SARS-CoV-2 infection, inflammation and birth outcomes in a prospective NYC pregnancy cohort.

Autor: Gigase FAJ; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA; Department of Child and Adolescent Psychiatry, Erasmus Medical Center, Rotterdam, the Netherlands. Electronic address: f.gigase@erasmusmc.nl., Jessel RH; Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York City, NY, USA; Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Kaplowitz E; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Boychuk N; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Ohrn S; Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Ibroci E 1st; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Castro J; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Lynch J; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Tubassum R; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Balbierz A; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Molenaar NM; Department of Psychiatry, Erasmus Medical Center, Rotterdam, the Netherlands., Graziani M; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Missall R; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Flores T; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Stern T; Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Carreno JM; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY, USA., Krammer F; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY, USA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY, USA., Adler A; Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Brody RI; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Lesseur C; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Chen J; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Ellington S; COVID-19 Response, Centers for Disease Control and Prevention, Atlanta, GA, USA., Galang RR; COVID-19 Response, Centers for Disease Control and Prevention, Atlanta, GA, USA., Snead MC; COVID-19 Response, Centers for Disease Control and Prevention, Atlanta, GA, USA., Howell E; Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York City, NY, USA; Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Stone J; Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Bergink V; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA; Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York City, NY, USA; Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Dolan S; Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Lieb W; Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York City, NY, USA; Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York City, NY, USA; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Rommel AS; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., de Witte LD; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., Janevic T; Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York City, NY, USA; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

Publikováno v: Journal of reproductive immunology [J Reprod Immunol] 2024 Jun; Vol. 163, pp. 104243. Date of Electronic Publication: 2024 Mar 18.

Study of efficacy and longevity of immune response to third and fourth doses of COVID-19 vaccines in patients with cancer: A single arm clinical trial.

Autor: Thakkar A; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States., Pradhan K; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, United States., Duva B; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States., Carreno JM; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, United States.; Center for Vaccine Research and Pandemic Preparedness (C-VARPP), Icahn School of Medicine at Mount Sinai, New York, United States., Sahu S; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States., Thiruthuvanathan V; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States., Campbell S; Department of Pathology, Montefiore Medical Center, Bronx, United States., Gallego S; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States., Bhagat TD; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States., Rivera J; Department of Medicine, Albert Einstein College of Medicine, Bronx, United States., Choudhary G; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States., Olea R; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States., Sabalza M; Euroimmun, Mountain Lakes, United States., Shapiro LC; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States., Lee M; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States., Quinn R; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States., Mantzaris I; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States., Chu E; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States., Will B; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States., Pirofski LA; Department of Medicine, Albert Einstein College of Medicine, Bronx, United States., Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, United States.; Center for Vaccine Research and Pandemic Preparedness (C-VARPP), Icahn School of Medicine at Mount Sinai, New York, United States.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, United States., Verma A; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States., Halmos B; Department of Oncology, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, United States.

Publikováno v: ELife [Elife] 2023 Mar 28; Vol. 12. Date of Electronic Publication: 2023 Mar 28.

The plasmablast response to SARS-CoV-2 mRNA vaccination is dominated by non-neutralizing antibodies and targets both the NTD and the RBD.

Autor: Amanat F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Thapa M; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, 63110, USA., Lei T; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, 63110, USA., Sayed Ahmed SM; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, 63110, USA., Adelsberg DC; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Carreno JM; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Strohmeier S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Schmitz AJ; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, 63110, USA., Zafar S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Zhou JQ; AbCellera Biologics Inc., Vancouver, BC V5Y 0A1, Canada., Rijnink W; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Alshammary H; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Borcherding N; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, 63110, USA., Reiche AG; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Srivastava K; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, 63110, USA.; AbCellera Biologics Inc., Vancouver, BC V5Y 0A1, Canada.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; The Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, Saint Louis, MO 63110, USA., Sordillo EM; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., van Bakel H; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Turner JS; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, 63110, USA., Bajic G; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Simon V; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; The Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Ellebedy AH; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, 63110, USA.; Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, Saint Louis, MO 63110, USA., Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2021 May 01. Date of Electronic Publication: 2021 May 01.