Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Carrie A, Simpson"'
Autor:
Kelsi Swope, Josh Morton, Gregory P. Pogue, Leigh Burden, Nicholas Partain, Steve Hume, John Shepherd, Carrie A. Simpson, Miles B. Brennan, Thomas C. Furman, Sheila Kingrey-Gebe, Theresa Martinez, Jim McDonough, Michael H. Pauly, Kevin J. Whaley, Larry Zeitlin, Barry Bratcher, Hugh Haydon
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
The ongoing SARS-CoV-2 coronavirus pandemic of 2020–2021 underscores the need for manufacturing platforms that can rapidly produce monoclonal antibody (mAb) therapies. As reported here, a platform based on Nicotiana benthamiana produced mAb therape
Externí odkaz:
https://doaj.org/article/0444f122130744d095e196c092b78bd8
Autor:
Jennifer K. DeMarco, Joshua M. Royal, William E. Severson, Jon D. Gabbard, Steve Hume, Josh Morton, Kelsi Swope, Carrie A. Simpson, John W. Shepherd, Barry Bratcher, Kenneth E. Palmer, Gregory P. Pogue
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1346 (2021)
We developed a SARS-CoV-2 vaccine candidate (CoV-RBD121-NP) comprised of a tobacco mosaic virus-like nanoparticle conjugated to the receptor-binding domain of the spike glycoprotein of SARS-CoV-2 fused to a human IgG1 Fc domain. CoV-RBD121-NP elicits
Externí odkaz:
https://doaj.org/article/d948abd924354895b2c5b1c46d082bd9
Autor:
Joshua M. Royal, Carrie A. Simpson, Alison A. McCormick, Amanda Phillips, Steve Hume, Josh Morton, John Shepherd, Youngjun Oh, Kelsi Swope, Jennifer L. DeBeauchamp, Richard J. Webby, Robert W. Cross, Viktoriya Borisevich, Thomas W. Geisbert, Jennifer K. Demarco, Barry Bratcher, Hugh Haydon, Gregory P. Pogue
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1347 (2021)
Stable, effective, easy-to-manufacture vaccines are critical to stopping the COVID-19 pandemic resulting from the coronavirus SARS-CoV-2. We constructed a vaccine candidate CoV-RBD121-NP, which is comprised of the SARS-CoV-2 receptor-binding domain (
Externí odkaz:
https://doaj.org/article/43b61c27594a4cee8b9a7611a625c5e8
Autor:
Carrie L. Simpson
Publikováno v:
Transportation Research Record: Journal of the Transportation Research Board. 2677:753-762
The purpose of this project was to evaluate the safety effectiveness of Dynamic All-Red Extension (DARE) systems. North Carolina Department of Transportation has used DARE to combat red light running (RLR) crashes on major road approaches of selected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f223a84273f8752c143c8f822bbc65a
https://doi.org/10.1177/03611981221108386
https://doi.org/10.1177/03611981221108386
Publikováno v:
Transportation Research Record: Journal of the Transportation Research Board. :036119812211494
This study investigated the safety effects of the conversion from a protected-only left turn to protected-permissive left turn with flashing yellow arrow (FYA−PPLT) with time-of-day operation. The observational before–after study with the compari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb1a473c559318afa4740d4a37118e86
https://doi.org/10.1177/03611981221149430
https://doi.org/10.1177/03611981221149430
Autor:
Kelsi, Swope, Josh, Morton, Gregory P, Pogue, Steve, Hume, Michael H, Pauly, John, Shepherd, Carrie A, Simpson, Barry, Bratcher, Kevin J, Whaley, Larry, Zeitlin, Keith R, Davis, Hugh, Haydon
Publikováno v:
Methods in enzymology. 660
Monoclonal antibodies (mAbs) hold great promise for treating diseases ranging from cancer to infectious disease. Manufacture of mAbs is challenging, expensive, and time-consuming using mammalian systems. We describe detailed methods used by Kentucky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2dd51b13b1765289cec7315a4129cef7
https://pubmed.ncbi.nlm.nih.gov/34742392
https://pubmed.ncbi.nlm.nih.gov/34742392
Autor:
Samuel K. Lai, Bhawana Shrestha, Thomas R. Moench, Massoud Motamedi, Henry Pham, Michael H. Pauly, Josh Morton, Gracie Vargas, Kevin J. Whaley, Larry Zeitlin, Carrie A. Simpson, Alison Schaefer, Kelsi Swope, Kathleen L. Vincent, Yong Zhu, Miles B. Brennan, Barry Bratcher
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Nearly half of all pregnancies in the United States are unintended due to millions of women avoiding available hormonal contraceptive methods as a result of real and/or perceived side effects associated with the use of exogenous hormones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5e68710949be7983f8592853a85da6d
http://europepmc.org/articles/PMC8640842
http://europepmc.org/articles/PMC8640842
Autor:
Gregory P. Pogue, Steve Hume, Jennifer K. DeMarco, Josh Morton, John W. Shepherd, Jon D. Gabbard, Joshua M. Royal, Kelsi Swope, Barry Bratcher, Kenneth E. Palmer, William Severson, Carrie A. Simpson
Publikováno v:
Vaccines
Vaccines, Vol 9, Iss 1346, p 1346 (2021)
Volume 9
Issue 11
Vaccines, Vol 9, Iss 1346, p 1346 (2021)
Volume 9
Issue 11
We developed a SARS-CoV-2 vaccine candidate (CoV-RBD121-NP) comprised of a tobacco mosaic virus-like nanoparticle conjugated to the receptor-binding domain of the spike glycoprotein of SARS-CoV-2 fused to a human IgG1 Fc domain. CoV-RBD121-NP elicits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b329a7578b16d5aa6c0a5474182ec467
https://pubmed.ncbi.nlm.nih.gov/34835277
https://pubmed.ncbi.nlm.nih.gov/34835277
Autor:
Kevin J. Whaley, Barry Bratcher, Hugh Haydon, Carrie A. Simpson, Josh Morton, Keith R. Davis, Gregory P. Pogue, Michael H. Pauly, Steve Hume, Kelsi Swope, Larry Zeitlin, John W. Shepherd
Publikováno v:
Methods in Enzymology ISBN: 9780323907378
Monoclonal antibodies (mAbs) hold great promise for treating diseases ranging from cancer to infectious disease. Manufacture of mAbs is challenging, expensive, and time-consuming using mammalian systems. We describe detailed methods used by Kentucky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aecff14492cc9515dbb7d65a83a54b4
https://doi.org/10.1016/bs.mie.2021.05.011
https://doi.org/10.1016/bs.mie.2021.05.011
Autor:
Hugh Haydon, Amanda Phillips, Gregory P. Pogue, Robert W. Cross, Steve Hume, Joshua M. Royal, Jennifer DeBeauchamp, Thomas W. Geisbert, Josh Morton, Alison A. McCormick, John W. Shepherd, Carrie A. Simpson, Viktoriya Borisevich, Barry Bratcher, Jennifer K. DeMarco, Richard J. Webby, Kelsi Swope, Young Jun Oh
Publikováno v:
Vaccines, Vol 9, Iss 1347, p 1347 (2021)
Vaccines
Volume 9
Issue 11
Vaccines
Volume 9
Issue 11
Stable, effective, easy-to-manufacture vaccines are critical to stopping the COVID-19 pandemic resulting from the coronavirus SARS-CoV-2. We constructed a vaccine candidate CoV-RBD121-NP, which is comprised of the SARS-CoV-2 receptor-binding domain (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6906ad3b34797bf0600d09a380a93f8
https://doi.org/10.3390/vaccines9111347
https://doi.org/10.3390/vaccines9111347