Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Carrie Brookner"'
Autor:
Seigo Suzuki, Carrie Brookner, Anais Malpica, Rebecca Richards-Kortum, Sharon Thomsen, Iouri Boiko, Javier Galvan, Michele Follen, Reuben Lotan
Publikováno v:
Photochemistry and Photobiology. 71:730-736
Fluorescence spectroscopy has potential to improve cervical precancer detection. The relationship between tissue biochemistry and fluorescence is poorly understood. The goal of this study was to characterize normal cervical autofluorescence, using fr
Autor:
Lezlee G Coghlan, Urs Utzinger, Irma B. Gimenez-Conti, Andres Zuluaga, Rebecca Richards-Kortum, Michele Follen, Carrie Brookner
Publikováno v:
Lasers in Surgery and Medicine. 29:1-10
Background and Objective: The hamster cheek pouch carcinogenesis model, using chronic treatments of dimethylbenz[a]anthracene (DMBA) was used as a model system to investigate changes in epithelial tissue autofluorescence throughout the dysplasia-carc
Autor:
Carrie Brookner, Reuben Lotan, Michele Follen, Anais Malpica, Tom Collier, Rebecca Richards-Kortum, Rebekah A. Drezek
Publikováno v:
American Journal of Obstetrics and Gynecology. 182:1135-1139
Objectives: The use of high-resolution in vivo confocal imaging may offer a clinically useful adjunct to standard methods for the diagnosis and screening of epithelial precancers. This study assesses the feasibility of real-time confocal reflectance
Autor:
Urs Utzinger, Scott B. Cantor, Michele Follen Mitchell, David Schottenfeld, Carrie Brookner, Rebecca Richards-Kortum
Publikováno v:
Obstetrics & Gynecology. 94:889-896
Objective: To evaluate the accuracy of fluorescence spectroscopy in screening for squamous intraepithelial lesions (SILs) and to compare its performance with that of Papanicolaou smear screening, colposcopy, cervicoscopy, cervicography, and human pap
Autor:
Michele Follen Mitchell, Rebecca Richards-Kortum, Urs Utzinger, Gregg A Staerkel, Carrie Brookner
Publikováno v:
Lasers in Surgery and Medicine. 24:29-37
Background and Objective: Cervical tissue fluorescence spectra have previously been measured in vivo in women with a recent abnormal Papanicolaou smear. Diagnostic algorithms have been developed to diagnose squamous intraepithelial lesions (SILs) bas
Autor:
Rebekah A. Drezek, Carrie Brookner, Lezlee G Coghlan, Douglas L. Heintzelman, Rebecca Richards-Kortum, Michele Follen, Andres Zuluaga, Urs Utzinger, Irma B. Gimenez-Conti
Publikováno v:
Optics express. 7(12)
Using the hamster cheek pouch carcinogenesis model, we explore which fluorescence excitation wavelengths are useful for the detection of neoplasia. 42 hamsters were treated with DMBA to induce carcinogenesis, and 20 control animals were treated only
Autor:
Michele Follen, Carrie Brookner, Iouri Boiko, Rebecca Richards-Kortum, Anais Malpica, Sharon Thomsen, Reuben Lotan
Publikováno v:
Biomedical Optical Spectroscopy and Diagnostics.
The goal of this study was to characterize the biological basis of cervical autofluorescence. Fluorescence of transverse fresh tissue slices was imaged using a fluorescence microscope. Fluorescence spectra were measured from cervical epithelial cell
Autor:
Urs Utzinger, Costas Pitris, Rebecca Richards-Kortum, Michele Follen Mitchell, Anant Agrawal, Carrie Brookner
Publikováno v:
Lasers in surgery and medicine. 25(3)
Background and Objective Fluorescence spectroscopy has been shown to provide information useful in the detection of cervical dysplasia. The goal of this study was to determine if substances found on the cervix such as acetic acid, mucus, and vaginal
Autor:
Rebekah A. Drezek, Costas Pitris, Rebecca Richards-Kortum, Carrie Brookner, Tom Collier, Urs Utzinger, Anant Agrawal, Colin L. Smithpeter, Michele Follen Mitchell
Publikováno v:
Biomedical Optical Spectroscopy and Diagnostics / Therapeutic Laser Applications.
Contrast agents are commonly applied to tissue in vitro and in vivo to aid in the extraction of diagnostically useful information from the sample. For example, staining techniques are commonly used to highlight cellular structures when using light mi
Autor:
Urs Utzinger, Rebecca Richards-Kortum, Lezlee G Coghlan, Carrie Brookner, Irma B. Gimenez-Conti, D. Weiss, Michele Follen Mitchell, Andres Zuluaga
Publikováno v:
Biomedical Optical Spectroscopy and Diagnostics / Therapeutic Laser Applications.
Fluorescence spectroscopy has been shown to be a viable technique for the diagnosis of epithelial dysplasia and neoplasia both in-vitro and in-vivo.1 Since excision and fixation change important characteristics of tissue such as vascularity and metab