Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Carolyn Nicolson"'
Autor:
Giada Mattiuzzo, James Ashall, Kathryn S Doris, Kirsty MacLellan-Gibson, Carolyn Nicolson, Dianna E Wilkinson, Ruth Harvey, Neil Almond, Robert Anderson, Stacey Efstathiou, Philip D Minor, Mark Page
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142751 (2015)
The 2013-present Ebola virus outbreak in Western Africa has prompted the production of many diagnostic assays, mostly based on nucleic acid amplification technologies (NAT). The calibration and performance assessment of established assays and those u
Externí odkaz:
https://doaj.org/article/efcff35a8d694740a5cd3c51e4f3d362
Autor:
Rachel E. Johnson, Michelle Hamill, Ruth Harvey, Carolyn Nicolson, James S. Robertson, Othmar G. Engelhardt
Publikováno v:
PLoS ONE, Vol 7, Iss 6 (2012)
Externí odkaz:
https://doaj.org/article/45b992c63357418cae4b49a960d2ef4a
Autor:
Rachel E Johnson, Michelle Hamill, Ruth Harvey, Carolyn Nicolson, James S Robertson, Othmar G Engelhardt
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36241 (2012)
The candidate H5N1 vaccine virus NIBRG-14 was created in response to a call from the World Health Organisation in 2004 to prepare candidate vaccine viruses (CVVs) to combat the threat of an H5N1 pandemic. NIBRG-14 was created by reverse genetics and
Externí odkaz:
https://doaj.org/article/638d86473ccf42148e6cfe9882f69a7d
Autor:
Jessica A. Belser, Kortney M. Gustin, Irina Isakova, Taronna R. Maines, Othmar G. Engelhardt, Barbara A. Pokorny, Jeanmarie Silverman, Olga Zoueva, Doris Bucher, Eduardo O’Neill, R.W. Newman, Erin E. Verity, Jianhua Le, Nancy J. Cox, Rachel E. Johnson, James S. Robertson, Sarah Roseby, Sarina Camuglia, Xing Li, Rebecca Collin, Zhengshi Lin, Zhiping Ye, Terrence M. Tumpey, Ruben O. Donis, Chantal Wallis, Kate Guilfoyle, Catherine Agius, Xiyan Xu, Charles T. Davis, Carolyn Nicolson, Anne Curtis, Ramanunninair Manojkumar, Chi Ong, John Wood, Jacqueline M. Katz, Hang Xie, Diane Major, Amanda Balish, Steven Rockman, Ruth Harvey, Peter Schoofs, Rene Devis, Alexander Klimov, Pierre Rivailler, Zhu Guo, Aleksandr S. Lipatov, Li-Mei Chen
Publikováno v:
Vaccine. 29:1836-1843
Wild type human influenza viruses do not usually grow well in embryonated hens' eggs, the substrate of choice for the production of inactivated influenza vaccine, and vaccine viruses need to be developed specifically for this purpose. In the event of
Autor:
Carolyn Nicolson, Ruth J. Manvell, Katja Hoschler, Vo Minh Hien, Yasuhiro Takeuchi, Robin A. Weiss, Diane Major, Nigel J. Temperton, Menno De Jong, Maria Zambon, Do Quang Ha
Publikováno v:
Influenza and other respiratory viruses, 1(3), 105-112. Wiley-Blackwell
Influenza and Other Respiratory Viruses
Influenza and Other Respiratory Viruses
Background The World Health Organisation (WHO) recommended the development of simple, safe, sensitive and specific neutralization assays for avian influenza antibodies. We have used retroviral pseudotypes bearing influenza H5 hemagglutinin (HA) as sa
Publikováno v:
Vaccine. 23:2943-2952
Human influenza vaccine reference strains are prepared as required when an antigenically new strain is recommended by WHO for inclusion in the vaccine. Currently, for influenza A, these strains are produced by a double infection of embryonated hens'
Autor:
Margaret A. Conway, Patricia A. Johnson, Kingston H. G. Mills, James S. Robertson, Carolyn Nicolson, Janet M. Daly
Publikováno v:
International Congress Series. 1219:911-915
The relative ability of influenza HA DNA vaccines to induce cellular and humoral immunity after one or more doses and the persistence of this response have not been fully elucidated. HA DNA induces a potent Th1 response. Although this response wanes
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 11, p e0166761 (2016)
PLoS ONE, Vol 11, Iss 11, p e0166761 (2016)
Previous studies on influenza A(H1N1)pdm09 candidate vaccine viruses (CVVs) that had adapted to growth in embryonated chicken eggs by the acquisition of amino acid substitutions at HA positions 222 or 223 showed that improved protein yield could be c
Autor:
Regina Garcia-Beato, Geraldine Taylor, Nuria Rodriguez, José A. Melero, G.P. Bembridge, Carolyn Nicolson
Publikováno v:
Journal of General Virology. 81:2519-2523
Significant protection against respiratory syncytial virus (RSV) infection was induced in mice vaccinated intramuscularly (i.m.) with DNA encoding the F or G protein of RSV. The amounts of IgG1 of IgG2a antibodies in mice immunized with DNA-G alone w
Autor:
Philip D. Minor, Ann-Marie Riley, James S. Robertson, M. L. Bentley, Carolyn Nicolson, T. Corcoran, Glynis Dunn, Geoffrey C. Schild
Publikováno v:
Biologicals. 25:403-414
A recent publication reported the detection of low levels of the enzyme reverse transcriptase (RTase) in live viral vaccines prepared in chick embryo cells. The enzyme was detected using an assay with greatly increased sensitivity compared to more co