Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Carrie L. Fuertes"'
Autor:
Kajsa E. Affolter, Sabine Hellwig, David A. Nix, Mary P. Bronner, Alun Thomas, Carrie L. Fuertes, Cindy L. Hamil, Ignacio Garrido-Laguna, Courtney L. Scaife, Sean J. Mulvihill, Hunter R. Underhill
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 859-869 (2021)
The confounding effects of next-generation sequencing (NGS) noise on detection of low frequency circulating tumor DNA (ctDNA) without a priori knowledge of solid tumor mutations has limited the applications of circulating cell-free DNA (ccfDNA) in cl
Externí odkaz:
https://doaj.org/article/358af70ad57a48859ddd7ab16dc40fd3
Autor:
Sabine Hellwig, David A Nix, Keith M Gligorich, John M O'Shea, Alun Thomas, Carrie L Fuertes, Preetida J Bhetariya, Gabor T Marth, Mary P Bronner, Hunter R Underhill
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0197333 (2018)
Circulating tumor-derived cell-free DNA (ctDNA) enables non-invasive diagnosis, monitoring, and treatment susceptibility testing in human cancers. However, accurate detection of variant alleles, particularly during untargeted searches, remains a prin
Externí odkaz:
https://doaj.org/article/757b4bcee6f344cda97d7d9a78e756a2
Autor:
Mary P. Bronner, David A. Nix, Kajsa E. Affolter, Ignacio Garrido-Laguna, Courtney L. Scaife, Sean J. Mulvihill, Carrie L. Fuertes, Hunter R Underhill, Sabine Hellwig, Alun Thomas, Cindy Hamil
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 859-869 (2021)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 859-869 (2021)
The confounding effects of next-generation sequencing (NGS) noise on detection of low frequency circulating tumor DNA (ctDNA) without a priori knowledge of solid tumor mutations has limited the applications of circulating cell-free DNA (ccfDNA) in cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4443f9b95c739f99f1a28eeafcc93cc
http://europepmc.org/articles/PMC8322473
http://europepmc.org/articles/PMC8322473
Autor:
Mary P. Bronner, Alun Thomas, Carrie L. Fuertes, Ignacio Garrido-Laguna, Hunter R. Underhill, Cindy Hamil, Christopher J. Conley, Sabine Hellwig, Preetida J. Bhetariya, Gabor T. Marth, David A. Nix
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229063 (2020)
PLoS ONE
PLoS ONE
Challenges with distinguishing circulating tumor DNA (ctDNA) from next-generation sequencing (NGS) artifacts limits variant searches to established solid tumor mutations. Here we show early and random PCR errors are a principal source of NGS noise th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06f0a5705817fdbf7769605c17169f6
https://doaj.org/article/5718b9aa273541e6820abd8340717128
https://doaj.org/article/5718b9aa273541e6820abd8340717128
Autor:
David A. Nix, Sabine Hellwig, Mary P. Bronner, Gabor T. Marth, Carrie L. Fuertes, Preetida J. Bhetariya, Howard Colman, Hunter R. Underhill, Randy L. Jensen
Detection of tumor-derived circulating cell-free DNA (ccfDNA) in plasma from glioblastoma patients remains elusive. The vast intra-tumor genetic heterogeneity of glioblastoma has limited targeted searches using a priori molecular profiling from a foc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4f7e3578bdf8fb8ed35951dccc0fc8
https://europepmc.org/articles/PMC6217174/
https://europepmc.org/articles/PMC6217174/
Autor:
Randy L. Jensen, Mary P. Bronner, Christian Davidson, Hunter R. Underhill, Howard Colman, Sabine Hellwig, Carrie L. Fuertes, David A. Nix
Publikováno v:
Neuro Oncol
Glioblastoma’s mutational landscape varies widely in the same tumor. Using conventional criteria to identify mutations from a focal tissue specimen (e.g., variant allele frequency > 5%) undersamples glioblastoma’s broad clonal diversity, which ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7f0e36250d15d61703b21261e5e3620
https://doi.org/10.1093/neuonc/noz175.253
https://doi.org/10.1093/neuonc/noz175.253
Autor:
Hunter R. Underhill, Preetida J. Bhetariya, Sabine Hellwig, David A. Nix, Carrie L. Fuertes, Gabor T. Marth, Mary P. Bronner
Publikováno v:
Cancer Research. 79:441-441
Purpose: Challenges with distinguishing circulating tumor DNA from next-generation sequencing (NGS) artifacts limits variant searches to established solid tumor mutations. Identifying the source(s) of errors associated with the NGS analytics of circu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca49c48d8eb0ee216ef9f65c80ff5079
https://doi.org/10.1158/1538-7445.am2019-441
https://doi.org/10.1158/1538-7445.am2019-441
Autor:
David A Nix, Sabine Hellwig, Christopher Conley, Alun Thomas, Carrie L Fuertes, Cindy L Hamil, Preetida J Bhetariya, Ignacio Garrido-Laguna, Gabor T Marth, Mary P Bronner, Hunter R Underhill
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229063 (2020)
Challenges with distinguishing circulating tumor DNA (ctDNA) from next-generation sequencing (NGS) artifacts limits variant searches to established solid tumor mutations. Here we show early and random PCR errors are a principal source of NGS noise th
Externí odkaz:
https://doaj.org/article/5718b9aa273541e6820abd8340717128