Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Carrie S. Viars"'
Autor:
Cameron N. Johnstone, William H. Biggs, Fiona J. Clay, Sara J. White, Matthias Ernst, Carrie S. Viars, Niall C. Tebbutt, Joan K. Heath, Suzanne Czekay, Karen C. Arden
Publikováno v:
Journal of Biological Chemistry. 277:34531-34539
The A33 antigen is a transmembrane protein expressed almost exclusively by intestinal epithelial cells. The level of its expression is robust and uniform throughout the rostrocaudal axis of the human and mouse intestines. In the colon, strong express
Autor:
Ali O. Gure, Elisabeth Stockert, Carrie S. Viars, Yao-Tseng Chen, Matthew J. Scanlan, Lloyd J. Old, Karen C. Arden, Antonia D. Boyer
Publikováno v:
International Journal of Cancer. 85:726-732
Assays relying on humoral or T-cell-based recognition of tumor antigens to identify potential targets for immunotherapy have led to the discovery of a significant number of immunogenic gene products, including cancer-testis (CT) antigens predominantl
Autor:
Carrie S. Viars, M. Böhm, Ilse Wieland, Ludger Klein-Hitpass, D Michels, Ulrich H. Weidle, Karen C. Arden
Publikováno v:
Oncogene. 18:4530-4537
In the development and progression of sporadic tumors multiple tumor suppressor genes are inactivated that may be distinct from predisposing cancer genes. Previously, a tumor suppressor locus on human chromosome 13q14 that is distinct from the retino
Autor:
Antonia D. Boyer, Carrie S. Viars, Huan You Wang, John R. Bermingham, Wen Lin, Xiang-Dong Fu, Karen C. Arden
Publikováno v:
Genomics. 57:310-315
The serine- and arginine-rich (SR) splicing factors play an important role in both constitutive and alternative pre-mRNA splicing, and the functions of these splicing factors are regulated by phosphorylation. We have previously characterized SRPK1 (S
Autor:
Carrie S. Viars, Douglas M. Daub, Michele Albertoni, Cathy Powell, Erwin G. Van Meir, Karen C. Arden
Publikováno v:
Oncogene. 16:321-326
Little is known about the relationship between genetic recombination mechanisms and loss of tumour suppressor genes in solid tumours. Here, we demonstrate deletion and truncation of both p53 alleles in a primary human glioblastoma and a derived cell
Publikováno v:
Cytogenetic and Genome Research. 79:237-240
CTAG was initially cloned from an esophageal squamous cell carcinoma cDNA expression library by immunoscreening with autologous patient’s serum. CTAG mRNA is expressed in a proportion of human cancers in a lineage-nonspecific fashion, whereas its e
Autor:
Carrie S. Viars, X-D. Fu, Michael G. Rosenfeld, John R. Bermingham, Anna K. Naumova, Carmen Sapienza, Karen C. Arden, James L. Manley, Jhumku Khotz
Publikováno v:
Genomics. 29:70-79
The mammalian SR-type splicing factors ASF/SF2 and SC-35 play crucial roles in pre-mRNA splicing and have been shown to shift splice site choice in vitro. We have mapped the ASF/SF2 gene in mice and humans and the SC-35 gene in mice. Somatic cell hyb
Publikováno v:
Genomics. 26:385-389
Cardiac myocytes synthesize and secrete a family of peptide hormones with potent natriuretic, diuretic, and vasodilatory properties. These peptides are derived from precursor molecules that are encoded by two different genes, the atrial natriuretic p
Publikováno v:
BMC Genomics
BMC Genomics, Vol 4, Iss 1, p 39 (2003)
BMC Genomics, Vol 4, Iss 1, p 39 (2003)
Background In order to facilitate the identification of genes involved in the metastatic phenotype we have previously developed a pair of cell lines from the human breast carcinoma cell line MDA-MB-435, which have diametrically opposite metastatic po
Publikováno v:
Genes, chromosomescancer. 34(1)
The tumor cell line HT-29 was derived from a primary adenocarcinoma of the rectosigmoid colon. HT-29 is hypertriploid (3n+) and has accumulated numerous chromosomal structural aberrations. To identify material involved in chromosome rearrangements, w