe a new and highly stable Abeta(1-42) oligomer species which can easily be prepared in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0e8fcdf6e572438f4403267bb9fb8cd7
https://pubmed.ncbi.nlm.nih.gov/16135089
https://pubmed.ncbi.nlm.nih.gov/16135089