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Amylovis-201 is a new dual-target ligand, acting as an anti-amyloidogenic compound and a potent agonist of the σ 1 chaperone protein.

Autor: García-Pupo L; Department of Neurochemistry, Cuban Center for Neurosciences, Cubanacan, Playa, Havana CP 11600, Cuba., Crouzier L; MMDN, University of Montpellier, EPHE, INSERM, Montpellier 34095, France., Bencomo-Martínez A; Department of Neurochemistry, Cuban Center for Neurosciences, Cubanacan, Playa, Havana CP 11600, Cuba., Meunier J; MMDN, University of Montpellier, EPHE, INSERM, Montpellier 34095, France., Morilleau A; MMDN, University of Montpellier, EPHE, INSERM, Montpellier 34095, France., Delprat B; MMDN, University of Montpellier, EPHE, INSERM, Montpellier 34095, France., Carrazana MS; Department of Neurochemistry, Cuban Center for Neurosciences, Cubanacan, Playa, Havana CP 11600, Cuba., Menéndez Soto Del Valle R; Department of Neurochemistry, Cuban Center for Neurosciences, Cubanacan, Playa, Havana CP 11600, Cuba., Maurice T; MMDN, University of Montpellier, EPHE, INSERM, Montpellier 34095, France., Rodríguez-Tanty C; Department of Neurochemistry, Cuban Center for Neurosciences, Cubanacan, Playa, Havana CP 11600, Cuba.

Publikováno v: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2024 Oct; Vol. 14 (10), pp. 4345-4359. Date of Electronic Publication: 2024 Jun 20.