Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Carolyn R Maskin"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract It is critical to understand the molecular mechanisms governing the regulation of MITF, a lineage specific transcription factor in melanocytes and an oncogene in melanoma. We identified PPP6C, a serine/threonine phosphatase, as a key regulat
Externí odkaz:
https://doaj.org/article/f405f18ed76a46aa8b199e5000b0ef44
Autor:
Courtney A Balgobin, Paul J. Wrighton, Darya Mailhiot, Sean C. McConnell, Sara E DiNapoli, Jill L. O. de Jong, Caitlin K Gribbin, Yariv Houvras, Eleanor D. Quenzer, Isabel Nelson, Abigail Leonard, Raul Martinez-McFaline, Carolyn R Maskin, Arkadi Shwartz, Clara Kao, Wolfram Goessling
Publikováno v:
Nucleic Acids Research
CRISPR/Cas9 has become a powerful tool for genome editing in zebrafish that permits the rapid generation of loss of function mutations and the knock-in of specific alleles using DNA templates and homology directed repair (HDR). We examined the effici