Zobrazeno 1 - 10
of 469
pro vyhledávání: '"Carsten, Carlberg"'
Autor:
Ranjini Ghosh Dastidar, Julia Jaroslawska, Marjo Malinen, Tomi-Pekka Tuomainen, Jyrki K. Virtanen, Igor Bendik, Carsten Carlberg
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Vitamin D modulates innate and adaptive immunity, the molecular mechanisms of which we aim to understand under human in vivo conditions. Therefore, we designed the study VitDHiD (NCT03537027) as a human investigation, in which 25 healthy ind
Externí odkaz:
https://doaj.org/article/6da6f992957342c4b2e5d9e476344c81
Autor:
Marek Gowkielewicz, Aleksandra Lipka, Wojciech Zdanowski, Tomasz Waśniewski, Marta Majewska, Carsten Carlberg
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Anti-Müllerian hormone (AMH) is a peptide belonging to the transforming growth factor beta superfamily and acts exclusively through its receptor type 2 (AMHR2). From the 8th week of pregnancy, AMH is produced by Sertoli cells, and from the 23rd week
Externí odkaz:
https://doaj.org/article/bc23fe89dfe54550b10ed39b86bc767a
Autor:
Shareefa A. AlGhamdi, Ranjini Ghosh Dastidar, Maciej Rybiński, Hadeil M. Alsufiani, Sawsan O. Khoja, Nusaibah N. Enaibsi, Safa F. Saif, Carsten Carlberg
Publikováno v:
Saudi Pharmaceutical Journal, Vol 32, Iss 8, Pp 102137- (2024)
The concept of the vitamin D response index was developed based on vitamin D intervention studies conducted with Finnish cohorts. In this study, we challenged the concept by performing a single vitamin D3 bolus (80,000 IU) intervention with a cohort
Externí odkaz:
https://doaj.org/article/c1d654408c9742c1b5acc24778e65897
Autor:
Lars-Oliver Klotz, Carsten Carlberg
Publikováno v:
Redox Biology, Vol 68, Iss , Pp 102920- (2023)
During our whole lifespan, from conception to death, the epigenomes of all tissues and cell types of our body integrate signals from the environment. This includes signals derived from our diet and the uptake of macro- and micronutrients. In most cas
Externí odkaz:
https://doaj.org/article/ff2045d785da4250abae06eac8f04202
Autor:
Eunike Velleuer, Elisa Domínguez-Hüttinger, Alfredo Rodríguez, Leonard A. Harris, Carsten Carlberg
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Fanconi anemia (FA) is a rare disease (incidence of 1:300,000) primarily based on the inheritance of pathogenic variants in genes of the FA/BRCA (breast cancer) pathway. These variants ultimately reduce the functionality of different proteins involve
Externí odkaz:
https://doaj.org/article/eaec3be227c84eb4b384da371bc68651
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102695- (2023)
Nutrigenomics attempts to characterize and integrate the relation between dietary molecules and gene expression on a genome-wide level. One of the biologically active nutritional compounds is vitamin D3, which activates via its metabolite 1α,25-dihy
Externí odkaz:
https://doaj.org/article/64fa6c1eb88245aebad30cff36fa8d42
Autor:
Carsten Carlberg
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102656- (2023)
Nutrigenomics describes the interaction between nutrients and our genome. Since the origin of our species most of these nutrient-gene communication pathways have not changed. However, our genome experienced over the past 50,000 years a number of evol
Externí odkaz:
https://doaj.org/article/4b5846781b5249ffa8555429a3bcaccd
Autor:
Carsten Carlberg, Marcin P. Mycko
Publikováno v:
Cells, Vol 12, Iss 19, p 2391 (2023)
Environmental triggers often work via signal transduction cascades that modulate the epigenome and transcriptome of cell types involved in the disease process. Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system bein
Externí odkaz:
https://doaj.org/article/cdb2d178f06b47c0919294939a80ea69
Autor:
Timothy Warwick, Marcel H. Schulz, Stefan Günther, Ralf Gilsbach, Antonio Neme, Carsten Carlberg, Ralf P. Brandes, Sabine Seuter
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The transcription factor vitamin D receptor (VDR) is the high affinity nuclear target of the biologically active form of vitamin D3 (1,25(OH)2D3). In order to identify pure genomic transcriptional effects of 1,25(OH)2D3, we used VDR cistrome
Externí odkaz:
https://doaj.org/article/cba2a41fe96a4a9f9401576c24fe4ce7