Výsledky vyhledávání - "Carolynne Ricardo"

Akademický článek

Cellular mechanism of action of 2-nitroimidazoles as hypoxia-selective therapeutic agents

Autor: Faisal Bin Rashed, Diana Diaz-Dussan, Fatemeh Mashayekhi, Dawn Macdonald, Patrick Nicholas Nation, Xiao-Hong Yang, Sargun Sokhi, Alexandru Cezar Stoica, Hassan El-Saidi, Carolynne Ricardo, Ravin Narain, Ismail Hassan Ismail, Leonard Irving Wiebe, Piyush Kumar, Michael Weinfeld

Publikováno v: Redox Biology, Vol 52, Iss , Pp 102300- (2022)

Solid tumours are often poorly oxygenated, which confers resistance to standard treatment modalities. Targeting hypoxic tumours requires compounds, such as nitroimidazoles (NIs), equipped with the ability to reach and become activated within diffusio

Externí odkaz: https://doaj.org/article/ca3feb48a8764c959214901ce3f5c81e

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Akademický článek

Corrigendum to ‘Identification of proteins and cellular pathways targeted by 2-nitroimidazole hypoxic cytotoxins’ [Redox Biol. 41 (2021) 101905]

Autor: Faisal Bin Rashed, Alexandru Cezar Stoica, Dawn MacDonald, Hassan El-Saidi, Carolynne Ricardo, Bhumi Bhatt, Jack Moore, Diana Diaz-Dussan, Nirilanto Ramamonjisoa, Yvonne Mowery, Sambasivarao Damaraju, Richard Fahlman, Piyush Kumar, Michael Weinfeld

Publikováno v: Redox Biology, Vol 44, Iss , Pp 101986- (2021)

Externí odkaz: https://doaj.org/article/389dcf357e7845c4bf93640e9c31345d

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Akademický článek

Identification of proteins and cellular pathways targeted by 2-nitroimidazole hypoxic cytotoxins

Publikováno v: Redox Biology, Vol 41, Iss , Pp 101905- (2021)

Tumour hypoxia negatively impacts therapy outcomes and continues to be a major unsolved clinical problem. Nitroimidazoles are hypoxia selective compounds that become entrapped in hypoxic cells by forming drug-protein adducts. They are widely used as

Externí odkaz: https://doaj.org/article/acd2f8f486bc4b74a03fa90d0932af06

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Synthesis of Functionalized Polytriazoles via One-Pot Sequential Copper-Catalyzed Azide-Alkyne [3+2] Cycloaddition and Atom Transfer Radical Addition (ATRA)

Autor: Carolynne Ricardo, Tomislav Pintauer

Publikováno v: Israel Journal of Chemistry. 52:320-327

As a continuing effort of expanding the scope of catalyst regeneration in the presence of environmentally benign reducing agents, one-pot sequential azide–alkyne [3+2] cycloaddition and atom transfer radical addition (ATRA) reactions were performed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::762f1f45397864ae8c3a230ca5eb8950
https://doi.org/10.1002/ijch.201100111

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One‐Pot Sequential Azide–Alkyne [3+2] Cycloaddition and Atom Transfer Radical Addition (ATRA): Expanding the Scope of In Situ Copper(I) Regeneration in the Presence of Environmentally Benign Reducing Agent

Autor: Carolynne Ricardo, Tomislav Pintauer

Publikováno v: European Journal of Inorganic Chemistry. 2011:1292-1301

One-pot sequential reactions involving azide–alkyne [3+2] cycloaddition and atom transfer radical addition (ATRA) catalyzed by [CuII(TPMA)X][X] {X = Br– or Cl–, TPMA = tris(2-pyridylmethyl)amine} in the presence of ascorbic acid as a reducing a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6909cc9f118ef52582d15d521bac315c
https://doi.org/10.1002/ejic.201001335

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Strong Coordination of Tetraphenylborate Anion to Copper(I) Bipyridine and Phenanthroline-Based Complexes and Its Effect on Catalytic Activity in the Cyclopropanation of Styrene

Autor: Jeffrey D. Evanseck, Lauren M. Matosziuk, Tomislav Pintauer, Carolynne Ricardo

Publikováno v: Inorganic Chemistry. 48:16-18

The synthesis, characterization, and cyclopropanation activity of tetrahedral copper(I) complexes with bipyridine- and phenanthroline-based ligands containing strongly coordinated tetraphenylborate anions are reported. Cu(I)(bpy)(BPh(4)), Cu(I)(phen)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f1dcf94ed3bb9a6ec0f67b7a47fc9d
https://doi.org/10.1021/ic801783r

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Highly Efficient Organic and Macromolecular Synthesis Using Sequential Copper Catalyzed Azide-Alkyne [3+2] Cycloaddition and ATRA/ATRP

Autor: Tomislav Pintauer, Carolynne Ricardo

Publikováno v: ACS Symposium Series ISBN: 9780841226999
ACS Symposium Series

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5cda01e252bcc6d14aa162a9f7903bd2
https://doi.org/10.1021/bk-2012-1100.ch006

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ChemInform Abstract: Copper Catalyzed Atom Transfer Radical Cascade Reactions in the Presence of Free-Radical Diazo Initiators as Reducing Agents

Autor: Carolynne Ricardo, Tomislav Pintauer

Publikováno v: ChemInform. 40

Exceptional activity of [Cu(II)(TPMA)Cl][Cl] (TPMA = tris(2-pyridylmethyl)amine) complex in atom transfer radical addition (ATRA) of CCl(4) to 1,6-dienes followed by sequential atom transfer radical cyclization (ATRC) in the presence of free-radical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::306778b9304386e46f244d7e8c11d896
https://doi.org/10.1002/chin.200941034

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Highly efficient ambient-temperature copper-catalyzed atom-transfer radical addition (ATRA) in the presence of free-radical initiator (V-70) as a reducing agent

Autor: Matthew J. W. Taylor, Marielle Nicole C. Balili, Carolynne Ricardo, Ashley B. Biernesser, Sean J. Noonan, William T. Eckenhoff, Tomislav Pintauer

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany). 15(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe4d70bfe985e5037eecb07996d4ca9
https://pubmed.ncbi.nlm.nih.gov/19034944

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Copper catalyzed atom transfer radical cascade reactions in the presence of free-radical diazo initiators as reducing agents

Autor: Carolynne Ricardo, Tomislav Pintauer

Publikováno v: Chemical Communications. :3029

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd70978b0c27b375cc7dbded57adc734
https://doi.org/10.1039/b905839g

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