Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Carolyn van Pelt"'
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11847 (2010)
Improved understanding of lung cancer development and progression, including insights from studies of animal models, are needed to combat this fatal disease. Previously, we found that mice with a knockout (KO) of G-protein coupled receptor 5A (Gprc5a
Externí odkaz:
https://doaj.org/article/8c1e3483bd894964b8102c68e09a74bf
Autor:
Yun, Zhang, Shunbin, Xiong, Qin, Li, Sophia, Hu, Mehrnoosh, Tashakori, Carolyn, Van Pelt, Mingjian James, You, Laura, Pageon, Guillermina, Lozano
Publikováno v:
The Journal of pathology. 233(4)
Mdm2, an E3 ubiquitin ligase, negatively regulates the tumour suppressor p53. In this study we utilized a conditional Mdm2 allele, Mdm2(FM) , and a CAG-CreER tamoxifen-inducible recombination system to examine the effects of global Mdm2 loss in adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a90c85558cb7d95d01030d2803d5af2d
https://pubmed.ncbi.nlm.nih.gov/24789767
https://pubmed.ncbi.nlm.nih.gov/24789767
Publikováno v:
Journal of Neuro-Oncology. 4:209-218
Mouse B16 melanoma sublines were selected sequentially for their abilities to colonize brain meninges and leptomeninges of C57BL/6 mice. After 14 selections subline B16-B14b was established that formed significantly more brain tumor colonies than the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50861338842828fbbe9297510b34e50
https://doi.org/10.1007/bf00150612
https://doi.org/10.1007/bf00150612