Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Carrie L. Wade"'
Autor:
Carrie L Wade, Perry Krumenacher, Kelley F Kitto, Cristina D Peterson, George L Wilcox, Carolyn A Fairbanks
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79239 (2013)
The development of opioid addiction in subjects with established chronic pain is an area that is poorly understood. It is critically important to clearly understand the neurobiology associated with propensity toward conversion to addiction under cond
Externí odkaz:
https://doaj.org/article/06f4520ed5b64356a5063109df35945d
Autor:
Emmanuel Breysse, Carrie L. Wade, Marsida Kallupi, Paul Schweitzer, Olivier George, Daniel O Hernandez, George F. Koob, Elena Crawford, Giordano de Guglielmo, Christelle Baunez
Publikováno v:
Neuropsychopharmacology. 42:1850-1859
Opioid addiction, including addiction to heroin, has markedly increased in the past decade. The cost and pervasiveness of heroin addiction, including resistance to recovery from addiction, provide a compelling basis for developing novel therapeutic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402c0abc131f986eec778e07de501162
https://doi.org/10.1038/npp.2016.270
https://doi.org/10.1038/npp.2016.270
Autor:
Joel E. Schlosburg, George F. Koob, Daniel O Hernandez, Leandro F. Vendruscolo, Carrie L. Wade
Publikováno v:
Neuropsychopharmacology. 40:421-428
The abuse of prescription opioids that are used for the treatment of chronic pain is a major public health concern, costing ∼$53.4 billion annually in lost wages, health-care costs, and criminal costs. Although opioids remain a first-line therapy f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea127dee982873d7b1de91fb625b1460
https://doi.org/10.1038/npp.2014.188
https://doi.org/10.1038/npp.2014.188
Autor:
Kim D. Janda, G. Neil Stowe, Leandro F. Vendruscolo, Joel E. Schlosburg, George F. Koob, Scott Edwards, Jonathan W. Lockner, Ashlee A. K. Nunes, Paul T. Bremer, Carrie L. Wade
Publikováno v:
Proceedings of the National Academy of Sciences. 110:9036-9041
Heroin addiction, a chronic relapsing disorder characterized by excessive drug taking and seeking, requires constant psychotherapeutic and pharmacotherapeutic interventions to minimize the potential for further abuse. Vaccine strategies against many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c70b179bb23adcddf8b59669c48174
https://doi.org/10.1073/pnas.1219159110
https://doi.org/10.1073/pnas.1219159110
Autor:
Carrie L. Wade, Kelley F. Kitto, George L. Wilcox, Lori L. Eskridge, H. Oanh X. Nguyen, Laura S. Stone, Carolyn A. Fairbanks
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 331:539-546
Systemically or centrally administered agmatine (decarboxylated arginine) prevents, moderates, or reverses opioid-induced tolerance and self-administration, inflammatory and neuropathic pain, and sequelae associated with ischemia and spinal cord inju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1828309707e6b799fb563bed6410bd66
https://doi.org/10.1124/jpet.109.155424
https://doi.org/10.1124/jpet.109.155424
Autor:
Carrie L. Wade, James J. Lynch, Hongyu Xu, Kennan C. Marsh, Chengmin Zhong, Kathleen H. Mortell, Chih Hung Lee, Michael F. Jarvis, Chang Z. Zhu, William H. Bunnelle, David J. Anderson, Murali Gopalakrishnan, Prisca Honore
Publikováno v:
Pain. 125:136-142
Gabapentin and pregabalin have been demonstrated, both in animal pain models and clinically, to be effective analgesics particularly for the treatment of neuropathic pain. The precise mechanism of action for these two drugs is unknown, but they are g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba60e77cd12767e06e4ff8be1eb38c4
https://doi.org/10.1016/j.pain.2006.05.012
https://doi.org/10.1016/j.pain.2006.05.012
ABT-594 (a nicotinic acetylcholine agonist): anti-allodynia in a rat chemotherapy-induced pain model
Publikováno v:
European Journal of Pharmacology. 509:43-48
ABT-594 ((R)-5-(2-azetidinylmethoxy)-2-chloropyridine) represents a novel class of broad-spectrum analgesics whose primary mechanism of action is activation of the neuronal nicotinic acetylcholine receptors. The present study characterized the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afdc648835ae404d5ac53f1fc2d6b32
https://doi.org/10.1016/j.ejphar.2004.12.034
https://doi.org/10.1016/j.ejphar.2004.12.034
Autor:
Prisca Honore, Joseph P. Mikusa, Donna M. Gauvin, Michael W. Decker, Chang Z. Zhu, Sonya G. Wilson, Carol T. Wismer, Carrie L. Wade, James J. Lynch
Publikováno v:
European Journal of Pharmacology. 506:107-118
Preclinical data, performed in a limited number of pain models, suggest that functional blockade of metabotropic glutamate (mGlu) receptors may be beneficial for pain management. In the present study, effects of 2-methyl-6-(phenylethynyl)-pyridine (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b5b7e524f665038ffd57396dfa2620
https://doi.org/10.1016/j.ejphar.2004.11.005
https://doi.org/10.1016/j.ejphar.2004.11.005
Autor:
Carrie L, Wade, Carolyn A, Fairbanks
Publikováno v:
Current topics in behavioral neurosciences. 20
Systemically and centrally delivered opioids have been comprehensively studied for their effects both in analgesic and addiction models for many decades, primarily in subjects with presumptive normal sensory thresholds. The introduction of disease-ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::70b9e1dd67594cb824cc1f716bb46871
https://pubmed.ncbi.nlm.nih.gov/25205326
https://pubmed.ncbi.nlm.nih.gov/25205326
Autor:
Carrie L. Wade, Carolyn A. Fairbanks
Publikováno v:
Neurobiological Studies of Addiction in Chronic Pain States ISBN: 9781493918553
It has been long recognized that chronic pain is a significant public health concern. After many decades of research and development investment for alternatives, the most effective pharmacological tools for managing diverse chronic pains remain the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b934f0b29ab9f310c538dc01d2ce880c
https://doi.org/10.1007/978-1-4939-1856-0_1
https://doi.org/10.1007/978-1-4939-1856-0_1
