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Potential Use of Senolytics for Pharmacological Targeting of Precancerous Lesions.

Autor: Saleh T; Department of Basic Medical Sciences, Faculty of Medicine, Hashemite University, Zarqa, Jordan (T.S.); Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, Virginia (V.J.C.) tareq@hu.edu.jo., Carpenter VJ; Department of Basic Medical Sciences, Faculty of Medicine, Hashemite University, Zarqa, Jordan (T.S.); Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, Virginia (V.J.C.).

Publikováno v: Molecular pharmacology [Mol Pharmacol] 2021 Dec; Vol. 100 (6), pp. 580-587. Date of Electronic Publication: 2021 Sep 20.

HIV-1 Tat and Morphine Differentially Disrupt Pyramidal Cell Structure and Function and Spatial Learning in Hippocampal Area CA1: Continuous versus Interrupted Morphine Exposure.

Autor: Marks WD; Department of Pharmacology and Toxicology, Virginia Commonwealth University, School of Medicine, Richmond, VA 23298-0613., Paris JJ; Department of BioMolecular Sciences, University of Mississippi, School of Pharmacy, University, MS 38677-1848., Barbour AJ; Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, VA 23298-0709., Moon J; Department of Pharmacology and Toxicology, Virginia Commonwealth University, School of Medicine, Richmond, VA 23298-0613., Carpenter VJ; Department of Pharmacology and Toxicology, Virginia Commonwealth University, School of Medicine, Richmond, VA 23298-0613., McLane VD; Department of Pharmacology and Toxicology, Virginia Commonwealth University, School of Medicine, Richmond, VA 23298-0613., Lark ARS; Department of Pharmacology and Toxicology, Virginia Commonwealth University, School of Medicine, Richmond, VA 23298-0613., Nass SR; Department of Pharmacology and Toxicology, Virginia Commonwealth University, School of Medicine, Richmond, VA 23298-0613., Zhang J; Department of Pharmacology and Toxicology, Virginia Commonwealth University, School of Medicine, Richmond, VA 23298-0613., Yarotskyy V; Department of Pharmacology and Toxicology, Virginia Commonwealth University, School of Medicine, Richmond, VA 23298-0613., McQuiston AR; Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, VA 23298-0709., Knapp PE; Department of Pharmacology and Toxicology, Virginia Commonwealth University, School of Medicine, Richmond, VA 23298-0613.; Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, VA 23298-0709.; Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, VA 23298-0709., Hauser KF; Department of Pharmacology and Toxicology, Virginia Commonwealth University, School of Medicine, Richmond, VA 23298-0613 kurt.hauser@vcuhealth.org.; Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, VA 23298-0709.; Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, VA 23298-0709.

Publikováno v: ENeuro [eNeuro] 2021 May 24; Vol. 8 (3). Date of Electronic Publication: 2021 May 24 (Print Publication: 2021).

Senescence and castration resistance in prostate cancer: A review of experimental evidence and clinical implications.

Autor: Carpenter VJ; Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA., Patel BB; Department of Internal Medicine, Division of Hematology, Oncology & Palliative Care, VCU Health, Richmond, VA, USA., Autorino R; Department of Surgery, Division of Urology, VCU Health, Richmond, VA, USA., Smith SC; Department of Pathology, VCU Health, Richmond, VA, USA., Gewirtz DA; Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA., Saleh T; The Department of Basic Medical Sciences, Faculty of Medicine, The Hashemite University, Zarqa, Jordan. Electronic address: tareq@hu.edu.jo.

Publikováno v: Biochimica et biophysica acta. Reviews on cancer [Biochim Biophys Acta Rev Cancer] 2020 Dec; Vol. 1874 (2), pp. 188424. Date of Electronic Publication: 2020 Sep 18.

Therapy-Induced Senescence: An "Old" Friend Becomes the Enemy.

Autor: Saleh T; The Department of Basic Medical Sciences, Faculty of Medicine, The Hashemite University, Zarqa 13133, Jordan., Bloukh S; Department of Pathology, Microbiology and Forensic Medicine, School of Medicine, The University of Jordan, Amman 11942, Jordan., Carpenter VJ; Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA 23284, USA., Alwohoush E; Department of Pathology, Microbiology and Forensic Medicine, School of Medicine, The University of Jordan, Amman 11942, Jordan., Bakeer J; Department of Pathology, Microbiology and Forensic Medicine, School of Medicine, The University of Jordan, Amman 11942, Jordan., Darwish S; The Department of Basic Medical Sciences, Faculty of Medicine, The Hashemite University, Zarqa 13133, Jordan., Azab B; Department of Pathology, Microbiology and Forensic Medicine, School of Medicine, The University of Jordan, Amman 11942, Jordan.; Department of Human and Molecular Genetics, School of Medicine, Virginia Commonwealth University, Richmond, VA 23284, USA., Gewirtz DA; Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA 23284, USA.

Publikováno v: Cancers [Cancers (Basel)] 2020 Mar 29; Vol. 12 (4). Date of Electronic Publication: 2020 Mar 29.