Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Carolyn V. Coulter"'
Autor:
Carolyn V. Coulter
Publikováno v:
International Journal of Clinical Pharmacy. 40:775-777
Renal patients have a high incidence of adverse drug reactions due to both pharmacokinetic and pharmacodynamic changes and detecting these adverse drug reactions relies heavily on having a high index of suspicion-which seems to be invoked through exp
Autor:
Stephen B. Duffull, Frederiek E. Vos, Patrick J. Manning, Robert J. Walker, John B. W. Schollum, Carolyn V. Coulter
Publikováno v:
Nephrology. 17:182-188
Aim: Due to altered red blood cell survival and erythropoietin therapy glycated haemoglobin (HbA1c) may not accurately reflect long-term glycaemic control in patients with diabetes and chronic kidney disease (CKD). Glycated albumin (GA) and fructosam
Autor:
Robert J. Walker, Carolyn V. Coulter, John B. W. Schollum, Terrence C.A. Doyle, Stephen B. Duffull, Frederiek E. Vos
Publikováno v:
American Journal of Kidney Diseases. 58:591-598
Background Shortening of red blood cell (RBC) survival contributes to the anemia of chronic kidney disease. The toxic uremic environment accounts for the decreased RBC life span. The contribution of mechanical damage caused by hemodialysis to the sho
Publikováno v:
Journal of Theoretical Biology. 268:39-49
A statistical model for the survival time of red blood cells (RBCs) with a continuous distribution of cell lifespans is presented. The underlying distribution of RBC lifespans is derived from a probability density function with a bathtub-shaped hazar
Publikováno v:
Clinical Pharmacology & Therapeutics. 90:243-245
Electrocardiograms (ECGs) from a case series of 86 amisulpride overdose events in 66 patients were reviewed for abnormal QT intervals and torsade de pointes (TdP). Eight patients exhibited TdP. In this investigative case series, the magnitude of prol
Publikováno v:
Fullerene Science and Technology. 9:339-350
A monofunctionalised fullerene triphenylphosphonium salt has been synthesised to investigate the potential for adaptation of fullerenes for biological application. The redox properties of fullerenes make them effective radical scavengers and conseque
Autor:
Carolyn M. Porteous, Michael P. Murphy, Carolyn V. Coulter, Robin A.J. Smith, William K. Porteous, Geoffrey F. Kelso, Gillian Hughes, Elizabeth C. Ledgerwood
Publikováno v:
Journal of Biological Chemistry. 276:4588-4596
With the recognition of the central role of mitochondria in apoptosis, there is a need to develop specific tools to manipulate mitochondrial function within cells. Here we report on the development of a novel antioxidant that selectively blocks mitoc
Publikováno v:
Free Radical Biology and Medicine. 28:1547-1554
Mitochondrial oxidative damage and dysfunction contributes to a number of cell pathologies. To investigate how this damage affects cell function we have developed mitochondrially targeted antioxidants and thiol reagents by covalently linking them to
Publikováno v:
Pesticide Science. 55:887-895
Dihydrodipicolinate synthase (DHDPS) (EC 4.2.1.52) and dihydrodipicolinate reductase (DHDPR) (EC 1.3.1.26) have attracted much recent attention as potential herbicide targets. DHDPS was feedback-inhibited by (S)-lysine; inhibition was reversible and
Autor:
Amy Jane Bodington, Rhiannon Braund, Anna-Marie Greig, Brooke Jane Marshall, Lauren Margaret Giles, Carolyn V. Coulter, Larissa Jane Heaslip
Publikováno v:
International journal of clinical pharmacy. 36(3)
Background There can be a lack of transfer of information between hospitals and community pharmacies following patient discharge, which puts patients at a high risk of suffering drug related problems (DRPs). Community pharmacy plays a vital role in i