Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Carolyne B. Braga"'
Autor:
Gagan Sharma, Carolyne B. Braga, Kai-En Chen, Xinying Jia, Venkatraman Ramanujam, Brett M. Collins, Roberto Rittner, Mehdi Mobli
Publikováno v:
Current Research in Structural Biology, Vol 3, Iss , Pp 179-186 (2021)
Chlorotoxin (ClTx) is a 36-residue disulfide-rich peptide isolated from the venom of the scorpion Leiurus quinquestriatus. This peptide has been shown to selectively bind to brain tumours (gliomas), however, with conflicting reports regarding its dir
Externí odkaz:
https://doaj.org/article/af52d3404ddf4994b4ff881afbc923be
Autor:
Gabriel Perli, Diego L. Bertuzzi, Dênio E. P. Souto, Miguel D. Ramos, Carolyne B. Braga, Samile B. Aguiar, Catia Ornelas
Publikováno v:
Nanomaterials, Vol 12, Iss 15, p 2610 (2022)
Dendronized gold nanoparticles (AuNPs) were synthesized bearing charged peripheral groups. Two novel AB3-type dendrons were synthesized with a thiol group at the focal point followed by their attachment to AuNPs. Dendrons were designed to have nine c
Externí odkaz:
https://doaj.org/article/f632eeb08beb4a84b1b714e8e3ac054d
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 925-937 (2017)
The understanding of the conformational behavior of amino acids and their derivatives is a challenging task. Here, the conformational analysis of esterified and N-acetylated derivatives of L-methionine and L-cysteine using a combination of 1H NMR and
Externí odkaz:
https://doaj.org/article/503308c8573a4ad7a13bf9d1b71a3363
Publikováno v:
Macromolecules. 55:2924-2939
Publikováno v:
Biomacromolecules. 22:5290-5306
This contribution describes the design and synthesis of multifunctional micelles based on amphiphilic brush block copolymers (BBCPs) for imaging and selective drug delivery of natural anticancer compounds. Well-defined BBCPs were synthesized via one-
Publikováno v:
Chemical Communications. 57:7398-7401
We present a straightforward “click chemistry” methodology for the functionalization of water-oxidation catalyst iridium oxide nanoparticles (IrOx-NPs) with a multi-functionalized porphyrin-based photosynthetic model as sensitizer for the prepara
Publikováno v:
ACS Applied Polymer Materials. 2:5790-5797
Chronic wounds associated with diabetes remain a worldwide clinical challenge. Substance P (SP), which is an 11-amino acid neuropeptide secreted in the skin mainly by sensory neurons, has been repo...
Autor:
Carolyne B. Braga, Valéria Helena Alves Cagnon, Larissa Akemi Kido, Celina de Almeida Lamas, Catia Ornelas, Ronaldo A. Pilli, Ellen Nogueira Lima
Publikováno v:
ACS Biomaterials Science & Engineering. 6:2929-2942
Goniothalamin (GTN), a natural compound isolated from Goniothalamus species, has previously demonstrated cytotoxic activity against several cancer cell lines. However, similarly to many natural and synthetic anticancer compounds, GTN presents toxicit
Autor:
Fabiano da Silveira Santos, Fabiano Severo Rodembusch, Vanessa Pereira de Souza, Catia Ornelas, Dennis Russowsky, Carolyne B. Braga, Ronaldo A. Pilli
Publikováno v:
New Journal of Chemistry. 44:12440-12451
A series of new hybrid fluorescent Biginelli compounds, including a Monastrol derivative, were designed and synthesized with good yields. The photophysical studies revealed dual fluorescence emission, attributed to excited enol forms (E*) and tautome
Publikováno v:
New Journal of Chemistry. 44:4694-4703
The quest for alternative therapeutic agents with safe and effective profiles is one of the biggest challenges in oncology. Folate-targeted therapy can deliver drugs selectively into malignant cells via the Frα receptor, whereas bioorganometallic ch