Influence of aldosterone vs. endothelin receptor antagonism on renovascular function in liquorice-induced hypertension

Autor: Frank Ruschitzka, Carolyn M. B. Lunt, Martin Wehling, Bernhard Niggli, Sidney Shaw, Thomas F. Lüscher, Thomas Quaschning, Michael Christ

Publikováno v: Quaschning, Thomas; Ruschitzka, Frank; Niggli, Bernhard; Lunt, Carolyn M. B.; Shaw, Sidney; Christ, Michael; Wehling, Martin; Lüscher, Thomas F. (2001). Influence of aldosterone vs endothelin receptor antagonism on renovascular function in liquorice-induced hypertension. Nephrology, dialysis, transplantation, 16(11), pp. 2146-2151. Oxford University Press 10.1093/ndt/16.11.2146

BACKGROUND The enzyme 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2) provides mineralocorticoid receptor specificity for aldosterone by metabolizing glucocorticoids to their receptor inactive 11-dehydro derivatives. Inhibition of 11beta-HSD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79975e5e3ab7ca61ceea77b57c2a2f51
https://pubmed.ncbi.nlm.nih.gov/11682659