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pro vyhledávání: '"Carrie L Rodriguez"'
Autor:
Amy E Schade, Ryan Kuzmickas, Carrie L Rodriguez, Kaia Mattioli, Miriam Enos, Alycia Gardner, Karen Cichowski
Publikováno v:
PLoS Biology, Vol 21, Iss 4, p e3002038 (2023)
While screening and early detection have reduced mortality from prostate cancer, castration-resistant disease (CRPC) is still incurable. Here, we report that combined EZH2/HDAC inhibitors potently kill CRPCs and cause dramatic tumor regression in agg
Externí odkaz:
https://doaj.org/article/cbbf2f8fe5bb48b684463c3b2ea4080e
Autor:
Amy Schade, Naiara Perurena, Marina Watanabe, Carrie L. Rodriguez, Patrick Loi, Natalie Pilla, Rachel A. Davis, Kaia Mattioli, Dongxi Xiang, Jason J. Zoeller, Zhe Li, Ana C. Garrido-Castro, Sara Tolaney, Karen Cichowski
Publikováno v:
Cancer Research. 83:P4-08
Triple negative breast cancer (TNBC) is the most aggressive breast cancer subtype and has the highest rate of recurrence. The predominant standard of care for advanced TNBC is systemic chemotherapy with or without immunotherapy, however responses are
Autor:
Naiara Perurena, Natalie Pilla, Amy Schade, Marina Watanabe, Patrick Loi, Carrie L. Rodriguez, Alycia M. Gardner, Karen Cichowski
Publikováno v:
Cancer Research. 83:P1-13
Resistance to HER2 inhibitors remains a clinical challenge in HER2+ breast cancer. Therefore, there is an urgent need to 1) understand the mechanisms that underlie resistance to these current treatments and 2) develop improved, and more importantly,