Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Carrier Proteins metabolism"'
Publikováno v:
Critical Reviews in Biochemistry and Molecular Biology. 57(4):377-398
The Notch signaling pathway is a direct cell-cell communication system involved in a wide variety of biological processes, and its disruption is observed in several pathologies. The pathway is comprised of a ligand-expressing (sender) cell and a rece
Publikováno v:
Critical reviews in biochemistry and molecular biology. 57(4)
The Notch signaling pathway is a direct cell-cell communication system involved in a wide variety of biological processes, and its disruption is observed in several pathologies. The pathway is comprised of a ligand-expressing (sender) cell and a rece
Publikováno v:
Thingholm, T E, Rönnstrand, L & Rosenberg, P A 2020, ' Why and how to investigate the role of protein phosphorylation in ZIP and ZnT zinc transporter activity and regulation ', Cellular and Molecular Life Sciences, vol. 77, no. 16, pp. 3085-3102 . https://doi.org/10.1007/s00018-020-03473-3
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences
Zinc is required for the regulation of proliferation, metabolism, and cell signaling. It is an intracellular second messenger, and the cellular level of ionic, mobile zinc is strictly controlled by zinc transporters. In mammals, zinc homeostasis is p
Autor:
Jasmin Bartl, Marco Zanini, Flavia Bernardi, Antoine Forget, Lena Blümel, Julie Talbot, Daniel Picard, Nan Qin, Gabriele Cancila, Qingsong Gao, Soumav Nath, Idriss Mahoungou Koumba, Marietta Wolter, François Kuonen, Maike Langini, Thomas Beez, Christopher Munoz, David Pauck, Viktoria Marquardt, Hua Yu, Judith Souphron, Mascha Korsch, Christina Mölders, Daniel Berger, Sarah Göbbels, Frauke-Dorothee Meyer, Björn Scheffler, Barak Rotblat, Sven Diederichs, Vijay Ramaswamy, Hiromishi Suzuki, Anthony Oro, Kai Stühler, Anja Stefanski, Ute Fischer, Gabriel Leprivier, Dieter Willbold, Gerhard Steger, Alexander Buell, Marcel Kool, Peter Lichter, Stefan M. Pfister, Paul A. Northcott, Michael D. Taylor, Arndt Borkhardt, Guido Reifenberger, Olivier Ayrault, Marc Remke
Publikováno v:
Nature Communications 13(1), 4061 (2022). doi:10.1038/s41467-022-31574-z
Nature communications, vol. 13, no. 1, pp. 4061
Bartl, J, Zanini, M, Bernardi, F, Forget, A, Blümel, L, Talbot, J, Picard, D, Qin, N, Cancila, G, Gao, Q, Nath, S, Koumba, I M, Wolter, M, Kuonen, F, Langini, M, Beez, T, Munoz, C, Pauck, D, Marquardt, V, Yu, H, Souphron, J, Korsch, M, Mölders, C, Berger, D, Göbbels, S, Meyer, F-D, Scheffler, B, Rotblat, B, Diederichs, S, Ramaswamy, V, Suzuki, H, Oro, A, Stühler, K, Stefanski, A, Fischer, U, Leprivier, G, Willbold, D, Steger, G, Buell, A, Kool, M, Lichter, P, Pfister, S M, Northcott, P A, Taylor, M D, Borkhardt, A, Reifenberger, G, Ayrault, O & Remke, M 2022, ' The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors ', Nature Communications, vol. 13, 4061 . https://doi.org/10.1038/s41467-022-31574-z
Nature Communications
Nature Communications, 2022, 13 (1), pp.4061. ⟨10.1038/s41467-022-31574-z⟩
Nature communications, vol. 13, no. 1, pp. 4061
Bartl, J, Zanini, M, Bernardi, F, Forget, A, Blümel, L, Talbot, J, Picard, D, Qin, N, Cancila, G, Gao, Q, Nath, S, Koumba, I M, Wolter, M, Kuonen, F, Langini, M, Beez, T, Munoz, C, Pauck, D, Marquardt, V, Yu, H, Souphron, J, Korsch, M, Mölders, C, Berger, D, Göbbels, S, Meyer, F-D, Scheffler, B, Rotblat, B, Diederichs, S, Ramaswamy, V, Suzuki, H, Oro, A, Stühler, K, Stefanski, A, Fischer, U, Leprivier, G, Willbold, D, Steger, G, Buell, A, Kool, M, Lichter, P, Pfister, S M, Northcott, P A, Taylor, M D, Borkhardt, A, Reifenberger, G, Ayrault, O & Remke, M 2022, ' The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors ', Nature Communications, vol. 13, 4061 . https://doi.org/10.1038/s41467-022-31574-z
Nature Communications
Nature Communications, 2022, 13 (1), pp.4061. ⟨10.1038/s41467-022-31574-z⟩
Most lncRNAs display species-specific expression patterns suggesting that animal models of cancer may only incompletely recapitulate the regulatory crosstalk between lncRNAs and oncogenic pathways in humans. Among these pathways, Sonic Hedgehog (SHH)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ec632d06d6284086a564a448ef81a7
https://hdl.handle.net/2128/31691
https://hdl.handle.net/2128/31691
Autor:
Ian Collinson, Xia Liu, Mark S. Dillingham, Gonçalo C. Pereira, Holly C Ford, William J. Allen
Publikováno v:
Ford, H C, Allen, W J, Pereira, G C, Liu, X, Dillingham, M S & Collinson, I 2022, ' Towards a molecular mechanism underlying mitochondrial protein import through the TOM and TIM23 complexes ', eLife, vol. 11, e75426 . https://doi.org/10.7554/eLife.75426
Nearly all mitochondrial proteins need to be targeted for import from the cytosol. For the majority, the first port of call is the translocase of the outer membrane (TOM complex), followed by a procession of alternative molecular machines, conducting
Autor:
Bombaci, Giuseppe, Sarangdhar, Mayuresh Anant, Andina, Nicola, Tardivel, Aubry, Yu, Eric Chi-Wang, Mackie, Gillian M, Pugh, Matthew, Ozan, Vedat Burak, Banz, Yara, Spinetti, Thibaud, Hirzel, Cedric, Youd, Esther, Schefold, Joerg C, Taylor, Graham, Gazdhar, Amiq, Bonadies, Nicolas, Angelillo-Scherrer, Anne, Schneider, Pascal, Maslowski, Kendle M, Allam, Ramanjaneyulu
Publikováno v:
Life science alliance, vol. 5, no. 6, pp. e202101226
Bombaci, Giuseppe; Sarangdhar, Mayuresh Anant; Andina, Nicola; Tardivel, Aubry; Yu, Eric Chi-Wang; Mackie, Gillian M; Pugh, Matthew; Ozan, Vedat Burak; Banz, Yara; Spinetti, Thibaud; Hirzel, Cédric; Youd, Esther; Schefold, Joerg C; Taylor, Graham; Gazdhar, Amiq; Bonadies, Nicolas; Angelillo-Scherrer, Anne; Schneider, Pascal; Maslowski, Kendle M and Allam, Ramanjaneyulu (2022). LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity. Life science alliance, 5(6) EMBO Press 10.26508/lsa.202101226
Bombaci, Giuseppe; Sarangdhar, Mayuresh Anant; Andina, Nicola; Tardivel, Aubry; Yu, Eric Chi-Wang; Mackie, Gillian M; Pugh, Matthew; Ozan, Vedat Burak; Banz, Yara; Spinetti, Thibaud; Hirzel, Cédric; Youd, Esther; Schefold, Joerg C; Taylor, Graham; Gazdhar, Amiq; Bonadies, Nicolas; Angelillo-Scherrer, Anne; Schneider, Pascal; Maslowski, Kendle M and Allam, Ramanjaneyulu (2022). LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity. Life science alliance, 5(6) EMBO Press 10.26508/lsa.202101226
Inflammasomes are cytosolic innate immune sensors of pathogen infection and cellular damage that induce caspase-1-mediated inflammation upon activation. Although inflammation is protective, uncontrolled excessive inflammation can cause inflammatory d
Publikováno v:
Methods in Molecular Biology ISBN: 9781071608135
Lipid Rafts: Methods and Protocols, 2187, 327-335
Lipid Rafts: Methods and Protocols, 2187, 327-335
Fluorescence microscopy is a powerful and widely used tool in molecular biology. Over the years, the discovery and development of lipid-binding fluorescent probes has established new research possibilities to investigate lipid composition and dynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c72686d69e90f8496e6010e983b1c29
https://doi.org/10.1007/978-1-0716-0814-2_19
https://doi.org/10.1007/978-1-0716-0814-2_19
Autor:
Feichtinger R. G., Olahova M., Kishita Y., Garone C., Kremer L. S., Yagi M., Uchiumi T., Jourdain A. A., Thompson K., D'Souza A. R., Kopajtich R., Alston C. L., Koch J., Sperl W., Mastantuono E., Strom T. M., Wortmann S. B., Meitinger T., Pierre G., Chinnery P. F., Chrzanowska-Lightowlers Z. M., Lightowlers R. N., DiMauro S., Calvo S. E., Mootha V. K., Moggio M., Sciacco M., Comi G. P., Ronchi D., Murayama K., Ohtake A., Rebelo-Guiomar P., Kohda M., Kang D., Mayr J. A., Taylor R. W., Okazaki Y., Minczuk M., Prokisch H.
Publikováno v:
American Journal of Human Genetics
American journal of human genetics, vol. 101, no. 4, pp. 525-538
American journal of human genetics, vol. 101, no. 4, pp. 525-538
Complement component 1 Q subcomponent-binding protein (C1QBP; also known as p32) is a multi-compartmental protein whose precise function remains unknown. It is an evolutionary conserved multifunctional protein localized primarily in the mitochondrial
Autor:
Darius Vasco Köster, Cédric M. Blouin, Paolo Pierobon, Vassili Soumelis, Satish Kailasam Mani, Christine Viaris de Lesegno, Ludger Johannes, Alexandre Grassart, Valérie Chambon, Wei-Wei Shen, Stéphanie Torrino, Catherine Coirault, Cesar Augusto Valades-Cruz, Stéphane Vassilopoulos, Pierre Bost, Christophe Lamaze
Publikováno v:
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2018, 217 (12), pp.4092-4105. ⟨10.1083/jcb.201801122⟩
The Journal of Cell Biology
Journal of Cell Biology, 2018, 217 (12), pp.4092-4105. ⟨10.1083/jcb.201801122⟩
Journal of Cell Biology, Rockefeller University Press, 2018, 217 (12), pp.4092-4105. ⟨10.1083/jcb.201801122⟩
The Journal of Cell Biology
Journal of Cell Biology, 2018, 217 (12), pp.4092-4105. ⟨10.1083/jcb.201801122⟩
Caveolae are dynamic mechanosensors. Torrino et al. show that EHD2 plays a crucial role in the adaptation to mechanical perturbations by maintaining the caveolae reservoir at the plasma membrane after changes in membrane tension and connecting caveol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7042e1f7a0a83c4b843ac2dcf8af90
https://www.hal.inserm.fr/inserm-02426440
https://www.hal.inserm.fr/inserm-02426440
Autor:
Towler, MC, Gleeson, PA, Hoshino, S, Rahkila, P, Ohkoshi, N, Ordahl, CP, Parton, RG, Brodsky, FM
Publikováno v:
Towler, MC; Gleeson, PA; Hoshino, S; Rahkila, P; Ohkoshi, N; Ordahl, CP; et al.(2017). Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration. Molecular Biology of the Cell. doi: 10.1091/mbc.E04-03-0249. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/0k721808
The muscle isoform of clathrin heavy chain, CHC22, has 85% sequence identity to the ubiquitously expressed CHC17, yet its expression pattern and function appear to be distinct from those of well-characterized clathrin-coated vesicles. In mature muscl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::675ee23bce0e89da23df6d18b79500bd
http://www.escholarship.org/uc/item/0k721808
http://www.escholarship.org/uc/item/0k721808