Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Carrie R. Cowan"'
Autor:
Martin Mikl, Carrie R. Cowan
Publikováno v:
Cell Reports, Vol 8, Iss 5, Pp 1380-1390 (2014)
Cell polarity in one-cell C. elegans embryos guides asymmetric cell division and cell-fate specification. Shortly after fertilization, embryos establish two antagonistic cortical domains of PAR proteins. Here, we find that the conserved polarity fact
Externí odkaz:
https://doaj.org/article/a29d60ae39e14cc7898e84f4b8035796
Publikováno v:
Current Biology
Summary Centrosome function in cell division requires their duplication, once, and only once, per cell cycle. Underlying centrosome duplication are alternating cycles of centriole assembly and separation [1]. Work in vertebrates has implicated the cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::12cbeb4e6203d418acbca0265fb4e5b2
Autor:
Dominika Bienkowska, Carrie R. Cowan
Publikováno v:
Current Biology. 22(7):583-589
SummaryThe stereotyped asymmetry of one-cell C. elegans embryos has proven to be an important model for identifying molecular determinants of cell polarity [1]. How polarity is initiated is less well understood. Polarity establishment depends on cent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b43b550a60fde7accc008c0ba37981
Publikováno v:
Development. 137:1743-1753
In asymmetrically dividing cells, a failure to coordinate cell polarity with the site of cell division can lead to cell fate transformations and tumorigenesis. Cell polarity in C. elegans embryos is defined by PAR proteins, which occupy reciprocal ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::117e135d7cc2511a12789d58154afc6e
https://doi.org/10.1242/dev.040436
https://doi.org/10.1242/dev.040436
Autor:
David B. Kaback, Hailin Wang, Eric J. White, Carrie R. Cowan, W. Zacheus Cande, Harry Scherthan, Caroline Adelfalk
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America : PNAS
In many organisms, a synaptonemal complex (SC) intimately connects each pair of homologous chromosomes during much of the first meiotic prophase and is thought to play a role in regulating recombination. In the yeast Saccharomyces cerevisiae , the ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e193f0bf97b5469ba9b4e94560a760bb
https://doi.org/10.1073/pnas.0704860104
https://doi.org/10.1073/pnas.0704860104
Publikováno v:
Current Biology
SummaryAt anaphase, the mitotic spindle positions the cytokinesis furrow [1]. Two populations of spindle microtubules are implicated in cytokinesis: radial microtubule arrays called asters and bundled nonkinetochore microtubules called the spindle mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ac98d5683414695598a468457eb0c0
https://doi.org/10.1016/j.cub.2006.11.070
https://doi.org/10.1016/j.cub.2006.11.070
Autor:
Martin Mikl, Carrie R. Cowan
Publikováno v:
Cell Polarity 2 ISBN: 9783319144658
Cell polarity in one-cell C. elegans embryos guides an asymmetric cell division that starts the resulting cells along different developmental paths. Cell polarization starts in response to a signal from the centrosomes, triggering a cell-wide reorgan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f239b85b042c09b56d92d923146bca6
https://doi.org/10.1007/978-3-319-14466-5_1
https://doi.org/10.1007/978-3-319-14466-5_1
Autor:
Anthony A. Hyman, Carrie R. Cowan
Publikováno v:
Nature Cell Biology. 8:1441-1447
Establishment of polarity in C. elegans embryos is dependent on the centrosome1. The sperm contributes a pair of centrioles to the egg and these centrioles remain incapable of polarizing the cortex while the egg completes meiosis. Coincident with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e3aebf884b362979b697c15d8e8c57
https://doi.org/10.1038/ncb1511
https://doi.org/10.1038/ncb1511
Autor:
Carrie R. Cowan, Anthony A. Hyman
Publikováno v:
Annual Review of Cell and Developmental Biology. 20:427-453
▪ Abstract The one-cell Caenorhabditis elegans embryo divides asymmetrically into a larger and smaller blastomere, each with a different fate. How does such asymmetry arise? The sperm-supplied centrosome establishes an axis of polarity in the embry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19254bf38fd49c90304c4333bc2238d
https://doi.org/10.1146/annurev.cellbio.19.111301.113823
https://doi.org/10.1146/annurev.cellbio.19.111301.113823
Autor:
Anthony A. Hyman, Carrie R. Cowan
Publikováno v:
Nature. 431:92-96
Polarity establishment requires a symmetry-breaking event, resulting in an axis along which determinants are segregated. In Caenorhabditis elegans, oocytes are apolar and are triggered to polarize rapidly along one axis after fertilization. The estab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b66b9006e0645f63cd2bd04d3db3964
https://doi.org/10.1038/nature02825
https://doi.org/10.1038/nature02825