Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Carsten, Grüllich"'
Autor:
Hweixian Leong Penny, Kelly Hainline, Nathaniel Theoharis, Bin Wu, Christian Brandl, Christian Webhofer, Mason McComb, Sabine Wittemer-Rump, Gökben Koca, Sabine Stienen, Ralf C. Bargou, Horst-Dieter Hummel, Wolfgang Loidl, Carsten Grüllich, Tobias Eggert, Ben Tran, Daniel T. Mytych
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn oncology, anti-drug antibody (ADA) development that significantly curtails response durability has not historically risen to a level of concern. The relevance and attention ascribed to ADAs in oncology clinical studies have therefore b
Externí odkaz:
https://doaj.org/article/212fa5cf8e9f4350b4b25e8f215a32d7
Autor:
Elizabeth Alwers, Lina Jansen, Hendrik Bläker, Matthias Kloor, Katrin E. Tagscherer, Wilfried Roth, Daniel Boakye, Esther Herpel, Carsten Grüllich, Jenny Chang‐Claude, Hermann Brenner, Michael Hoffmeister
Publikováno v:
Molecular Oncology, Vol 14, Iss 2, Pp 363-372 (2020)
Previous studies have reported conflicting results regarding the benefit of administering 5‐FU‐based chemotherapy to colon cancer (CC) patients with microsatellite‐instable (MSI‐high) tumors, and results from stage‐specific analyses are sca
Externí odkaz:
https://doaj.org/article/aba6a658fd804e7c9782ae6395d1db61
Autor:
Gregor Warsow, Daniel Hübschmann, Kortine Kleinheinz, Cathleen Nientiedt, Martina Heller, Laura Van Coile, Yanis Tolstov, Lukas Trennheuser, Kathrin Wieczorek, Carine Pecqueux, Claudia Gasch, Timur Kuru, Joanne Nyarangi-Dix, Gencay Hatiboglu, Dogu Teber, Sven Perner, Albrecht Stenzinger, Wilfried Roth, Boris Hadaschik, Sascha Pahernik, Dirk Jäger, Carsten Grüllich, Anette Duensing, Roland Eils, Matthias Schlesner, Holger Sültmann, Markus Hohenfellner, Stefan Duensing
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract A venous tumor thrombus (VTT) is a potentially lethal complication of renal cell carcinoma (RCC) but virtually nothing is known about the underlying natural history. Based on our observation that venous thrombi contain significant numbers of
Externí odkaz:
https://doaj.org/article/fdc0109087c648f893b957962fedc3ad
Autor:
Cathleen Nientiedt, Martina Heller, Volker Endris, Anna-Lena Volckmar, Stefanie Zschäbitz, María A. Tapia-Laliena, Anette Duensing, Dirk Jäger, Peter Schirmacher, Holger Sültmann, Albrecht Stenzinger, Markus Hohenfellner, Carsten Grüllich, Stefan Duensing
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Mutations in BRCA1 or BRCA2 define a subset of prostate cancer patients. Herein, we address the question whether BRCA1/2 mutations have a predictive impact on chemotherapy with docetaxel, a widely used drug in patients with metastatic castra
Externí odkaz:
https://doaj.org/article/b15be919d5ff42faabf1b34d60384950
Autor:
Rouven Hoefflin, Bernd Lahrmann, Gregor Warsow, Daniel Hübschmann, Cathleen Spath, Britta Walter, Xin Chen, Luisa Hofer, Stephan Macher-Goeppinger, Yanis Tolstov, Nina Korzeniewski, Anette Duensing, Carsten Grüllich, Dirk Jäger, Sven Perner, Gita Schönberg, Joanne Nyarangi-Dix, Sanjay Isaac, Gencay Hatiboglu, Dogu Teber, Boris Hadaschik, Sascha Pahernik, Wilfried Roth, Roland Eils, Matthias Schlesner, Holger Sültmann, Markus Hohenfellner, Niels Grabe, Stefan Duensing
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
It has been increasingly recognised that tumours are not made up of a homogeneous population of cells. Here, the authors show heterogeneous expression of five protein markers in renal cell cancer and demonstrate that the progression of the tumour doe
Externí odkaz:
https://doaj.org/article/6b8b3ea588cd4746baa64e76cce15f72
Autor:
Xiaoguang Zhou, Jielin Li, Christina Marx, Yanis Tolstov, Geraldine Rauch, Esther Herpel, Stephan Macher-Goeppinger, Wilfried Roth, Carsten Grüllich, Sascha Pahernik, Markus Hohenfellner, Stefan Duensing
Publikováno v:
Translational Oncology, Vol 8, Iss 6, Pp 480-486 (2015)
Renal cell carcinoma (RCC) is characterized by a profound disruption of proapoptotic signaling networks leading to chemo- and radioresistance. A key mediator of DNA damage-induced apoptosis is the BH3-only protein PUMA. Given its central role in proa
Externí odkaz:
https://doaj.org/article/8ca6f6c2dc57465ebe773b08a1d1f9a5
Autor:
Josef Mang, Nina Korzeniewski, Dimo Dietrich, Verena Sailer, Yanis Tolstov, Sam Searcy, Jost von Hardenberg, Sven Perner, Glen Kristiansen, Alexander Marx, Wilfried Roth, Esther Herpel, Carsten Grüllich, Valentin Popeneciu, Sascha Pahernik, Boris Hadaschik, Markus Hohenfellner, Stefan Duensing
Publikováno v:
Translational Oncology, Vol 8, Iss 6, Pp 487-496 (2015)
We have recently shown that centrosomal protein 57 (CEP57) is overexpressed in a subset of human prostate cancers. CEP57 is involved in intracellular transport processes, and its overexpression causes mitotic defects as well as abnormal microtubule n
Externí odkaz:
https://doaj.org/article/b04777fa3d1e4db79f8ebebf4641d25c
Autor:
Xiaoguang Zhou, Yanis Tolstov, Aysenur Arslan, Wilfried Roth, Carsten Grüllich, Sascha Pahernik, Markus Hohenfellner, Stefan Duensing
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 12, Pp 1028-1035 (2014)
Resistance to DNA damage–induced apoptosis is a hallmark of cancer and a major cause of treatment failure and lethal disease outcome. A tumor entity that is largely resistant to DNA-damaging therapies including chemo- or radiotherapy is renal cell
Externí odkaz:
https://doaj.org/article/20e077f4dadc4848b52147716c704cc2
Autor:
Thomas Gauler, Manfred Johannsen, Carsten Grüllich, Viktor Grünwald, Jens Bedke, Nils Kroeger, Philipp Ivanyi
Publikováno v:
Journal of Cancer Research and Clinical Oncology
This letter summarizes recommendations from the interdisciplinary working group of renal tumors (IAGN) of the German Cancer Society for the systemic treatment of advanced/metastatic renal cell carcinoma in the context of the current SARS-CoV-2 pandem
Autor:
Carsten Grüllich
Publikováno v:
Die Urologie ISBN: 9783642411687
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45fcabe752b695acbd617feb2db1bd11
https://doi.org/10.1007/978-3-642-41168-7_250-1
https://doi.org/10.1007/978-3-642-41168-7_250-1