Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Carolyne Bardeleben"'
Autor:
Yijiang Shi, Patrick Frost, Bao Hoang, Yonghui Yang, Carolyne Bardeleben, Joseph Gera, Alan Lichtenstein
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94011 (2014)
Because multiple myeloma (MM) cells are at risk for endoplasmic reticulum (ER) stress, they require a carefully regulated mechanism to promote protein translation of selected transcripts when proliferation is stimulated. MAPK-interacting kinases (MNK
Externí odkaz:
https://doaj.org/article/afbb6a8ed1804a6b8aca5b065b7ec90c
Autor:
Alan Lichtenstein, Carolyne Bardeleben, Veena Mysore, Patrick J. Frost, Yijiang Shi, Bao Hoang
Suppl fig 7: A) MM1.S MM cells transfected with empty vector (ev) or wild type SGK (sgk) subsequently treated with 0, 10 or 20 nM Bortezomib for 8 hrs followed by immunoblot assay.; B) MM cells uninfected (par=parental) or infected with shRNA targeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34078e49608ae84c4431aa198eac82d1
https://doi.org/10.1158/1541-7786.22514134
https://doi.org/10.1158/1541-7786.22514134
Autor:
Alan Lichtenstein, Yijiang Shi, Bao Hoang, Patrick Frost, Sara Bassilian, Joseph R. Reeve, Sanjai Sharma, Carolyne Bardeleben
PDF file - 82K, Cell cycle analysis of cells treated with AICAr in the presence or absence of uridine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8e7e86fdfe5eb830a83bde205b7d66
https://doi.org/10.1158/1535-7163.22500717
https://doi.org/10.1158/1535-7163.22500717
Autor:
Alan Lichtenstein, Carolyne Bardeleben, Veena Mysore, Patrick J. Frost, Yijiang Shi, Bao Hoang
Suppl fig 3: A) MM1.S or 8226 cells lines transfected with empty vector (EV), wild type SGK (sgk) or phosphomimetic SGK (sgk422D) and cultured in serum free media for days 1-7. At designated days, apoptosis assay performed. Data are percent apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea795254c9451fc10962b7d12113461
https://doi.org/10.1158/1541-7786.22514146
https://doi.org/10.1158/1541-7786.22514146
Autor:
Alan Lichtenstein, Carolyne Bardeleben, Veena Mysore, Patrick J. Frost, Yijiang Shi, Bao Hoang
Suppl fig 2 ) MM1.S or OPM-2 MM cells stably transfected with empty vector (ev), wild type AKT (akt), phosphomimetic AKT, (akt473d), wild type SGK (sgk) or Phosphomimetic SGK (sgk422d), challenged with pp242 (left panels) or torin (right panels) foll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38421546fb8cf0ba25e9f24495dde3ee
https://doi.org/10.1158/1541-7786.22514149.v1
https://doi.org/10.1158/1541-7786.22514149.v1
Autor:
Alan Lichtenstein, Yijiang Shi, Bao Hoang, Patrick Frost, Sara Bassilian, Joseph R. Reeve, Sanjai Sharma, Carolyne Bardeleben
PDF file - 2312K, Heat map and table of metabolites of significantly altered metabolites in AICAr-treated samples for rapamycin treated samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4179fe972c7cd324562d1526f331b7
https://doi.org/10.1158/1535-7163.22500723.v1
https://doi.org/10.1158/1535-7163.22500723.v1
Autor:
Alan Lichtenstein, Carolyne Bardeleben, Veena Mysore, Patrick J. Frost, Yijiang Shi, Bao Hoang
Suppl fig 6: Combination indices (CIs) and fraction affected in 8226 cells treated with either bortezomib +/- SGK inhibitor (in A) or Staurosporine +/- SGK inhibitor (in B). CIs determined from apoptosis data of 4 independent experiments using mean v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be0fdb53e801b6c6af674fd658fcce4
https://doi.org/10.1158/1541-7786.22514137
https://doi.org/10.1158/1541-7786.22514137
Autor:
Alan Lichtenstein, Yijiang Shi, Bao Hoang, Patrick Frost, Sara Bassilian, Joseph R. Reeve, Sanjai Sharma, Carolyne Bardeleben
PDF file - 64K, Chemical structure of bortezomib, melphalan and metformin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d791c443798d093c7a32dceb1f31f4
https://doi.org/10.1158/1535-7163.22500729
https://doi.org/10.1158/1535-7163.22500729
Autor:
Alan Lichtenstein, Carolyne Bardeleben, Veena Mysore, Patrick J. Frost, Yijiang Shi, Bao Hoang
Suppl fig 5: SGK protein stability in 8226 cells treated +/- bortezomib (20nM); Data are Mean+/-SD, n=3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2dcd1f05b1307b368852bd1915a9d4
https://doi.org/10.1158/1541-7786.22514140
https://doi.org/10.1158/1541-7786.22514140
Autor:
Alan Lichtenstein, Carolyne Bardeleben, Veena Mysore, Patrick J. Frost, Yijiang Shi, Bao Hoang
Suppl fig 4: Lysate harvested from tumors of mice challenged with EV- or SGK-transfected tumors and treated with 0, 0.5 or 1 mg/kg Bortezomib; Lysates are combined from 3 mice/group and harvested 1 week after initiating treatment (mice had received 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e98007663728663e2f1ae50e30f7e3
https://doi.org/10.1158/1541-7786.22514143.v1
https://doi.org/10.1158/1541-7786.22514143.v1