Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Carson A. Wills"'
Autor:
Carson A. Wills, Xiaoming Liu, Longgui Chen, Yuanjun Zhao, Zhenqiu Liu, Vladimir S. Spiegelman, Jeffrey Sundstrom, Hong-Gang Wang
Publikováno v:
Genes and Diseases, Vol 11, Iss 4, Pp 101017- (2024)
Externí odkaz:
https://doaj.org/article/5f8937637a8f41b695486dea0b968e0c
Autor:
Mi Zhou, Sarah R. Weber, Yuanjun Zhao, Han Chen, Alistair J. Barber, Stephanie L. Grillo, Carson A. Wills, Hong Gang Wang, John D. Hulleman, Jeffrey M. Sundstrom
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
PurposeTo investigate the role of protein misfolding in retinal pigment epithelial (RPE) cell dysfunction, the effects of R345W-Fibulin-3 expression on RPE cell phenotype were studied.MethodsPrimary RPE cells were cultured to confluence on Transwells
Externí odkaz:
https://doaj.org/article/23db40c4680440e7ab5dafdc5ecb170f
Autor:
Yoshinori Takahashi, Haiyan He, Zhenyuan Tang, Tatsuya Hattori, Ying Liu, Megan M. Young, Jacob M. Serfass, Longgui Chen, Melat Gebru, Chong Chen, Carson A. Wills, Jennifer M. Atkinson, Han Chen, Thomas Abraham, Hong-Gang Wang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
During autophagy, phagophores elongate to form double-membrane vesicles but the mechanism behind their closure is unknown. Here, the authors develop an autophagy assay and find a role for the endosomal sorting complexes required for transport compone
Externí odkaz:
https://doaj.org/article/dc0bd3a5e9b64caca02caa285ccc24af
Autor:
Hong-Gang Wang, Jeffrey Sundstrom, Christopher M. Dower, Yuanjun Zhao, Longgui Chen, Xiaoming Liu, Carson A. Wills
Chemotherapy upregulates small extracellular vesicle-associated PTX3 protein expression, which has no effect on cell migration and invasion in vitro or primary tumor growth in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048e526e3ae25c92c85aa8639920fc4d
https://doi.org/10.1158/0008-5472.22426822
https://doi.org/10.1158/0008-5472.22426822
Autor:
Hong-Gang Wang, Jeffrey Sundstrom, Christopher M. Dower, Yuanjun Zhao, Longgui Chen, Xiaoming Liu, Carson A. Wills
Although neoadjuvant chemotherapy is a standard component of breast cancer treatment, recent evidence suggests that chemotherapeutic drugs can promote metastasis through poorly defined mechanisms. Here we utilize xenograft mouse models of triple-nega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c4c984894a5fe98405ea09a63f1884
https://doi.org/10.1158/0008-5472.c.6512464.v1
https://doi.org/10.1158/0008-5472.c.6512464.v1
Autor:
Hong-Gang Wang, Jeffrey Sundstrom, Christopher M. Dower, Yuanjun Zhao, Longgui Chen, Xiaoming Liu, Carson A. Wills
Supplementary Methods and Materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75639a9e34227d5eff9e86764627f6e1
https://doi.org/10.1158/0008-5472.22426816
https://doi.org/10.1158/0008-5472.22426816
Autor:
Carson A. Wills, Christopher M. Dower, Xiaoming Liu, Yuanjun Zhao, Jeffrey M. Sundstrom, Hong Gang Wang, Longgui Chen
Publikováno v:
Cancer Res
Although neoadjuvant chemotherapy is a standard component of breast cancer treatment, recent evidence suggests that chemotherapeutic drugs can promote metastasis through poorly defined mechanisms. Here we utilize xenograft mouse models of triple-nega
Autor:
Xiaoming Liu, Carson A Wills, Longgui Chen, Jiawen Zhang, Yuanjun Zhao, Mi Zhou, Jeffrey M Sundstrom, Todd Schell, Vladimir S Spiegelman, Megan M Young, Hong-Gang Wang
Publikováno v:
Journal for immunotherapy of cancer. 10(4)
BackgroundAnti-GD2 monoclonal antibody immunotherapy has significantly improved the overall survival rate for high-risk neuroblastoma patients. However, 40% of patients fail to respond or develop resistance to treatment, and the molecular mechanisms
Autor:
Yoshinori Takahashi, Tatsuya Hattori, Longgui Chen, Carson A. Wills, Hong Gang Wang, Zhenyuan Tang, Xinwen Liang
Publikováno v:
Cell Death Differ
Autophagosomal membranes can serve as activation platforms for intracellular death-inducing signaling complexes (iDISCs) to initiate Caspase-8-dependent apoptosis. In this study, we explore the impact of ESCRT-III-dependent phagophore closure on iDIS
Publikováno v:
In Vivo
Background/Aim: Neuroblastoma is clinically and molecularly heterogeneous, with poor outcomes despite multimodal treatment strategies. The primary tumor site is an independent predictor of survival; adrenal tumors have the worst outcomes, while poste