Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Carrie, Cartwright"'
Autor:
Henry Hiep Vo, Siqing Fu, David S. Hong, Daniel D. Karp, Sarina Piha-Paul, Vivek Subbiah, Filip Janku, Aung Naing, Timothy A. Yap, Jordi Rodon, Jaffer A. Ajani, Carrie Cartwright, Amber Johnson, I-Wen Song, Jennifer Beck, Michael Kahle, Graciela M. Nogueras-Gonzalez, Vincent Miller, Calvin Chao, David J. Vining, Donald A. Berry, Funda Meric-Bernstam, Apostolia-Maria Tsimberidou
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-12 (2022)
Abstract We investigated the challenges of conducting IMPACT2, an ongoing randomized study that evaluates molecular testing and targeted therapy (ClinicalTrials.gov: NCT02152254). Patients with metastatic cancer underwent tumor profiling and were ran
Externí odkaz:
https://doaj.org/article/0dcfdec9f8b24bf8a8a6b4c9cca14e08
Autor:
Apostolia Maria Tsimberidou, David S. Hong, Siqing Fu, Daniel D. Karp, Sarina Piha-Paul, Merrill S. Kies, Vinod Ravi, Vivek Subbiah, Sunil M. Patel, Shi-Ming Tu, Filip Janku, John Heymach, Amber Johnson, Carrie Cartwright, Li Zhao, Jianhua Zhang, Donald A. Berry, David J. Vining, Andrew Futreal, Vincent A. Miller, Funda Meric-Bernstam
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-9 (2021)
Abstract Precision medicine is associated with favorable outcomes in selected patients with cancer. Herein, we report an interim analysis of IMPACT2, an ongoing randomized study evaluating genomic profiling and targeted agents in metastatic cancer. P
Externí odkaz:
https://doaj.org/article/33315794ca1f4daf8eba5da8574c8e3f
Autor:
Apostolia-Maria Tsimberidou, David S. Hong, Jennifer J. Wheler, Gerald S. Falchook, Filip Janku, Aung Naing, Siqing Fu, Sarina Piha-Paul, Carrie Cartwright, Russell R. Broaddus, Graciela M. Nogueras Gonzalez, Patrick Hwu, Razelle Kurzrock
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-12 (2019)
Abstract Background In 2007, we initiated IMPACT, a precision medicine program for patients referred for participation in early-phase clinical trials. We assessed the correlation of factors, including genomically matched therapy, with overall surviva
Externí odkaz:
https://doaj.org/article/104ff192ed164bfea419fe086138f71a
Autor:
Robert A. Newman, Norma Llansa, Gabriela Mendoza, Milind Suraokar, Susan Dixon, Diana Chan, Carrie Cartwright, David G. Menter, Peiying Yang
Cardiac glycosides such as oleandrin are known to inhibit the Na,K-ATPase pump, resulting in a consequent increase in calcium influx in heart muscle. Here, we investigated the effect of oleandrin on the growth of human and mouse cancer cells in relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d3f3adcc2a8217533ed701ca41c3ea
https://doi.org/10.1158/1535-7163.c.6532020
https://doi.org/10.1158/1535-7163.c.6532020
Autor:
Robert A. Newman, Norma Llansa, Gabriela Mendoza, Milind Suraokar, Susan Dixon, Diana Chan, Carrie Cartwright, David G. Menter, Peiying Yang
Supplementary Figures 1-3 from Oleandrin-mediated inhibition of human tumor cell proliferation: Importance of Na,K-ATPase α subunits as drug targets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511390b3a9a2f4e0140a8fb3090bab28
https://doi.org/10.1158/1535-7163.22485597
https://doi.org/10.1158/1535-7163.22485597
Autor:
Apostolia Maria Tsimberidou, Cara Haymaker, Franck Alexandre Silva, Simin Kiany, Kemal Haque, Lucy Coe, Carrie Cartwright, Helen Berryman, Graciela M. Nogueras-Gonzalez, James Dow, David Vining, Alexander Richard Liam Cecil, Henry H. Vo, Elisabeth A. Bone, Ignacio I. Wistuba, Philip A. Beer, Hilary McElwaine-Johnn
Publikováno v:
Clinical Cancer Research. 27:3584-3594
Purpose: Inhibition of histone deacetylase 6 (HDAC6) is predicted to deliver both direct antitumor activity and modulation of the antitumor immune response. This study describes the development of a novel HDAC6 inhibitor. Patients and Methods: KA2507
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa6f156927db60cbf7c47ada3193d33
https://doi.org/10.1158/1078-0432.ccr-21-0238
https://doi.org/10.1158/1078-0432.ccr-21-0238
Autor:
Vivek Subbiah, Vinod Ravi, John V. Heymach, Sunil M. Patel, Jianhua Zhang, Funda Meric-Bernstam, David S. Hong, Shi-Ming Tu, Andrew Futreal, Vincent A. Miller, Filip Janku, Merrill S. Kies, Daniel D. Karp, Donald A. Berry, Amber Johnson, Siqing Fu, Sarina Anne Piha-Paul, Carrie Cartwright, Li Zhao, David Vining, Apostolia Maria Tsimberidou
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-9 (2021)
NPJ Precision Oncology
NPJ Precision Oncology
Precision medicine is associated with favorable outcomes in selected patients with cancer. Herein, we report an interim analysis of IMPACT2, an ongoing randomized study evaluating genomic profiling and targeted agents in metastatic cancer. Patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::347035b1d4151d65e40b20dbc911fab1
https://doaj.org/article/33315794ca1f4daf8eba5da8574c8e3f
https://doaj.org/article/33315794ca1f4daf8eba5da8574c8e3f
Autor:
Henry Hiep Vo, Carrie Cartwright, I-Wen Song, Daniel D. Karp, Graciela M. Nogueras Gonzalez, Yuran Xie, Michael Karol, Matthew Hitron, David Vining, Apostolia-Maria Tsimberidou
Publikováno v:
Cancers; Volume 14; Issue 5; Pages: 1330
Background: BBI608 is an investigational reactive oxygen species generator that affects several molecular pathways. We investigated BBI608 combined with immune checkpoint inhibitors in patients with advanced cancers. Methods: BBI608 (orally twice dai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae5581e29a81ee609ad2aa515d96099
https://pubmed.ncbi.nlm.nih.gov/35267638
https://pubmed.ncbi.nlm.nih.gov/35267638
Autor:
Peiying Yang, Diana Chan, Edward Felix, Carrie Cartwright, David G. Menter, Timothy Madden, Russell D. Klein, Susan M. Fischer, Robert A. Newman
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 6, Pp 1030-1039 (2004)
We investigated the formation and pharmacology of prostaglandin E3 (PGE3) derived from fish oil eicosapentaenoic acid (EPA) in human lung cancer A549 cells. Exposure of A549 cells to EPA resulted in the rapid formation and export of PGE3. The extrace
Externí odkaz:
https://doaj.org/article/50cde462146242a39d107374454ab371
Autor:
Siqing Fu, Russell Broaddus, Sarina Anne Piha-Paul, Gerald S. Falchook, Jennifer J. Wheler, Carrie Cartwright, Razelle Kurzrock, Patrick Hwu, David S. Hong, Apostolia Maria Tsimberidou, Aung Naing, Graciela M. Nogueras González, Filip Janku
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-12 (2019)
Journal of Hematology & Oncology
Journal of Hematology & Oncology
Background In 2007, we initiated IMPACT, a precision medicine program for patients referred for participation in early-phase clinical trials. We assessed the correlation of factors, including genomically matched therapy, with overall survival (OS). P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0bee9037c99e4ef64308a1eaa4ac6bf
https://doi.org/10.1186/s13045-019-0835-1
https://doi.org/10.1186/s13045-019-0835-1