Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Carolyn Rainer"'
Autor:
Bettina Kuenz, Andreas Lutterotti, Rainer Ehling, Claudia Gneiss, Monika Haemmerle, Carolyn Rainer, Florian Deisenhammer, Michael Schocke, Thomas Berger, Markus Reindl
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2559 (2008)
BackgroundThere is accumulating evidence from immunological, pathological and therapeutic studies that B cells are key components in the pathophysiology of multiple sclerosis (MS).Methodology/principal findingsIn this prospective study we have for th
Externí odkaz:
https://doaj.org/article/23836522eaf54f5e82b612549a9e54a2
Autor:
Michael C. Schmid, Ainhoa Mielgo, David A. Tuveson, Daniel H. Palmer, Fiona Campbell, Trish Murray, Arthur Taylor, Dannielle D. Engle, Muhammad S. Ahmed, Meirion L. Raymant, Sebastian R. Nielsen, Carolyn Rainer, Valeria Quaranta
The ability of disseminated cancer cells to evade the immune response is a critical step for efficient metastatic progression. Protection against an immune attack is often provided by the tumor microenvironment that suppresses and excludes cytotoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c50fc90d028394b7e23b08fae8143f
https://doi.org/10.1158/0008-5472.c.6510191.v1
https://doi.org/10.1158/0008-5472.c.6510191.v1
Autor:
Ainhoa Mielgo, Michael C. Schmid, Fiona Campbell, David A. Tuveson, Thomas Bogenrieder, Azzam Taktak, Sarah E. Coupland, Pedro A. Perez-Mancera, Danielle D. Engle, Ulrike Weyer-Czernilofsky, Valeria Quaranta, Sebastian R. Nielsen, Carolyn Rainer, Muhammad S. Ahmed, Almudena Santos, Lucy Ireland
Fig. S1. Primary M2-like macrophages express IGF-1 and IGF-2. Fig. S2. In the absence of chemotherapy, addition of MCM, IGF blockade or recombinant IGF does not affect proliferation or survival of pancreatic cancer cells. Fig.S3. MCM enhances resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06902771ee91c13e027d15cd82063e3a
https://doi.org/10.1158/0008-5472.22412769.v1
https://doi.org/10.1158/0008-5472.22412769.v1
Autor:
Ainhoa Mielgo, Michael C. Schmid, Fiona Campbell, David A. Tuveson, Thomas Bogenrieder, Azzam Taktak, Sarah E. Coupland, Pedro A. Perez-Mancera, Danielle D. Engle, Ulrike Weyer-Czernilofsky, Valeria Quaranta, Sebastian R. Nielsen, Carolyn Rainer, Muhammad S. Ahmed, Almudena Santos, Lucy Ireland
Supplementary Figure legends. Table S1. Clinical information from 40 consented PDA patient samples. Table S2. Clinical information from 16 consented PDA patient samples. Supplementary Materials and Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05193f27a952663e6bd42aea594e452f
https://doi.org/10.1158/0008-5472.22412772.v1
https://doi.org/10.1158/0008-5472.22412772.v1
Autor:
Michael C. Schmid, Ainhoa Mielgo, David A. Tuveson, Daniel H. Palmer, Fiona Campbell, Trish Murray, Arthur Taylor, Dannielle D. Engle, Muhammad S. Ahmed, Meirion L. Raymant, Sebastian R. Nielsen, Carolyn Rainer, Valeria Quaranta
Files in this Data Supplement: - Supplementary Figures. Figure S1: Loss of CD8+ T cell numbers during metastatic progression in PDAC patients and genetically engineered mouse model of pancreatic cancer. Figure S2: Colony stimulating factor 1 (CSF-1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b4529d16f73d999f81abb92634ac227
https://doi.org/10.1158/0008-5472.22418660.v1
https://doi.org/10.1158/0008-5472.22418660.v1
Autor:
Ainhoa Mielgo, Michael C. Schmid, Fiona Campbell, David A. Tuveson, Thomas Bogenrieder, Azzam Taktak, Sarah E. Coupland, Pedro A. Perez-Mancera, Danielle D. Engle, Ulrike Weyer-Czernilofsky, Valeria Quaranta, Sebastian R. Nielsen, Carolyn Rainer, Muhammad S. Ahmed, Almudena Santos, Lucy Ireland
Tumor-associated macrophages (TAM) and myofibroblasts are key drivers in cancer that are associated with drug resistance in many cancers, including pancreatic ductal adenocarcinoma (PDAC). However, our understanding of the molecular mechanisms by whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::767b3c11e3a8231146a3b420547451b4
https://doi.org/10.1158/0008-5472.c.6508512.v1
https://doi.org/10.1158/0008-5472.c.6508512.v1
Autor:
Gaia Bellomo, Carolyn Rainer, Valeria Quaranta, Yuliana Astuti, Meirion Raymant, Elzbieta Boyd, Ruth Stafferton, Fiona Campbell, Paula Ghaneh, Christopher M Halloran, Dean E Hammond, Jennifer P Morton, Daniel Palmer, Dale Vimalachandran, Robert Jones, Ainhoa Mielgo, Michael C Schmid
Publikováno v:
Gut. 71(11)
ObjectivePancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease and cytotoxic chemotherapy is the standard of care treatment for patients with advanced disease. Here, we investigate how the microenvironment in PDAC liver metastases re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52029c456495c4ce79ab3c589af468e5
https://pubmed.ncbi.nlm.nih.gov/35022267
https://pubmed.ncbi.nlm.nih.gov/35022267
Autor:
Valeria Quaranta, Trish Murray, Carolyn Rainer, Muhammad S Ahmed, Fiona Campbell, Sebastian R. Nielsen, Dannielle D. Engle, Meirion Llŷr Raymant, Michael C. Schmid, David A. Tuveson, Arthur Taylor, Ainhoa Mielgo, Daniel H. Palmer
Publikováno v:
Cancer Research
The ability of disseminated cancer cells to evade the immune response is a critical step for efficient metastatic progression. Protection against an immune attack is often provided by the tumor microenvironment that suppresses and excludes cytotoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394326fd5ec544fef1ecc3dcce6b184e
Autor:
Peter Lackner, Wolfgang Löscher, Tobias De Zordo, Michael Schocke, Carolyn Rainer, Franziska Di Pauli, Rainer Ehling, Viktoria Kraus, Andreas Lutterotti, Susanne Glatzl, Bettina Kuenz, Harald Hegen, Thomas Berger, Markus Reindl, Florian Deisenhammer
Publikováno v:
Journal of neuroimmunology. 287
Data from in vitro and animal studies support a neuroprotective role of glatiramer acetate (GA) in multiple sclerosis (MS). We investigated prospectively whether treatment with GA leads to clinical and paraclinical changes associated with neuroprotec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d459f3b87f421187e816016d566b7e4b
https://pubmed.ncbi.nlm.nih.gov/26439969
https://pubmed.ncbi.nlm.nih.gov/26439969
Autor:
Yong Sam Kim, Almudena Santos, Andrea Linford, David A. Tuveson, Emilio Hirsch, Carolyn Rainer, Takao Sakai, Perpetua Emeagi, Ainhoa Mielgo, Michael C. Schmid, Keiko Sakai, Sebastian R. Nielsen, Valeria Quaranta, Jeong Heon Ko, Dannielle D. Engle, Fiona Campbell, Lucy Ireland, Daniel H. Palmer
Publikováno v:
Nature Cell Biology. 18:822-822
Corrigendum: Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a237e5ff91ca78d23e08d3ee442097f
https://doi.org/10.1038/ncb3377
https://doi.org/10.1038/ncb3377