Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Carolyn Marquis"'
Autor:
Carolyn Marquis, Cindy L. Fonseca, Katelyn A. Queen, Lisa Wood, Sarah E. Vandal, Heidi L. H. Malaby, Joseph E. Clayton, Jason Stumpff
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Kinesin motor proteins are critical for maintaining mitotic spindle integrity, which is important for chromosome stability. Here, the authors show that the kinesin motor protein, KIF18A, permits the proliferation of chromosomally unstable cells and k
Externí odkaz:
https://doaj.org/article/155fe186fe17428f9306cda918e23864
Autor:
Zuzana Storchova, Lisa-Marie Stautmeister, Kathrin Laue, Nicholas J. Lyons, Mariya Kazachkova, Todd R. Golub, Andrew Jones, Stefano Santaguida, Sara Vanessa Bernhard, Jason Stumpff, Helen Tang, Marica Rosaria Ippolito, James M. McFarland, Adam J. Bass, Rameen Beroukhim, Uri Ben-David, Yael Cohen-Sharir, Irena Bockaj, Ankur K. Nagaraja, Carolyn Marquis, Diana C.J. Spierings, Mai Abdusamad, Floris Foijer, Heidi L.H. Malaby, Johanna Zerbib, René Wardenaar
Publikováno v:
Nature, 590(7846). Nature Publishing Group
Nature
Nature
Selective targeting of aneuploid cells is an attractive strategy for cancer treatment(1). However, it is unclear whether aneuploidy generates any clinically relevant vulnerabilities in cancer cells. Here we mapped the aneuploidy landscapes of about 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632fb9544da6ff2088c466a916cf5a86
https://research.rug.nl/en/publications/6435240d-9c09-4249-b11f-a46eeb586ffb
https://research.rug.nl/en/publications/6435240d-9c09-4249-b11f-a46eeb586ffb
Autor:
Joseph E. Clayton, Lisa Wood, Carolyn Marquis, Heidi L.H. Malaby, Katelyn A. Queen, Sarah E. Vandal, Cindy L. Fonseca, Jason Stumpff
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Chromosomal instability (CIN) is a hallmark of tumor cells caused by changes in the dynamics and control of microtubules that compromise the mitotic spindle. Thus, CIN cells may respond differently than diploid cells to treatments that target mitotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aca43cc7a45dfc0f482c244f8260a6a
https://pubmed.ncbi.nlm.nih.gov/33619254
https://pubmed.ncbi.nlm.nih.gov/33619254
Autor:
Mai Abdusamad, Sara Vanessa Bernhard, Jason Stumpff, James M. McFarland, Nicholas J. Lyons, Yael Cohen-Sharir, Stefano Santaguida, Zuzana Storchova, Helen Tang, Heidi L.H. Malaby, Kathrin Laue, Ankur K. Nagaraja, Marica Rosaria Ippolito, Todd R. Golub, Rameen Beroukhim, Mariya Kazachkova, Andrew Jones, Adam J. Bass, Carolyn Marquis, Uri Ben-David
Selective targeting of aneuploid cells is an attractive strategy for cancer treatment. Here, we mapped the aneuploidy landscapes of ~1,000 human cancer cell lines and classified them by their degree of aneuploidy. Next, we performed a comprehensive a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38d34b629aeb93a0c3070a3b9936b9f8
https://doi.org/10.1101/2020.06.18.159038
https://doi.org/10.1101/2020.06.18.159038