Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Carolyn M. Madden"'
Autor:
Colleen S. McCoy, Anthony J. Mannion, Yan Feng, Carolyn M. Madden, Stephen C. Artim, Gina G. Au, Mikayla Dolan, Jennifer L. Haupt, Monika A. Burns, Alexander Sheh, James G. Fox
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Cyclomodulins are virulence factors that modulate cellular differentiation, apoptosis, and proliferation. These include colibactin (pks), cytotoxic necrotizing factor (cnf), and cytolethal distending toxin (cdt). Pathogenic pks+, cnf+, and c
Externí odkaz:
https://doaj.org/article/bb38a18277ca4514935adb7729f9f87d
Autor:
Yan Feng, Anthony Mannion, Carolyn M. Madden, Alton G. Swennes, Catherine Townes, Charles Byrd, Robert P. Marini, James G. Fox
Publikováno v:
Gut Pathogens, Vol 9, Iss 1, Pp 1-15 (2017)
Abstract Background Many Escherichia coli strains are considered to be a component of the normal flora found in the human and animal intestinal tracts. While most E. coli strains are commensal, some strains encode virulence factors that enable the ba
Externí odkaz:
https://doaj.org/article/ab934e2349334fffabc429f09595afb4
Autor:
Anthony Mannion, Stephen C. Artim, Yan Feng, Jennifer L Haupt, Alexander Sheh, Colleen S. McCoy, James G. Fox, Carolyn M. Madden, Monika Burns, Gina G. Au, Mikayla Dolan
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Cyclomodulins are virulence factors that modulate cellular differentiation, apoptosis, and proliferation. These include colibactin (pks), cytotoxic necrotizing factor (cnf), and cytolethal distending toxin (cdt). Pathogenic pks+, cnf+, and cdt+ E. co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a1267db09d2db06992015644cb820e
https://pubmed.ncbi.nlm.nih.gov/33504843
https://pubmed.ncbi.nlm.nih.gov/33504843
Autor:
James G. Fox, Paul Chamberlain, Susanna Kurnick, Yan Feng, Anthony Mannion, Carolyn M. Madden
Publikováno v:
Prof. Fox vua Howard Silver
Although many Escherichia coli strains are considered commensals in mammals, strains encoding the cyclomodulin genotoxins are associated with clinical and subclinical disease in the urogenital and gastrointestinal tracts, meningitis, and inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b821aea625cc2d94667017e72f788a1
https://europepmc.org/articles/PMC6464076/
https://europepmc.org/articles/PMC6464076/
Publikováno v:
Vet Microbiol
PMC
PMC
© 2019 Elsevier B.V. Escherichia coli encoding colibactin (clb), cytolethal distending toxin (cdt), and hemolysin-associated cytotoxic necrotizing factor (cnf) are associated with various intestinal and extra-intestinal diseases in humans and animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3545287713473fae0154cba08ab4cade
https://pubmed.ncbi.nlm.nih.gov/31902483
https://pubmed.ncbi.nlm.nih.gov/31902483
Autor:
Rudolf Jaenisch, Zhongming Ge, Carolyn M. Madden, Kathleen E Scott, Johanne T. Jacobsen, Tyler J. Caron, Gabriel D. Victora, Vasudevan Bakthavatchalu, Katherine J. Wert, Anthony Mannion, Yan Feng, Alexis García, James G. Fox
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0194443 (2018)
PLoS ONE, Vol 13, Iss 3, p e0194443 (2018)
Immune-compromised mouse models allow for testing the preclinical efficacy of human cell transplantations and gene therapy strategies before moving forward to clinical trials. However, CRISPR/Cas9 gene editing of the Wsh/Wsh mouse strain to create an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8213d221682af4164fa70a8430fd594f
http://europepmc.org/articles/PMC5858775
http://europepmc.org/articles/PMC5858775
Autor:
Yan, Feng, Anthony, Mannion, Carolyn M, Madden, Alton G, Swennes, Catherine, Townes, Charles, Byrd, Robert P, Marini, James G, Fox
Publikováno v:
Gut Pathogens
Background Many Escherichia coli strains are considered to be a component of the normal flora found in the human and animal intestinal tracts. While most E. coli strains are commensal, some strains encode virulence factors that enable the bacteria to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::228aacdfd15ad749f12a2033c4514d7b
https://pubmed.ncbi.nlm.nih.gov/29225701
https://pubmed.ncbi.nlm.nih.gov/29225701
Autor:
Robert P. Marini, Charles P. Byrd, Anthony Mannion, Alton G. Swennes, Catherine Townes, Carolyn M. Madden, James G. Fox, Yan Feng
Publikováno v:
BioMed Central
Gut Pathogens, Vol 9, Iss 1, Pp 1-15 (2017)
Gut Pathogens, Vol 9, Iss 1, Pp 1-15 (2017)
Background Many Escherichia coli strains are considered to be a component of the normal flora found in the human and animal intestinal tracts. While most E. coli strains are commensal, some strains encode virulence factors that enable the bacteria to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d90a9a80c4d6371854d081033d723a7
http://hdl.handle.net/1721.1/113343
http://hdl.handle.net/1721.1/113343
Autor:
Alton G. Swennes, Charles P. Byrd, Ellen M. Buckley, Carolyn M. Madden, Nicola Parry, Rachel S. Donocoff, James G. Fox, Loretta Rodriguez
Publikováno v:
PMC
Rabbit-origin enteropathogenic Escherichia coli (EPEC) causes substantial diarrhea-associated morbidity and has zoonotic potential. A culture-based survey was undertaken to ascertain its prevalence. EPEC was isolated from 6/141 (4.3%) commercially-ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e985b92066406a292e8d67f7a5510f1
https://doi.org/10.1016/j.vetmic.2013.01.006
https://doi.org/10.1016/j.vetmic.2013.01.006
Autor:
Alexis García, James G. Fox, Zeli Shen, Yan Feng, Zhongming Ge, Carolyn M. Madden, Vasudevan Bakthavatchalu, Anthony Mannion
Publikováno v:
PMC
Escherichia coli strains have not been fully characterized in laboratory mice and are not currently excluded from mouse colonies. Colibactin (Clb), a cytotoxin, has been associated with inflammation and cancer in humans and animals. We performed bact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309a890201f15121b996c87e1559a781
https://orcid.org/0000-0001-9307-6116
https://orcid.org/0000-0001-9307-6116