Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Carrie L Heusner"'
Autor:
Noah M Walton, Rick Shin, Katsunori Tajinda, Carrie L Heusner, Jeffrey H Kogan, Shinichi Miyake, Qian Chen, Kouichi Tamura, Mitsuyuki Matsumoto
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35264 (2012)
An increasing body of evidence suggests that alterations in neurogenesis and oxidative stress are associated with a wide variety of CNS diseases, including Alzheimer's disease, schizophrenia and Parkinson's disease, as well as routine loss of functio
Externí odkaz:
https://doaj.org/article/ea47c047cca740fe9aee274e17271dea
Autor:
Cynthia Shannon Weickert, D Sinclair, Carrie L. Heusner, Juan C Olaya, Mari Kondo, Mitsuyuki Matsumoto, Tim Karl
Publikováno v:
Schizophrenia Bulletin
Neuregulin 1 (NRG1) is a schizophrenia candidate gene whose protein product is involved in neuronal migration, survival, and synaptic plasticity via production of specific isoforms. Importantly, NRG1 type III (NRG1 III) mRNA is increased in humans in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977cdac1157b779629ef897fdc472d33
https://doi.org/10.1093/schbul/sbx122
https://doi.org/10.1093/schbul/sbx122
Publikováno v:
Behavioural brain research. 353
Elevated levels of the type III (III) isoforms of neuregulin 1 (NRG1) have been observed in the brains of schizophrenia patients that carry NRG1 HapICE risk alleles, which is thought to contribute to the aetiology of the disease. We generated transge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda3f635d161ffa6cfff9606e9b4fcf9
https://pubmed.ncbi.nlm.nih.gov/29559337
https://pubmed.ncbi.nlm.nih.gov/29559337
Autor:
Jeffrey H. Kogan, Shinichi Miyake, Anoek de Koning, Rick Shin, Noah M. Walton, Adam K. Gross, Kouichi Tamura, Katsunori Tajinda, Mitsuyuki Matsumoto, Xiuyuan Xie, Qian Chen, Carrie L. Heusner
Publikováno v:
Stem Cells, 32(9), 2454-2466. Wiley-Blackwell
Walton, N M, de Koning, A, Xie, X Y, Shin, R, Chen, Q, Miyake, S, Tajinda, K, Gross, A K, Kogan, J H, Heusner, C L, Tamura, K & Matsumoto, M 2014, ' Gastrin-Releasing Peptide Contributes to the Regulation of Adult Hippocampal Neurogenesis and Neuronal Development ', Stem Cells, vol. 32, no. 9, pp. 2454-2466 . https://doi.org/10.1002/stem.1740
Walton, N M, de Koning, A, Xie, X Y, Shin, R, Chen, Q, Miyake, S, Tajinda, K, Gross, A K, Kogan, J H, Heusner, C L, Tamura, K & Matsumoto, M 2014, ' Gastrin-Releasing Peptide Contributes to the Regulation of Adult Hippocampal Neurogenesis and Neuronal Development ', Stem Cells, vol. 32, no. 9, pp. 2454-2466 . https://doi.org/10.1002/stem.1740
In the postnatal hippocampus, newly generated neurons contribute to learning and memory. Disruptions in neurogenesis and neuronal development have been linked to cognitive impairment and are implicated in a broad variety of neurological and psychiatr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de7058b073ff885ab0bc4cc3fe40968
https://doi.org/10.1002/stem.1740
https://doi.org/10.1002/stem.1740
Autor:
Katsunori Kobayashi, Jeffrey H. Kogan, Shinichi Miyake, Kouichi Tamura, Tsuyoshi Miyakawa, Rick Shin, Adam K. Gross, Katsunori Tajinda, Noah M. Walton, Mitsuyuki Matsumoto, Carrie L. Heusner, Qian Chen, Hideo Hagihara
Publikováno v:
Bipolar Disorders
Shin R, Kobayashi K, Hagihara H, Kogan JH, Miyake S, Tajinda K,Walton NM, Gross AK, Heusner CL, Chen Q, Tamura K, Miyakawa T,Matsumoto M. The immature dentate gyrus represents a sharedphenotype of mouse models of epilepsy and psychiatric disease.Bipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6c22e7817dc9fd5f8d5fb0bb877a2a
http://europepmc.org/articles/PMC3752967
http://europepmc.org/articles/PMC3752967
Autor:
Qian Chen, Jeffrey H. Kogan, Shinichi Miyake, Yuan Zhou, Mitsuyuki Matsumoto, Carrie L. Heusner, Kouichi Tamura, Adam K. Gross, Katsunori Tajinda, Noah M. Walton, Rick Shin
Publikováno v:
The European Journal of Neuroscience
SREB2/GPR85, a member of the super-conserved receptor expressed in brain (SREB) family, is the most conserved G-protein-coupled receptor in vertebrate evolution. Previous human and mouse genetic studies have indicated a possible link between SREB2 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f4afb87bb66857b191537c612b5a93
https://doi.org/10.1111/j.1460-9568.2012.08180.x
https://doi.org/10.1111/j.1460-9568.2012.08180.x
Publikováno v:
genesis. 46:357-367
The medium spiny neurons (MSNs), which comprise the direct and indirect output pathways from the striatum, use γ-aminobutyric acid (GABA) as their major fact-acting neurotransmitter. We generated mice carrying a conditional allele of the Gad1 gene,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3c07c94f5200fa3670ba307e401737
https://doi.org/10.1002/dvg.20405
https://doi.org/10.1002/dvg.20405
Autor:
Kimberly R Thompson, Erin E. Gray, Kelsey C. Martin, Thomas J. O'Dell, Seth G. N. Grant, Carrie L. Heusner, Marcelo P. Coba, Christopher N. G. Anderson, Jary Y. Delgado
Publikováno v:
The Journal of Neuroscience. 27:13210-13221
Phosphorylation-dependent changes in AMPA receptor function have a crucial role in activity-dependent forms of synaptic plasticity such as long-term potentiation (LTP) and long-term depression (LTD). Although three previously identified phosphorylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d289005a8d680b2a5eabd62d5b3c23aa
https://doi.org/10.1523/jneurosci.3056-07.2007
https://doi.org/10.1523/jneurosci.3056-07.2007
Autor:
Amy Lin, Megumi Adachi, Mitsuyuki Matsumoto, Robert E. Featherstone, Qian Chen, Noah M. Walton, Katsunori Tajinda, Sosuke Miyoshi, Hiroyuki Ito, Carrie L. Heusner, Adam K. Gross, Rick Shin, Jeffrey H. Kogan, Shinichi Miyake, Steven J. Siegel
The chromosome 15q13.3 microdeletion is a pathogenic copy number variation conferring epilepsy, intellectual disability, schizophrenia, and autism spectrum disorder (ASD). We generated mice carrying a deletion of 1.2 Mb homologous to the 15q13.3 micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b961e5990fbcacafece151fa604098a1
https://europepmc.org/articles/PMC6605504/
https://europepmc.org/articles/PMC6605504/
Autor:
Ross Bland, David Weinshenker, Matthew During, Carrie L. Heusner, Richard D. Palmiter, Valerie G. Olson
Publikováno v:
Science. 311:1017-1020
Norepinephrine (NE) is widely implicated in opiate withdrawal, but much less is known about its role in opiate-induced locomotion and reward. In mice lacking dopamine β-hydroxylase (DBH), an enzyme critical for NE synthesis, we found that NE was nec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::796152c8e28ce8023cb5b05f04c26107
https://doi.org/10.1126/science.1119311
https://doi.org/10.1126/science.1119311