Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Carolyn Shembrey"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
The protective role of Natural Killer (NK) cell tumour immunosurveillance has long been recognised in colorectal cancer (CRC). However, as most patients show limited intra-tumoral NK cell infiltration, improving our ability to identify those with hig
Externí odkaz:
https://doaj.org/article/dcbd1cafc74045d0a6e02eb99f80274f
Autor:
Emily J. Lelliott, Kelly M. Ramsbottom, Mark R. Dowling, Carolyn Shembrey, Tahereh Noori, Conor J. Kearney, Jessica Michie, Ian A. Parish, Margaret A. Jordan, Alan G. Baxter, Neil D. Young, Amelia J. Brennan, Jane Oliaro
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cytotoxic lymphocytes are essential for anti-tumor immunity, and for effective responses to cancer immunotherapy. Natural killer cell granule protein 7 (NKG7) is expressed at high levels in cytotoxic lymphocytes infiltrating tumors from patients trea
Externí odkaz:
https://doaj.org/article/c8e517cb608a45a58a1cfaec14b8b317
Autor:
Carolyn Shembrey, Jai Smith, Mélodie Grandin, Nathalia Williams, Hyun-Jung Cho, Christina Mølck, Corina Behrenbruch, Benjamin NJ. Thomson, Alexander G. Heriot, Delphine Merino, Frédéric Hollande
Publikováno v:
Cancers, Vol 14, Iss 3, p 581 (2022)
Geno- and phenotypic heterogeneity amongst cancer cell subpopulations are established drivers of treatment resistance and tumour recurrence. However, due to the technical difficulty associated with studying such intra-tumoural heterogeneity, this phe
Externí odkaz:
https://doaj.org/article/271ee8fcc235466b838aca3688212920
Publikováno v:
Cancers, Vol 11, Iss 9, p 1217 (2019)
Metastatic tumors are the primary cause of cancer-related mortality. In recent years, interest in the immunologic control of malignancy has helped establish escape from immunosurveillance as a critical requirement for incipient metastases. Our improv
Externí odkaz:
https://doaj.org/article/8f386218c21a467f84aba16264656ecd
Autor:
Frédéric Hollande, Erica K. Sloan, Andrew F. Hill, Julie Pannequin, Melissa J. Davis, Alain Puisieux, Alexander G. Heriot, Jean-Marc Pascussi, Antoni Castells, Jean-Francois Bourgaux, Michel Prudhomme, Fanny Grillet, Ramona Nasr, Sophie Guelfi, Meritxell Gironella, Marina Papin, Corina Behrenbruch, Christina Mølck, Carolyn Shembrey, Laura M. Beyit, Lesley Cheng, Shir Lin Koh, Sophie Paquet-Fifield
This table presents the Top 10 most enriched KEGG pathways identified from the panel of miRNAs regulated by claudin-2, along with their enrichment score and p-value.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad4e9faf0744eadb376f5cb1a9c1b83
https://doi.org/10.1158/0008-5472.22417740.v1
https://doi.org/10.1158/0008-5472.22417740.v1
Autor:
Frédéric Hollande, Erica K. Sloan, Andrew F. Hill, Julie Pannequin, Melissa J. Davis, Alain Puisieux, Alexander G. Heriot, Jean-Marc Pascussi, Antoni Castells, Jean-Francois Bourgaux, Michel Prudhomme, Fanny Grillet, Ramona Nasr, Sophie Guelfi, Meritxell Gironella, Marina Papin, Corina Behrenbruch, Christina Mølck, Carolyn Shembrey, Laura M. Beyit, Lesley Cheng, Shir Lin Koh, Sophie Paquet-Fifield
This file contains all supplemental Figures, as well as legends for both Supplemental Figures and Supplemental Tables, as well as Supplemental methods and associated references
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9627fd0182f64626430eef845db879
https://doi.org/10.1158/0008-5472.22417749.v1
https://doi.org/10.1158/0008-5472.22417749.v1
Autor:
Frédéric Hollande, Erica K. Sloan, Andrew F. Hill, Julie Pannequin, Melissa J. Davis, Alain Puisieux, Alexander G. Heriot, Jean-Marc Pascussi, Antoni Castells, Jean-Francois Bourgaux, Michel Prudhomme, Fanny Grillet, Ramona Nasr, Sophie Guelfi, Meritxell Gironella, Marina Papin, Corina Behrenbruch, Christina Mølck, Carolyn Shembrey, Laura M. Beyit, Lesley Cheng, Shir Lin Koh, Sophie Paquet-Fifield
Posttreatment recurrence of colorectal cancer, the third most lethal cancer worldwide, is often driven by a subpopulation of cancer stem cells (CSC). The tight junction (TJ) protein claudin-2 is overexpressed in human colorectal cancer, where it enha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f37cc05f22c32c9d261be35fed759d
https://doi.org/10.1158/0008-5472.c.6509922.v1
https://doi.org/10.1158/0008-5472.c.6509922.v1
Autor:
Carolyn Shembrey, Corina Behrenbruch, Benjamin PT Loveday, Alexander G Heriot, Momeneh Foroutan, Frédéric Hollande
The protective role of Natural Killer (NK) cell tumour immunosurveillance has long been recognised in colorectal cancer (CRC). However, as most patients show limited intra-tumoral NK cell infiltration, improving our ability to identify those with hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6881c86f60e3ad8cc19c04546d1681b6
https://doi.org/10.1101/2022.04.29.489868
https://doi.org/10.1101/2022.04.29.489868
Autor:
Carolyn Shembrey, Jai Smith, Mélodie Grandin, Nathalia Williams, Hyun-Jung Cho, Christina Mølck, Corina Behrenbruch, Benjamin NJ. Thomson, Alexander G. Heriot, Delphine Merino, Frédéric Hollande
Publikováno v:
Cancers; Volume 14; Issue 3; Pages: 581
Cancers, Vol 14, Iss 581, p 581 (2022)
Cancers, Vol 14, Iss 581, p 581 (2022)
Geno- and phenotypic heterogeneity amongst cancer cell subpopulations are established drivers of treatment resistance and tumour recurrence. However, due to the technical difficulty associated with studying such intra-tumoural heterogeneity, this phe
Autor:
Alexander G. Heriot, Laura M. Beyit, Sophie Paquet-Fifield, Benjamin N. J. Thomson, Corina Behrenbruch, Yuan Cao, Jai Smith, Frédéric Hollande, Yan Qin, Carolyn Shembrey
Publikováno v:
Cancer Letters. 476:161-169
Remodeling of basement membrane proteins contributes to tumor progression towards the metastatic stage. One of these proteins, laminin 521 (LN521), sustains embryonic and induced pluripotent stem cell self-renewal, but its putative role in cancer is