Knihovna AV ČR, v. v. i.
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Zobrazeno 1 - 10 of 39 pro vyhledávání: '"Carsten, Calaminus"'
1
Akademický článek
An IgG‐based bispecific antibody for improved dual targeting in PSMA‐positive cancer
Autor: Latifa Zekri, Fabian Vogt, Lukas Osburg, Stefanie Müller, Joseph Kauer, Timo Manz, Martin Pflügler, Andreas Maurer, Jonas S Heitmann, Ilona Hagelstein, Melanie Märklin, Sebastian Hörner, Tilmann Todenhöfer, Carsten Calaminus, Arnulf Stenzl, Bernd Pichler, Christian la Fougère, Marc A Schneider, Hans‐Georg Rammensee, Lars Zender, Bence Sipos, Helmut R Salih, Gundram Jung
Publikováno v: EMBO Molecular Medicine, Vol 13, Iss 2, Pp 1-15 (2020)
Abstract The prostate‐specific membrane antigen (PSMA) has been demonstrated in numerous studies to be expressed specifically on prostate carcinoma cells and on the neovasculature of several other cancer entities. However, the simultaneous expressi
Externí odkaz: https://doaj.org/article/c7fa60882d054b8bb603dab8b98336df
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2
Akademický článek
Cell motility and migration as determinants of stem cell efficacy
Autor: Lusine Danielyan, Matthias Schwab, Georg Siegel, Bianca Brawek, Olga Garaschuk, Nithi Asavapanumas, Marine Buadze, Ali Lourhmati, Hans-Peter Wendel, Meltem Avci-Adali, Marcel A. Krueger, Carsten Calaminus, Ulrike Naumann, Stefan Winter, Elke Schaeffeler, Annett Spogis, Sandra Beer-Hammer, Jonas J. Neher, Gabriele Spohn, Anja Kretschmer, Eva-Maria Krämer-Albers, Kerstin Barth, Hong Jun Lee, Seung U. Kim, William H. Frey, II, Claus D. Claussen, Dirk M. Hermann, Thorsten R. Doeppner, Erhard Seifried, Christoph H. Gleiter, Hinnak Northoff, Richard Schäfer
Publikováno v: EBioMedicine, Vol 60, Iss , Pp 102989- (2020)
Background: Stem cells` (SC) functional heterogeneity and its poorly understood aetiology impedes clinical development of cell-based therapies in regenerative medicine and oncology. Recent studies suggest a strong correlation between the SC migration
Externí odkaz: https://doaj.org/article/50fadaeaeb26482dbe9ab2d00b7b2fef
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3
Akademický článek
Modulating endothelial adhesion and migration impacts stem cell therapies efficacy
Autor: Richard Schäfer, Matthias Schwab, Georg Siegel, Andreas von Ameln-Mayerhofer, Marine Buadze, Ali Lourhmati, Hans-Peter Wendel, Torsten Kluba, Marcel A. Krueger, Carsten Calaminus, Eva Scheer, Massimo Dominici, Giulia Grisendi, Thorsten R. Doeppner, Jana Schlechter, Anne Kathrin Finzel, Dominic Gross, Roland Klaffschenkel, Frank K. Gehring, Gabriele Spohn, Anja Kretschmer, Karen Bieback, Eva-Maria Krämer-Albers, Kerstin Barth, Anne Eckert, Stefanie Elser, Joerg Schmehl, Claus D. Claussen, Erhard Seifried, Dirk M. Hermann, Hinnak Northoff, Lusine Danielyan
Publikováno v: EBioMedicine, Vol 60, Iss , Pp 102987- (2020)
Background: Limited knowledge of stem cell therapies` mechanisms of action hampers their sustainable implementation into the clinic. Specifically, the interactions of transplanted stem cells with the host vasculature and its implications for their th
Externí odkaz: https://doaj.org/article/cfdc3c5617b54f99af3c86514beec666
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4
Data from PI3K Pathway Inhibition Achieves Potent Antitumor Activity in Melanoma Brain Metastases In Vitro and In Vivo
Autor: Friedegund Meier, Dana Westphal, Dagmar Kulms, Bernd J. Pichler, Keith Flaherty, Reinhard Dummer, Gustavo B. Baretton, Matthias Meinhardt, Michael H. Muders, Gabriele Schackert, Stefan Beissert, Christian Praetorius, Marion Mai, Benjamin Bender, Leticia Quintanilla-Fend, Birgit Schittek, Claus Garbe, Thomas K. Eigentler, Benjamin Weide, Tobias Sinnberg, Carsten Calaminus, Andreas M. Schmid, Ghazaleh Tabatabai, Jennifer Schmitz, Heike Niessner
Purpose: Great advances have recently been made in treating patients with metastatic melanoma. However, existing therapies are less effective on cerebral than extracerebral metastases. This highlights the potential role of the brain environment on tu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422a064b5a277c0d06d2068e362f2585
https://doi.org/10.1158/1078-0432.c.6526376
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5
Supplementary Figures 1_9 from PI3K Pathway Inhibition Achieves Potent Antitumor Activity in Melanoma Brain Metastases In Vitro and In Vivo
Autor: Friedegund Meier, Dana Westphal, Dagmar Kulms, Bernd J. Pichler, Keith Flaherty, Reinhard Dummer, Gustavo B. Baretton, Matthias Meinhardt, Michael H. Muders, Gabriele Schackert, Stefan Beissert, Christian Praetorius, Marion Mai, Benjamin Bender, Leticia Quintanilla-Fend, Birgit Schittek, Claus Garbe, Thomas K. Eigentler, Benjamin Weide, Tobias Sinnberg, Carsten Calaminus, Andreas M. Schmid, Ghazaleh Tabatabai, Jennifer Schmitz, Heike Niessner
Figure S1: The PI3K inhibitor buparlisib inhibits AKT phosphorylation and cell growth and induces cell cycle arrest and apoptosis in BRAF-mutant metastatic melanoma cell lines Figure S2: The PI3K inhibitor buparlisib inhibits AKT phosphorylation and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb88d76d1d5fd4277e22deb79ba1373
https://doi.org/10.1158/1078-0432.22466615
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6
Akademický článek
Olfactory neuron-specific expression of A30P alpha-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages
Autor: Silke Nuber, Elisabeth Petrasch-Parwez, Oscar Arias-Carrión, Leanie Koch, Zacharias Kohl, Jacqueline Schneider, Carsten Calaminus, Rolf Dermietzel, Anna Samarina, Jana Boy, Huu P. Nguyen, Peter Teismann, Thirumalaisamy Palanichamy Velavan, Philipp J. Kahle, Stephan von Hörsten, Markus Fendt, Rejko Krüger, Olaf Riess
Publikováno v: Neurobiology of Disease, Vol 44, Iss 2, Pp 192-204 (2011)
Mutations in the N-terminus of the gene encoding α-synuclein (α-syn) are linked to autosomal dominantly inherited Parkinson's disease (PD). The vast majority of PD patients develop neuropsychiatric symptoms preceding motor impairments. During this
Externí odkaz: https://doaj.org/article/45a07d5631fe4a16a4b98e9c9ce10074
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7
Selective protection of murine cerebral Gi/o-proteins from inactivation by parenterally injected pertussis toxin
Autor: Sandra Beer-Hammer, Bernd J. Pichler, Katja Pexa, Roland P. Piekorz, Bernd Nürnberg, Veronika Leiss, Carsten Calaminus, Vasudharani Devanathan, Christian Kesenheimer, Salvador Castaneda Vega, Marta Vuozzo, Andreas Schmid
Publikováno v: Journal of Molecular Medicine. 98:97-110
Pertussis toxin (PTX) is a potent virulence factor in patients suffering from whooping cough, but in its detoxified version, it is applied for vaccination. It is thought to contribute to the pathology of the disease including various CNS malfunctions
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c2d29b461ea1bd85aac49accd56c7d5
https://doi.org/10.1007/s00109-019-01854-1
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8
Retrobulbar Sinus Injection of Doxorubicin is More Efficient Than Lateral Tail Vein Injection at Inducing Experimental Nephrotic Syndrome in Mice: A Pilot Study
Autor: Antje Semrau, Carsten Calaminus, Sophie Daiminger, Ferruh Artunc, Franz Iglauer, Mai J Le, Almuth Falkenau, Bernhard N. Bohnert, Sandro Aidone, Thomas Dörffel
Publikováno v: Laboratory Animals
Doxorubicin-induced nephropathy in mice is a model for studying experimental nephrotic syndrome. It corresponds to puromycin aminonucleoside nephrosis in rats. In this model, susceptible 129 S1/SvImJ mice are administered a rapid intravenous injectio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27979aa30c1649dd4edb224c3cbef4fd
https://doi.org/10.1177/0023677218824382
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9
Non invasive in vivo monitoring of dimethyl fumarate treatment in EAE by assessing the glucose metabolism in secondary lymphoid organs
Autor: Bernd J. Pichler, Julia Holstein, Sabrina H. L. Hoffmann, Jürgen Brück, Manfred Kneilling, Johannes Schwenck, Carsten Calaminus, Kamran Ghoreschi, Amir S. Yazdi
Publikováno v: European journal of immunology 51(4), 1006-1009 (2020). doi:10.1002/eji.202048879
European journal of immunology eji.202048879 (2020). doi:10.1002/eji.202048879
Published by Wiley-VCH, Weinheim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f4a0caad68c5816f2c15c2663fc827
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10
An IgG‐based bispecific antibody for improved dual targeting in PSMA‐positive cancer
Autor: Jonas S. Heitmann, Joseph Kauer, Bernd J. Pichler, Hans-Georg Rammensee, Ilona Hagelstein, Marc A. Schneider, Melanie Märklin, Timo Manz, Carsten Calaminus, Arnulf Stenzl, Latifa Zekri, T. Todenhöfer, Stefanie Müller, Lars Zender, Sebastian Hörner, Lukas Osburg, Andreas Maurer, Gundram Jung, Fabian Vogt, Helmut R. Salih, Martin Pflügler, Bence Sipos, Christian la Fougère
Publikováno v: EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 13, Iss 2, Pp n/a-n/a (2021)
The prostate‐specific membrane antigen (PSMA) has been demonstrated in numerous studies to be expressed specifically on prostate carcinoma cells and on the neovasculature of several other cancer entities. However, the simultaneous expression of PSM
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075ec2f4e3d434bcd07694a31fb6ff23
http://europepmc.org/articles/PMC7863392
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