Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Carolyne, Smith"'
Autor:
Katarina Blagovic, Armon Sharei, Howard Bernstein, Scott Loughhead, Carolyne Smith, Lindsay Moore, Emrah Ilker Ozay
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/445a583719904b259c20cae5dc822b54
Autor:
Michael Maloney, Carolyne Smith, Anita Venkitaraman, Christian Yee, Miye Jacques, Kelan Hlavaty, Melissa Myint
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/432aba8003874e85af421073ff3a9dd4
Autor:
Matthew G. Booty, Kelan A. Hlavaty, Adam Stockmann, Emrah Ilker Ozay, Carolyne Smith, Lina Tian, Edylle How, Disha Subramanya, Anita Venkitaraman, Christian Yee, Olivia Pryor, Kelly Volk, Katarina Blagovic, Ildefonso Vicente-Suarez, Defne Yarar, Melissa Myint, Amy Merino, Jonathan Chow, Tarek Abdeljawad, Harry An, Sophia Liu, Shirley Mao, Megan Heimann, LeeAnn Talarico, Miye K. Jacques, Eritza Chong, Lucas Pomerance, John T. Gonzalez, Ulrich H. von Andrian, Klavs F. Jensen, Robert Langer, Hendrik Knoetgen, Christine Trumpfheller, Pablo Umaña, Howard Bernstein, Armon Sharei, Scott M. Loughhead
Publikováno v:
The Journal of Immunology. 208:929-940
CD8+ T cell responses are the foundation of the recent clinical success of immunotherapy in oncologic indications. Although checkpoint inhibitors have enhanced the activity of existing CD8+ T cell responses, therapeutic approaches to generate Ag-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::551c4a24375fe0d38f164f720ccd57bb
https://doi.org/10.4049/jimmunol.2100656
https://doi.org/10.4049/jimmunol.2100656
Autor:
Carolyne Smith, Lindsay J. Moore, Blagovic Katarina, Howard Bernstein, Emrah Ilker Ozay, Armon Sharei, Scott Loughhead
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundT cell responses are at the core of checkpoint inhibitor success in treating cancer; however, generating targeted antigen presentation to stimulate T cell responses remains challenging. Here, we take advantage of the natural process of eryp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb74960ffa663b05d354057bdf1ce91b
https://doaj.org/article/445a583719904b259c20cae5dc822b54
https://doaj.org/article/445a583719904b259c20cae5dc822b54
Autor:
Matthew G, Booty, Kelan A, Hlavaty, Adam, Stockmann, Emrah Ilker, Ozay, Carolyne, Smith, Lina, Tian, Edylle, How, Disha, Subramanya, Anita, Venkitaraman, Christian, Yee, Olivia, Pryor, Kelly, Volk, Katarina, Blagovic, Ildefonso, Vicente-Suarez, Defne, Yarar, Melissa, Myint, Amy, Merino, Jonathan, Chow, Tarek, Abdeljawad, Harry, An, Sophia, Liu, Shirley, Mao, Megan, Heimann, LeeAnn, Talarico, Miye K, Jacques, Eritza, Chong, Lucas, Pomerance, John T, Gonzalez, Ulrich H, von Andrian, Klavs F, Jensen, Robert, Langer, Hendrik, Knoetgen, Christine, Trumpfheller, Pablo, Umaña, Howard, Bernstein, Armon, Sharei, Scott M, Loughhead
Publikováno v:
J Immunol
CD8(+) T cell responses are the foundation of the recent clinical success of immunotherapy in oncologic indications. Although checkpoint inhibitors have enhanced the activity of existing CD8(+) T cell responses, therapeutic approaches to generate Ag-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::61c05f1e7053ee5957f5321dd8d2e325
https://pubmed.ncbi.nlm.nih.gov/35091434
https://pubmed.ncbi.nlm.nih.gov/35091434
Autor:
Michael F. Maloney, Emrah Ilker Ozay, Katarina Blagovic, Carolyne Smith, Andrea A. Silva, Amber Martin, Sanjana Manja, Madhav Upadhyay, Lindsay J. Moore, Ryan Stagg, Henry Mack, Christine Trumpfheller, Pablo Umana, Armon Sharei, Howard Bernstein, Scott M. Loughhead
Publikováno v:
Cancer Research. 82:2853-2853
Antigen-specific CD8+ T cells are critical for mounting an effective immune response against tumors. Generation of antigen-specific T cells require interactions with multiple signals produced by antigen presenting cells (APCs). These signals are comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a260e0910f2aaaaa24f0d717b8f4120e
https://doi.org/10.1158/1538-7445.am2022-2853
https://doi.org/10.1158/1538-7445.am2022-2853
Autor:
Miye Jacques, Katherine Seidl, Amritha Ramakrishnan, Christian Yee, Michael F. Maloney, Melissa Myint, Howard Bernstein, Carolyne Smith, Anita Venkitaraman, Scott Loughhead, Armon Sharei, Defne Yarar, Hlavaty Kelan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Antigen-specific CD8+ T cell activity is critical for mounting an effective immune response in a wide range of indications, including immune-oncology and infectious diseases. Methods To elicit antigen-specific CD8+ T cell activity, we used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73760f9047018fc74450a79319f23740
https://doi.org/10.1136/jitc-2020-sitc2020.0169
https://doi.org/10.1136/jitc-2020-sitc2020.0169
Autor:
Scott Loughhead, Armon Sharei, Defne Yarar, Amritha Ramakrishnan, Katherine Seidl, Carolyne Smith, Howard Bernstein
Publikováno v:
Cancer Research. 81:1524-1524
KRAS mutations are shared across multiple cancer types and are most commonly found in cancers of the lung, pancreas, and colon. While recently developed drugs blocking signaling driven by KRAS G12C mutations have shown promise in the clinic, there is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2377410066254d6f8df8e8ed71ae31c6
https://doi.org/10.1158/1538-7445.am2021-1524
https://doi.org/10.1158/1538-7445.am2021-1524
Autor:
Carolyne Smith, Michael F. Maloney, Paul R. Dunbar, Howard Bernstein, Emrah Ilker Ozay, Scott Loughhead, Christian Yee, Mubeen Mosaheb, Kelly Volk, Katherine Seidl, Amy Merino
Publikováno v:
Cancer Research. 81:1523-1523
Antigen-specific CD8+ T cell priming is critical for mounting an effective immune response against altered self or foreign antigens that are found in most tumors and virally infected cells. T cell priming events require antigen presenting cells (APCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95c681a543c50df317402e73aefd16ef
https://doi.org/10.1158/1538-7445.am2021-1523
https://doi.org/10.1158/1538-7445.am2021-1523
Autor:
Carolyne Smith, Anuradha Vivekanandan-Giri, Martin Playford, Celine Berthier, Matthias Kretzler, Nehal Mehta, Subramaniam Pennathur, Mariana Kaplan
Publikováno v:
The Journal of Immunology. 194:121.1-121.1
Lupus (SLE) patients are fifty times more likely to experience a cardiovascular event compared to age- and sex-matched controls. High levels of oxidized HDL (oxHDL) in SLE patients may contribute to this association. Under normal conditions, unoxidiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1a9bbab7c836b8e8393c80aec34ed52
https://doi.org/10.4049/jimmunol.194.supp.121.1
https://doi.org/10.4049/jimmunol.194.supp.121.1