Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Carrie Newbold"'
Autor:
Alexander R. Harris, Carrie Newbold, Dimitra Stathopoulos, Paul Carter, Robert Cowan, Gordon G. Wallace
Publikováno v:
Micromachines, Vol 13, Iss 1, p 103 (2022)
The electrochemical performance of platinum electrodes was assessed in vitro and in vivo to determine the impact of electrode implantation and the relevance of in vitro testing in predicting in vivo behaviour. A significant change in electrochemical
Externí odkaz:
https://doaj.org/article/8bf872afe02b452486bb8d7f961921c1
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
The safe charge injection capacity and charge density of neural stimulating electrodes is based on empirical evidence obtained from stimulating feline cortices. Stimulation induced tissue damage may be caused by electrochemical or biological mechanis
Externí odkaz:
https://doaj.org/article/ddde2b596b2543488c433cafffb2fcde
Autor:
Jason Leavens, Robert Cowan, Carrie Newbold, Shahram Manouchehri, Frank Risi, Karina Needham, Irfan Durmo, Dimitra Stathopoulos
Publikováno v:
Cochlear Implants International. 21:98-109
Postoperative inflammation and the formation of fibrotic tissue around the intracochlear electrode array are often held responsible for negative outcomes in cochlear implant recipients. Here we test the effectiveness of intracochlear delivery of dexa
Publikováno v:
Journal of The Electrochemical Society. 166:G131-G140
The charge transfer mechanism at the electrode-solution interface was assessed by Fourier transform AC voltammetry (FTACV). The faradaic reactions that occur within the safe potential window on platinum had slow electron transfer kinetics. The charge
Autor:
Robert Cowan, Carrie Newbold, Scott W. Chambers, Frank Risi, Karina Needham, Christopher Miller, Dimitra Stathopoulos, Godofredo Timbol, Ya Lang Enke
Publikováno v:
Cochlear Implants International. 20:1-11
OBJECTIVE: To compare the benefits of a dexamethasone-eluting array for hearing preservation and cochlear histopathology in low trauma (soft-surgery) and high trauma models of cochlear implant surgery. METHODS: Adult guinea pigs were implanted with a
Publikováno v:
Journal of The Electrochemical Society. 165:G3033-G3041
The chronoamperometric response of platinum under biologically relevant conditions was investigated to understand how charge transfer across the electrode-tissue interface occurs during potential pulsing. Platinum behaves as a non-ideal electrode, pa
Publikováno v:
Journal of Manufacturing Processes. 22:21-25
Traditionally, fabrication processes to produce microelectrode arrays for neural stimulating electrodes have employed photolithography and a photoresist layer to produce a pattern on a substrate which subsequently has a metal layer deposited. The dep
Autor:
June Choi, Matthew R. Payne, Carrie Newbold, Hayden Eastwood, Stephen O'Leary, Luke Campbell, Christo Bester
Publikováno v:
Otologyneurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 38(10)
OBJECTIVES/HYPOTHESIS: Cochlear implant surgery now aims to preserve residual low frequency hearing. The current research explores whether fluctuations in the electrical impedance of cochlear implant electrodes may act as a biomarker for pathological
Autor:
Hayden Eastwood, Aaron Collins, Stephen O'Leary, Amy Hampson, Scott Chambers, Jonathon Lo, Carrie Newbold, Christofer Bester
Publikováno v:
Hearing research. 358
To preserve residual hearing, techniques for monitoring and reducing the effects of trauma during cochlear implant surgery are being developed. This study examines the relationships between intraoperative recordings (electrode insertion force and ele
Autor:
Rachael T. Richardson, Silvana Mergen, Peter M. Seligman, Robert K. Shepherd, Rodney E. Millard, Robert Cowan, Carrie Newbold
Publikováno v:
Cochlear Implants International. 15:191-199
OBJECTIVES: Electrode impedance increases following implantation and undergoes transitory reduction with onset of electrical stimulation. The studies in this paper measured the changes in access resistance and polarization impedance in vivo before an