Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Carolyn O'Driscoll"'
Publikováno v:
Journal of Neurochemistry. 118:915-927
Retinal degenerations such as Retinitis Pigmentosa remain difficult to treat given the diverse array of genes responsible for their aetiology. Rather than concentrate on specific genes, our focus is on identifying therapeutic avenues for the treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97cf142b4dcc6465d5188d7c32fd638b
https://doi.org/10.1111/j.1471-4159.2011.07354.x
https://doi.org/10.1111/j.1471-4159.2011.07354.x
Publikováno v:
Experimental Eye Research. 93:65-74
The benzopyran BP (3,4-dihydro-6-hydroxy-7-methoxy-2,2-dimethyl-1(2H)-benzopyran) is a free radical scavenger that is structurally similar to alpha-tocopherol and has provided neuro-protection in a number of disease models where oxidative stress is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd98e2895754e18e3d0e61be0b5443d7
https://doi.org/10.1016/j.exer.2011.04.007
https://doi.org/10.1016/j.exer.2011.04.007
Publikováno v:
Journal of Neurochemistry. 109:631-643
Rosiglitazone is a member of the thiazolidinedione family of synthetic peroxisome proliferator-activated receptor (PPAR) agonists. It is a selective ligand of the PPARgamma subtype and functions by regulating the transcription of insulin-responsive g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3b8ebb4fbe3f029985b2b8e85a4a1f
https://doi.org/10.1111/j.1471-4159.2009.05995.x
https://doi.org/10.1111/j.1471-4159.2009.05995.x
Publikováno v:
Journal of Neurochemistry. 105:524-536
Basic fibroblast growth factor (bFGF) has proven neuroprotective efficacy in the rodent retina against a diverse array of injurious stimuli. However, there is no consensus to date as to the molecular mechanisms underlying this neuroprotection. The st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f350406f2826a029f4ddefb4f06a00
https://doi.org/10.1111/j.1471-4159.2007.05189.x
https://doi.org/10.1111/j.1471-4159.2007.05189.x
Publikováno v:
Journal of Neurochemistry. 103:860-870
Although there is substantial evidence supporting the neuroprotective efficacy of basic fibroblast growth factor (bFGF) in the rodent retina there is no consensus to date as to the protective mechanism involved. We hypothesise that bFGF can assert it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc3a7b4028eca73dd5dd1cb9b39a838
https://doi.org/10.1111/j.1471-4159.2007.04827.x
https://doi.org/10.1111/j.1471-4159.2007.04827.x
Publikováno v:
Experimental Eye Research. 83:1482-1492
Apoptosis, a cellular process critical to retinal neurogenesis, has been implicated in several neurodegenerative disorders. As the retina matures the suppression of apoptosis occurs and the emphasis shifts towards survival. To identify the cellular c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff734ac6abcf48c33df721f5c1243e8
https://doi.org/10.1016/j.exer.2006.08.007
https://doi.org/10.1016/j.exer.2006.08.007
Publikováno v:
Cell Death & Differentiation. 11:252-260
Recent work has highlighted the importance of protein post-translational modifications such as phosphorylation (enzymatic) and nitrosylation (nonenzymatic) in the early stages of apoptosis. In this study, we have investigated the levels of protein ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05cc62f0b49e356aff1bb65f025fb1e0
https://doi.org/10.1038/sj.cdd.4401338
https://doi.org/10.1038/sj.cdd.4401338
Publikováno v:
Journal of neurochemistry. 118(5)
Retinal degenerations such as Retinitis Pigmentosa remain difficult to treat given the diverse array of genes responsible for their aetiology. Rather than concentrate on specific genes, our focus is on identifying therapeutic avenues for the treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8cd5c8a3ce2332abc206b99114501ca0
https://pubmed.ncbi.nlm.nih.gov/21689103
https://pubmed.ncbi.nlm.nih.gov/21689103