Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Carson Purnell"'
Autor:
Carson Purnell, Jessica Heebner, Michael T. Swulius, Ryan Hylton, Seth Kabonick, Michael Grillo, Sergei Grigoryev, Fred Heberle, M. Neal Waxham, Matthew T. Swulius
Deep learning excels at cryo-tomographic image restoration and segmentation tasks but is hindered by a lack of training data. Here we introduce cryo-TomoSim (CTS), a MATLAB-based software package that builds coarse-grained models of macromolecular co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d304312ee4533bd922e6ef32fdef32ad
https://doi.org/10.1101/2023.04.28.538636
https://doi.org/10.1101/2023.04.28.538636
Publikováno v:
Microscopy and Microanalysis. 28:1226-1228
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6fa2fe2974ed8c6228ada30684302d1
https://doi.org/10.1017/s1431927622005104
https://doi.org/10.1017/s1431927622005104
Autor:
Matthew T. Swulius, Michael A. Grillo, Mike Marsh, Ryan K. Hylton, Carson Purnell, Jessica E. Heebner
Publikováno v:
Journal of visualized experiments : JoVE. (189)
Cryo-electron tomography (cryo-ET) allows researchers to image cells in their native, hydrated state at the highest resolution currently possible. The technique has several limitations, however, that make analyzing the data it generates time-intensiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4772e6431420b111c762a2b9cc7b4525
https://pubmed.ncbi.nlm.nih.gov/36440884
https://pubmed.ncbi.nlm.nih.gov/36440884
Publikováno v:
SSRN Electronic Journal.
SUMMARYNucleosome chains fold and self-associate to form higher order structures whose internal organization is unknown. Here, cryo-electron tomography (cryo-ET) of native human chromatin reveals novel folding motifs such as 1) non-uniform nucleosome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e688859e686edd905bd1b03a830f7ae6
https://doi.org/10.2139/ssrn.4173452
https://doi.org/10.2139/ssrn.4173452
Publikováno v:
Biophysical Journal. 122:409a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b51100e5f8cc9c732773e0b7f2029523
https://doi.org/10.1016/j.bpj.2022.11.2221
https://doi.org/10.1016/j.bpj.2022.11.2221
Publikováno v:
Biophysical Journal. 122:140a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac94530e9ed02527c139fccccc975807
https://doi.org/10.1016/j.bpj.2022.11.916
https://doi.org/10.1016/j.bpj.2022.11.916
Autor:
Brandon Labarge, Max Hennessy, Lijun Zhang, David Goldrich, Scott Chartrand, Carson Purnell, Sage Wright, David Goldenberg, James R. Broach
Publikováno v:
Molecular cancer research : MCR. 20(9)
Human papillomavirus (HPV)-positive head and neck cancers, predominantly oropharyngeal squamous cell carcinoma (OPSCC), exhibit epidemiologic, clinical, and molecular characteristics distinct from those OPSCCs lacking HPV. We applied a combination of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81149e976eb35c4e014b67ec803cf1d0
https://pubmed.ncbi.nlm.nih.gov/35657601
https://pubmed.ncbi.nlm.nih.gov/35657601