Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Carolyn S. Grove"'
Autor:
Julia Weber, Jorge de la Rosa, Carolyn S. Grove, Markus Schick, Lena Rad, Olga Baranov, Alexander Strong, Anja Pfaus, Mathias J. Friedrich, Thomas Engleitner, Robert Lersch, Rupert Öllinger, Michael Grau, Irene Gonzalez Menendez, Manuela Martella, Ursula Kohlhofer, Ruby Banerjee, Maria A. Turchaninova, Anna Scherger, Gary J. Hoffman, Julia Hess, Laura B. Kuhn, Tim Ammon, Johnny Kim, Günter Schneider, Kristian Unger, Ursula Zimber-Strobl, Mathias Heikenwälder, Marc Schmidt-Supprian, Fengtang Yang, Dieter Saur, Pentao Liu, Katja Steiger, Dmitriy M. Chudakov, Georg Lenz, Leticia Quintanilla-Martinez, Ulrich Keller, George S. Vassiliou, Juan Cadiñanos, Allan Bradley, Roland Rad
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Identification of cancer genes altered by non-genetic mechanisms in B-cell lymphoma is challenging. Here, the authors report the development of transposon tools to perform genome-wide recessive screens in vivo and validate identified putative tumor s
Externí odkaz:
https://doaj.org/article/3cd9593b5a3c449085e3011eabf08516
Autor:
Thomas McKerrell, Naomi Park, Thaidy Moreno, Carolyn S. Grove, Hannes Ponstingl, Jonathan Stephens, Charles Crawley, Jenny Craig, Mike A. Scott, Clare Hodkinson, Joanna Baxter, Roland Rad, Duncan R. Forsyth, Michael A. Quail, Eleftheria Zeggini, Willem Ouwehand, Ignacio Varela, George S. Vassiliou
Publikováno v:
Cell Reports, Vol 10, Iss 8, Pp 1239-1245 (2015)
Clonal hemopoiesis driven by leukemia-associated gene mutations can occur without evidence of a blood disorder. To investigate this phenomenon, we interrogated 15 mutation hot spots in blood DNA from 4,219 individuals using ultra-deep sequencing. Usi
Externí odkaz:
https://doaj.org/article/74b21d94768d40e29ed1acd2efaa5501
Autor:
Carolyn S. Grove, George S. Vassiliou
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 8, Pp 941-951 (2014)
Acute myeloid leukaemia (AML) is an uncontrolled clonal proliferation of abnormal myeloid progenitor cells in the bone marrow and blood. Advances in cancer genomics have revealed the spectrum of somatic mutations that give rise to human AML and drawn
Externí odkaz:
https://doaj.org/article/8845df1d32564e4699b5f15f097753fe
Autor:
Oliver M. Dovey, Bin Chen, Annalisa Mupo, Mathias Friedrich, Carolyn S. Grove, Jonathan L. Cooper, Benjamin Lee, Ignacio Varela, Yue Huang, George S. Vassiliou
Publikováno v:
Haematologica, Vol 101, Iss 8 (2016)
Externí odkaz:
https://doaj.org/article/fde6a4f321db4abd94e78e0d58637ce3
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 10, p 2038 (2017)
The application of molecular genomics and our understanding of its clinical implications in the diagnosis, prognostication and treatment of lymphoproliferative disorders has rapidly evolved over the past few years. Of particular importance are indole
Externí odkaz:
https://doaj.org/article/28457dbe19054584bd39a3d43fa1698a
Autor:
Saumya E. Samaraweera, Tatjana Geukens, Debora A. Casolari, Tran Nguyen, Caitlyn Sun, Sheree Bailey, Sarah Moore, Jinghua Feng, Andreas W. Schreiber, Wendy T. Parker, Anna L. Brown, Carolyn Butcher, Peter G. Bardy, Michael Osborn, Hamish S. Scott, Dipti Talaulikar, Carolyn S. Grove, Christopher N. Hahn, Richard J. D'Andrea, David M. Ross
Publikováno v:
Pathology. 55:77-85
Refereed/Peer-reviewed The identification of a somatic mutation associated with myeloid malignancy is of diagnostic importance in myeloproliferative neoplasms (MPNs). Individuals with no mutation detected in common screening tests for variants in JAK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179f391d9840838f51051dcf2a1689a7
https://doi.org/10.1016/j.pathol.2022.05.015
https://doi.org/10.1016/j.pathol.2022.05.015
Autor:
Stéphane de Botton, Pierre Fenaux, Karen W.L. Yee, Christian Récher, Andrew H Wei, Pau Montesinos, David C. Taussig, Arnaud Pigneux, Thorsten Braun, Antonio Curti, Carolyn S Grove, Brian A. Jonas, Asim Khwaja, Ollivier Legrand, Pierre Peterlin, Montserrat Arnan, William Blum, Daniela Cilloni, Devendra K. Hiwase, Joseph G. Jurcic, Jürgen Krauter, Xavier Thomas, Justin M Watts, Jay Yang, Olga Polyanskaya, Julie Brevard, Jennifer Sweeney, Emma Barrett, Jorge Cortes
Publikováno v:
Blood Advances.
Olutasidenib (FT-2102) is a potent, selective, oral, small-molecule inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1). Overall, 153 IDH-1 inhibitor naïve patients with mIDH1R132 relapsed/refractory (R/R) acute myeloid leukemia (AML) received ol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a944ce0c57a29ffc0e803a3e07d9ff8
https://doi.org/10.1182/bloodadvances.2022009411
https://doi.org/10.1182/bloodadvances.2022009411
Publikováno v:
Pathology. 52:379-382
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fb0f8c37017a98d32b90b5f4f1d6d93
https://doi.org/10.1016/j.pathol.2020.01.678
https://doi.org/10.1016/j.pathol.2020.01.678
Autor:
Claire Hemmaway, Andrew H. Wei, Chung H. Kok, Nicola E. Potter, Richard Dillon, Ashish Bajel, Nigel H. Russell, Amanda F. Gilkes, James Anton Kuzich, Devendra K Hiwase, Adam Ivey, Jake Shortt, Abin Thomas, Emad Uddin Abro, Nisha Thiagarajah, James P Rowland, Matthew L. Smith, Kirsty Sharplin, Aditya Tedjaseputra, Carolyn S. Grove, Ing Soo Tiong
Monitoring of NPM1 mutant (NPM1mut) measurable residual disease (MRD) in acute myeloid leukemia (AML) has an established role in patients who are treated with intensive chemotherapy. The European LeukemiaNet has defined molecular persistence at low c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286cfe6c9b290acbd9859864007fb26f
https://orca.cardiff.ac.uk/id/eprint/146658/1/advancesadv2021005455.pdf
https://orca.cardiff.ac.uk/id/eprint/146658/1/advancesadv2021005455.pdf
Publikováno v:
Leukemia research. 105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95b707f838b7c2434d830985163fe9f7
https://pubmed.ncbi.nlm.nih.gov/33706968
https://pubmed.ncbi.nlm.nih.gov/33706968