Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Carolyn Loveridge"'
Autor:
Carolyn Loveridge, Frances Docherty, Sarah Honeychurch, Nathalie Tasler, Linnea Soler, Lindsey Pope, Victoria Price, Beth Dickson
Publikováno v:
International Journal for the Scholarship of Teaching and Learning, Vol 18, Iss 1 (2024)
We are a group of teaching-focused academics who share a passion for learning, teaching and the Scholarship of Teaching and Learning (SoTL) in Higher Education (HE). In order to understand how practitioners from a diversity of backgrounds and discipl
Externí odkaz:
https://doaj.org/article/77929c6aa52d42198a6bcd09856d1bad
Autor:
Rachana Patel, Janis Fleming, Ernest Mui, Carolyn Loveridge, Peter Repiscak, Arnaud Blomme, Victoria Harle, Mark Salji, Imran Ahmad, Katy Teo, Freddie C Hamdy, Ann Hedley, Niels van den Broek, Gillian Mackay, Joanne Edwards, Owen J Sansom, Hing Y Leung
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 4, Pp n/a-n/a (2018)
Abstract Metastatic castration‐resistant prostate cancer (mCRPC) is a lethal form of treatment‐resistant prostate cancer and poses significant therapeutic challenges. Deregulated receptor tyrosine kinase (RTK) signalling mediated by loss of tumou
Externí odkaz:
https://doaj.org/article/f68a51d6e42349948384f58cf1f57479
Autor:
Linda K. Rushworth, Carolyn Loveridge, Mark Salji, Martin MacLeod, Ernest Mui, David Sumpton, Matthew Neilson, Ann Hedley, Laura Alexander, Elaine McCartney, Rachana Patel, Jan Wallace, Christian Delles, Rob Jones, Hing Y. Leung
Publikováno v:
BJU International. 131:236-243
To test for evidence of statin-mediated effects in patients with castration-resistant prostate cancer (CRPC) as post-diagnosis use of statins in patients with prostate cancer is associated with favourable survival outcome.The SPECTRE trial was a 6-we
Publikováno v:
Molecular Diagnosis & Therapy
Objective To evaluate the application of RNAscope in the clinical diagnostic field compared to the current ‘gold standard’ methods employed for testing gene expression levels, including immunohistochemistry (IHC), quantitative real time PCR (qPCR
Autor:
Stuart M. Pitson, Jaclyn S. Long, Francesca Tonelli, Evgeny V. Berdyshev, Keng Gat Lim, Tamara M. Leclercq, Carolyn Loveridge, Rothwelle J. Tate, Viswanathan Natarajan, Susan Pyne, Nigel J. Pyne
Publikováno v:
Journal of Biological Chemistry. 285:38841-38852
Sphingosine kinase 1 (SK1) is an enzyme that catalyzes the phosphorylation of sphingosine to produce the bioactive lipid sphingosine 1-phosphate (S1P). We demonstrate here that the SK1 inhibitor, SKi (2-(p-hydroxyanilino)-4-(p-chlorophenyl)thiazole)
Publikováno v:
Advances in Enzyme Regulation. 49:214-221
Sphingosine 1-phosphate (S1P) is a bioactive lipid that is formed by the phosphorylation of sphingosine by the enzyme, sphingosine kinase. S1P regulates cell function via a family of five closely related G-protein-coupled receptors (GPCR) termed S1P1
Autor:
Jaclyn S. Long, Keng Gat Lim, Gabor Tigyi, Nigel J. Pyne, Susan Pyne, Robert Bittman, Carolyn Loveridge, Francesca Tonelli, Stuart M. Pitson
Publikováno v:
Cellular Signalling
Sphingosine kinase 1 (SK1) is an enzyme that catalyses the phosphorylation of sphingosine to produce the bioactive lipid sphingosine 1-phosphate (S1P). We demonstrate here that FTY720 (Fingolimod™) and (S)- FTY720 vinylphosphonate are novel inhibit